fbpase

FBPase-IN-3 (compound 45) is an inhibitor of FBPase (fructose-1,6-bisphosphatase), exhibiting a potent inhibitory activity with an IC50 of 2.08 μM. This compound demonstrates strong antihyperglycemic activity by inhibiting gluconeogenesis.

FBPase-IN-4 (Compound 11 n) is an effective inhibitor of FBPase (Fructose-1,6-bisphosphatase), with a Ki value of 1.78 μM. This compound is utilized in research related to type 2 diabetes.

FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) is a fructose 1,6-bisphosphatase-1 inhibitor.

FBPase-IN-2 (HS36), a potent covalent inhibitor of Fructose-1,6-bisphosphatase (FBPase), exhibits an IC50 of 0.15 μM and effectively reduces glucose production in hepatocytes, making it relevant for type 2 diabetes mellitus research [1].

FBPase-IN-1 is an FBPase inhibitor and a herbicide that lowers blood glucose levels. It is used in studies of type 2 diabetes.

MB-07729 is a potent non-competitive inhibitor of fructose-1,6-bisphosphate with IC50 values of 189, 121 and 31 nM in rat, monkey and human, respectively, for the study of diabetes.

Managlinat dialanetil (MB06322) is an orally available and potent fructose 1,6-bisphosphatase (FBPase) inhibitor with hypoglycaemic activity for the study of type 2 diabetes.

MB07803 is an orally available prodrug of an effective, noncompetitive inhibitor of fructose 1,6-bisphosphatase (FBPase) (EC50: 140 nM and t1/2 of 7.6±2.9 h).This compound is unstable in powder form and other related salt forms are recommended.

(Rac)-Managlinat dialanetil ((Rac)-MB06322) is the racemate of Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.

MB05032 is a potent fructose-,-bisphosphatase inhibitor that inhibits gluconeogenesis and reduces d-lactate-triggered ETosis.

D-Fructose 6-phosphate dipotassium is an endogenous metabolite found in saliva that influences cell growth and autophagy. It is produced by the hydrolysis of Fructose-1,6-bisphosphatase (FBPase). Under the action of phosphoglucose isomerase, D-Fructose 6-phosphate dipotassium can be converted into D-glucose 6-phosphate (HY-112537). This compound acts as a sugar intermediate in both the glycolysis and pentose phosphate pathways. D-Fructose 6-phosphate dipotassium is used in research related to Lewy body dementia.