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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11234 | ESI-08 | cAMP | |
ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation. | |||
T15247 | ESI-05 | NSC 116966 | cAMP |
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation. | |||
T6666 | Sevelamer Carbonate | Others | |
Sevelamer carbonate is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. | |||
T39195 | YM-244769 dihydrochloride | Calcium Channel | |
YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 dihydrochloride has efficient protective effects on neurons and kidneys. | |||
T9888 | YM-244769 | 3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]- | Calcium Channel |
YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 has efficient protective effec... | |||
T9198 | SCH54292 | Ras | |
SCH-54292 is a GDP exchange inhibitor. | |||
T2089 | Eniporide | ATPase | |
Eniporide is a Na(+)/H(+) exchange inhibitor. | |||
T5319 | Rimeporide | EMD-87580 | Sodium Channel |
Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor. | |||
T5333 | Rimeporide hydrochloride | EMD-87580 hydrochloride | Sodium Channel |
Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor. | |||
T23969 | DCAI | Others | |
DCAI is an inhibitor of nucleotide exchange and nucleotide release acting by binding to the pocket adjacent to the Ras-SOS interface. | |||
T16897 | SM-6586 | Na+/Ca2+ Exchanger , Sodium Channel | |
SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular disease and hypertension, among other diseases. | |||
TP2131L | Rac1 Inhibitor W56 acetate(1095179-01-3 free base) | Rho | |
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1. | |||
T67766 | HHS-0701 | Others | |
HHS-0701 is a sulfur-triazole exchange (SuTEx) ligand. HHS-0701 is a potent inhibitor of tyrosine-reactive prostaglandin reductase 2 (PTGR2). HHS-0701 can block PTGR2 metabolism of the lipid substrate 15-Keto-PGE2. | |||
T13591 | Calcium polystyrene sulfonate | Poly(styrenesulfonic acid) calcium salt | Others |
Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) is an ion-exchange resin. Calcium polystyrene sulfonate reduces blood levels of potassium and can be used for research on the treatment of hyperkale... | |||
T24154 | I942 | I 942,I-942 | cAMP |
I942 is a novel, selective ACyclic nucleotide (NCN) EPAC1 agonist that activates exchange proteins to regulate inflammatory gene expression in human umbilical blood tubes and inhibit pro-inflammatory cytokine signaling a... | |||
T20110 | Ethylene thiourea | ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372 | Others |
Ethylene thiourea (NCIC03372) is a pesticide used in fruit and vegetable production. Ethylene thiourea is also used as a novel contrast agent for MRI studies based on proton chemical exchange-dependent saturation transfe... | |||
T12616L | CE3F4 | cAMP | |
CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1; IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively). | |||
T5391 | Bepridil hydrochloride | CERM 1978 | Calcium Channel |
Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels. | |||
T78823 | Quorum Sensing-IN-3 | QS-IN-1 | Antibacterial |
Quorum Sensing-IN-3 (QS-IN-1) is a compound with inhibitory effects on bacterial community sensing, which inhibits the exchange of information between bacteria and inhibits biofilm formation. | |||
T16564 | PPADS tetrasodium | P2X Receptor , Na+/Ca2+ Exchanger | |
PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na/Ca²⁺ exchange in guinea pig airway smooth muscle and is neuroprotective against glutamate/NMDA toxicity.PPADS tetrasodiuma in... |