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(1)
By Target- Apoptosis
- Microtubule Associated(1)
- PROTACs(1)
- Others(2)
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Results for "
fc-11
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products1
- Recombinant Protein2
FC 11
T411642271035-37-9In house
FC 11 is a highly potent focal adhesion Ki nase (FAK) PROTAC®Degrader (DC50 values are 40 to 370 pM depending on cell line), which is composed of the FAK inhibitor PF 562217 joined by a linker to the cereblon-binding ligand Pomalidomide. The effects of FC 11 are reversible upon compound wash out. FC 11 also degrades autophosphorylated FAK (pFAKtyr397), displaying near complete degradation after 3 hours at 100 nM in TM3 cells.
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