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Search Results for " congestive "

Targets

45

Compounds

5

Natural Products

Cat No. Product Name Synonyms Targets
T5329 Trandolapril Angiotensin-converting Enzyme (ACE)
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
T1462 Captopril SQ 14225,SQ-14534,SA333 RAAS
Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure.
T0342 Carvedilol phosphate hemihydrate Carvedilol phosphate,BM 14190 (phosphate hemihydrate) VEGFR , Others , Potassium Channel , LDL , Integrin , Gap Junction Protein , NADPH , Adrenergic Receptor , Autophagy
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom...
T0154 Nebivolol hydrochloride R 065824 hydrochloride,Nebivolol HCl,R-65824 Apoptosis , Adrenergic Receptor
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us...
T27596 Imazodan hydrochloride Imazodan HCl,CI 914,CI-914,CI914
Imazodan hydrochloride, a potent and selective type III phosphodiesterase inhibitor, is used for the treatment of chronic congestive heart failure.
T71744 Imazodan
Imazodan is a type III phosphodiesterase inhibitor that may be useful in the treatment of congestive heart failure.
T33600L (Rac)-Naxifylline (Rac)-Naxifylline((Rac)-166374-49-8) Others
(Rac)-Naxifylline may be used to study congestive heart failure.
T6595 Moexipril hydrochloride Moexipril HCl,RS-10085,SPM 925,CI-925 Apoptosis , RAAS
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.
T1182 Levocarnitine propionate hydrochloride Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,ST-261 Histamine Receptor
Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases.
T0805 Quinapril hydrochloride CI-906,PD-109452-2,Quinapril HCl RAAS
Quinapril hydrochloride (PD-109452-2) is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril hydrochloride is associated with a low rate of transie...
T8462 Enoximone PDE
Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.
T27119L (Rac)-Daglutril SLV 306 acetic acid,2-((3S)-3-(1-(2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentane-1-carboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid Others
(Rac)-Daglutril (SLV 306 acetic acid) is the racemate form of Daglutril. Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential ...
T2530 Levosimendan OR1259,OR1855 Potassium Channel , PDE , Carbonic Anhydrase , Autophagy
Levosimendan (OR1259) is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It increases the sensitivity of the heart to calcium, thus increasing cardiac contractility without ...
T16444 PD-118057 Potassium Channel , HER
PD-118057 is a potent ether associated (hERG) potassium channel activator that shows no activity against hERG. PD-118057 inhibits the excitability of the membrane by activating the hERG channel. PD-118057 is a potential ...
T35336 Furosemide sodium Frusemide Sodium,Lasix Na-K-Cl cotransporter
Furosemide sodium (Frusemide Sodium) is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2. Furosemide sodium is also a GABAA receptors antagonist and displays 100-fold selectivity ...
T28191 NP-252 NP252
NP-252 is a calcium channel antagonist potentially for the treatment of angina pectoris and congestive heart failure.
T33805 OPC 18692 OPC-18692,OPC18692
OPC 18692 is a metabolite of Vesnarinone, a positive inotropic drug developed for congestive heart failure.
T26423 A 58365 B A-58365 B,A58365 B
A 58365 B, an angiotensin converting enzyme (ACE) inhibitor isolated from Streptomyces chromofuscus, is used for the treatment of congestive heart failure and hypertension.
T26422 A 58365 A A 58365A,A58365A,A-58365A
A 58365 A, an angiotensin converting enzyme (ACE) inhibitor isolated from Streptomyces chromofuscus, is used for the treatment of congestive heart failure and hypertension.
T28309 PD 113413 PD-113413,PD113413
PD 113413 is a metabolite of quinapril, an angiotensin-converting enzyme inhibitor for the treatment of hypertension and congestive heart failure.
T13599 Benzofurodil CB4091,Benfurodil,Eudilat Others
Benzofurodil is cardiotonic used for the chronic treatment of congestive heart failure.
T28485 Quinaprilat hydrate Quinaprilat,CI-928,CI 928,BRN 5653070
Quinaprilat is the active metabolite of quinapril, an angiotensin-converting enzyme inhibitor used in the treatment of congestive heart failure and hypertension.
T30501 BMS-193884 BMS193884,BMS 193884
BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.
T29995 Amisometradine Aminoisometradin,Aminoisometradine,Rolicton
Amisometradine is a diuretic which may be used in the treatment of congestive heart failure.
T33711 Nolomirole CHF1025,CHF-1025,CHF 1025
Nolomirole is a dopamine receptor agonist that reduces symptoms of congestive heart failure caused by monoclinine.
T34107 Polythiazide P2525,NSC-108161,NSC 108161,P-2525,NSC108161
Polythiazide (NSC-108161, P-2525) is used to treat fluid retention (edema) caused by a variety of causes, including congestive heart failure, severe liver disease (cirrhosis), kidney disease, or steroid or hormonal medic...
T30956 CK 3197 CK3197,CK-3197
CK 3197 is a selective positive inotropic agent for the treatment of congestive heart failure. It has hemodynamic and myocardial energetic effects.
T30955 CK 2289 CK-2289,CK2289
CK 2289 is an inhibitor of type III cyclic 3'5' -adenosine monophosphate phosphodiesterase with potential use in the treatment of congestive heart failure.
T11609 ICI 153110 Others
ICI 153110 is an orally active phosphodiesterase inhibitor with both inotropic and vasodilating properties. It is designed for the treatment of congestive cardiac failure.
T71205 Fosinopril-d7 sodium salt
Fosinopril-d7 is intended for use as an internal standard for the quantification of fosinopril by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme inhibitor fosinoprilat. Oral administratio...
T6444 Cilazapril Monohydrate Ro 31-2848 monohydrate,Justor RAAS
Cilazapril Monohydrate (Justor) is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.
T33600 Naxifylline CVT 124,CVT-124,CVT124,BG9719
Naxifylline is an A1 adenosine receptor antagonist that promotes urine volume to prevent the decline in renal function observed during diuretic therapy for the treatment of edema associated with congestive heart failure.
T15434 GSK2798745 TRP/TRPV Channel
GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4). It is used in research for the treatment of pulmonary edema associated wi...
T13195 Trandolapril D5 RU44570 D5 Others
Trandolapril D5 is a deuterium labeled Trandolapril. Trandolapril is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF).
T68600 Enoximone sulfoxide
Enoximone sulfoxide is a selective phosphodiesterase III (PDE3) inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. Enoximone prevents the degradation...
T80891 Urodilatin
Urodilatin, an analogue of ANF-(99-126), serves as a diuretic-natriuretic regulatory peptide with applications in the study of acute renal failure, congestive heart failure, and bronchial asthma, among other conditions [...
T62992 Trandolapril hydrochloride
Trandolapril (RU44570) hydrochloride is a non-mercapto precursor compound that is hydrolysed to active diacetyl (Trandolapril hydrochlorideat). Trandolapril hydrochloride has been studied in hypertension and congestive h...
T63425 Spirapril hydrochloride
Spirapril (SCH 33844) hydrochloride is a potent inhibitor of angiotensin-converting enzyme (ACE) and is an orally active prodrug of spiripril. Spirapril hydrochloride can be used to study hypertension and congestive hear...
T33851 Ozolinone W 3282,W3282,W-3282
Ozolinone is an active metabolite of etozoline which acts as a loop diuretic --- a diuretic that acts at the ascending limb of the loop of Henle in the kidney. Loop diuretics are primarily used in medicine to treat hyper...
T79913 GRK2 Inhibitor 2
GRK2 Inhibitor 2 (Compound 8h), with an IC50 of 19 nM for GRK2 and 137 nM for Aurora-A, enhances β-AR-mediated cAMP accumulation in GRK2-overexpressing HEK293 cells. It is utilized in congestive heart failure (HF) resear...
T76357 Neuropeptide Y (18-36) (porcine)
Neuropeptide Y (18-36) (porcine) acts as a competitive antagonist of the neuropeptide Y (NPY) cardiac receptor, effectively blocking the attachment of I-NPY to cardiac ventricular membranes. Its action is concentration-d...
T70990 ADMA-d6
NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synt...
T60383 Captopril hydrochloride
Captopril (SQ 14225) hydrochloride is an antihypertensive agent that is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor with IC 50 of 0.025 μM and has been widely used for rese...
T68616 Pentoprilat
Pentoprilat is a member of a series of l-glutarylindoline-2(S)-carboxylic acid derivatives. Pentopril was evaluated as an inhibitor of a cell-free preparation of angiotensin-converting enzyme (ACE) isolated from rabbit l...
T69600 Spermidine-d6
Spermidine-d6 is intended for use as an internal standard for the quantification of spermidine by GC- or LC-MS. Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 µ...

Compounds

Trandolapril
T5329
Synonym:
Target: Angiotensin-converting Enzyme (ACE)
Captopril
T1462
Synonym: SQ 14225,SQ-14534,SA333
Target: RAAS
Carvedilol phosphate hemihydrate
T0342
Synonym: Carvedilol phosphate,BM 14190 (phosphate hemihydrate)
Target: VEGFR, Others, Potassium Channel, LDL, Integrin, Gap Junction Protein, NADPH, Adrenergic Receptor, Autophagy
Nebivolol hydrochloride
T0154
Synonym: R 065824 hydrochloride,Nebivolol HCl,R-65824
Target: Apoptosis, Adrenergic Receptor
Imazodan hydrochloride
T27596
Synonym: Imazodan HCl,CI 914,CI-914,CI914
Target:
Imazodan
T71744
Synonym:
Target:
(Rac)-Naxifylline
T33600L
Synonym: (Rac)-Naxifylline((Rac)-166374-49-8)
Target: Others
Moexipril hydrochloride
T6595
Synonym: Moexipril HCl,RS-10085,SPM 925,CI-925
Target: Apoptosis, RAAS
Levocarnitine propionate hydrochloride
T1182
Synonym: Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,ST-261
Target: Histamine Receptor
Quinapril hydrochloride
T0805
Synonym: CI-906,PD-109452-2,Quinapril HCl
Target: RAAS
Enoximone
T8462
Synonym:
Target: PDE
(Rac)-Daglutril
T27119L
Synonym: SLV 306 acetic acid,2-((3S)-3-(1-(2-(ethoxycarbonyl)-4-phenylbutyl)cyclopentane-1-carboxamido)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid
Target: Others
Levosimendan
T2530
Synonym: OR1259,OR1855
Target: Potassium Channel, PDE, Carbonic Anhydrase, Autophagy
PD-118057
T16444
Synonym:
Target: Potassium Channel, HER
Furosemide sodium
T35336
Synonym: Frusemide Sodium,Lasix
Target: Na-K-Cl cotransporter
NP-252
T28191
Synonym: NP252
Target:
OPC 18692
T33805
Synonym: OPC-18692,OPC18692
Target:
A 58365 B
T26423
Synonym: A-58365 B,A58365 B
Target:
A 58365 A
T26422
Synonym: A 58365A,A58365A,A-58365A
Target:
PD 113413
T28309
Synonym: PD-113413,PD113413
Target:
Benzofurodil
T13599
Synonym: CB4091,Benfurodil,Eudilat
Target: Others
Quinaprilat hydrate
T28485
Synonym: Quinaprilat,CI-928,CI 928,BRN 5653070
Target:
BMS-193884
T30501
Synonym: BMS193884,BMS 193884
Target:
Amisometradine
T29995
Synonym: Aminoisometradin,Aminoisometradine,Rolicton
Target:
Nolomirole
T33711
Synonym: CHF1025,CHF-1025,CHF 1025
Target:
Polythiazide
T34107
Synonym: P2525,NSC-108161,NSC 108161,P-2525,NSC108161
Target:
CK 3197
T30956
Synonym: CK3197,CK-3197
Target:
CK 2289
T30955
Synonym: CK-2289,CK2289
Target:
ICI 153110
T11609
Synonym:
Target: Others
Fosinopril-d7 sodium salt
T71205
Synonym:
Target:
Cilazapril Monohydrate
T6444
Synonym: Ro 31-2848 monohydrate,Justor
Target: RAAS
Naxifylline
T33600
Synonym: CVT 124,CVT-124,CVT124,BG9719
Target:
GSK2798745
T15434
Synonym:
Target: TRP/TRPV Channel
Trandolapril D5
T13195
Synonym: RU44570 D5
Target: Others
Enoximone sulfoxide
T68600
Synonym:
Target:
Urodilatin
T80891
Synonym:
Target:
Trandolapril hydrochloride
T62992
Synonym:
Target:
Spirapril hydrochloride
T63425
Synonym:
Target:
Ozolinone
T33851
Synonym: W 3282,W3282,W-3282
Target:
GRK2 Inhibitor 2
T79913
Synonym:
Target:
Neuropeptide Y (18-36) (porcine)
T76357
Synonym:
Target:
ADMA-d6
T70990
Synonym:
Target:
Captopril hydrochloride
T60383
Synonym:
Target:
Pentoprilat
T68616
Synonym:
Target:
Spermidine-d6
T69600
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T3212 Digoxigenin Others
Digoxigenin, a therapeutic drug belonging to the group of cardiac glycosides, is widely used in the management of congestive heart failure and other cardiac diseases
T1694 Oxypurinol Oxipurinol ROS , Xanthine Oxidase , Endogenous Metabolite
Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure.
T1670 Lanatoside C Cedilanid,Ceglunate,Isolanid ATPase , Virus Protease , Autophagy
Lanatoside C (Ceglunate) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Lanatoside C can be used orally or by the intrav...
T8183 Deslanoside Desacetyllanatoside C,Deacetyllanatoside C ATPase , Drug Metabolite
Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...
T29599 Acetyldigitoxin Acylanide
Acetyldigitoxin is a derivative of lanatoside A or of DIGITOXIN and can be used for fast digitalization in congestive heart failure.
TargetMol