enveloped

Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host cell membrane.

Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against enveloped and non-enveloped viruses, suppressing virus propagation and modulating the expression of inflammatory cytokines for use as an anti-influenza virus agent [3]. It effectively inhibits the fusion of the virus with host cells [1] [2] and is an efficient inhibitor of SARS-CoV-2 in vitro [2].

IHVR-11029 is a potent inhibitor of ER α-glucosidase. IHVR-11029 is active against multiple hemorrhagic fever viruses and efficiently disrupts the morphogenesis of a broad spectrum of enveloped viruses.

LJ-001 shows broad-spectrum activity against virtually all enveloped RNA and DNA viruses. LJ001 inhibits the infection of transmissible gastroenteritis virus (TGEV) and porcine delta coronavirus (PDCoV).

F8-S43-S3 is a highly effective entry inhibitor targeting enveloped viruses. It exhibits significant in vitro neutralizing activity against various influenza strains by binding to specific viral surface glycoproteins and interfering with the membrane fusion process.

Pradimicin A (PRM-A) is a compound with potent antifungal capabilities, demonstrating a minimum inhibitory concentration (MIC) of 4 μg/mL against Candida rugosa. It also exhibits antiviral activity against viruses such as CoV, HIV, and other enveloped viruses. Additionally, Pradimicin A possesses the ability to aggregate and specifically recognize d-Man in the presence of Ca2+ ions [1] [2].

SARS-CoV-2-IN-25 (Compound CP026) is a potent inhibitor of SARS-CoV-2 spike pseudoparticle transduction, with an inhibitory concentration (IC50) of 1.6 μM. It effectively inhibits both enveloped viruses and liposomes [1].

SARS-CoV-2-IN-25 (Compound CP026) disodium, a potent inhibitor of SARS-CoV-2 spike pseudoparticle transduction, demonstrates significant efficacy with an IC50 value of 1.6 μM. It also effectively inhibits enveloped viruses and liposomes, highlighting its broad-spectrum antiviral potential.

Human α-defensin 5 is an antiviral peptide that inhibits the infection of non-enveloped viruses such as AdV, HPV, and polyomaviruses, with an IC50 range of 0.6-1.25 μM specifically for HPV16. It functions by binding to the viral capsid and preventing viral escape from the endosome. Additionally, Human α-defensin 5 enhances HIV attachment to the cell surface and exhibits parasiticidal activity [1].

Antiviralagent 58 (Compound J1) is an orally active antiviral agent that exhibits broad-spectrum activity against enveloped viruses. It effectively targets various pathogens, including Influenza A virus (IAV), Respiratory Syncytial Virus (RSV), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Human Coronavirus OC43 (HCoV-OC43), and Herpes Simplex Virus types 1 and 2 (HSV-1 and HSV-2).

Monocaprin is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans.

Arbidol-d6 Hydrochloride is a deuterated compound of Arbidol Hydrochloride. Arbidol Hydrochloride has a CAS number of 131707-23-8. Arbidol (Umifenovir) hydrochloride, an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host cell membrane.