anticonvulsant

Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that suppresses HDAC1 activity and induces HDAC2 degradation, exhibiting oral bioavailability. Valproic Acid activates Notch1 signalling and inhibits the proliferation of small cell lung carcinoma cells, making it applicable for research into epilepsy and bipolar disorder.

Cyclohexanecarboxylic acid is a flavouring ingredien

Epoxylinalool (2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran) is a naturally occurring monoterpene alcohol widely used in the production of perfumes and flavors.

(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural compound derived from the roots and rhizomes of Notopterygium incisum.

Alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpenoid natural product extracted from frankincense, exhibiting anticonvulsant and anticancer effects, and in animals, it prevents and reduces Alzheimer's disease markers, making it valuable for Alzheimer's disease research.

Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.

Isovaleramide (3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, which can inhibit the liver alcohol dehydrogenases.

Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GABA analog with neuroprotective, anticonvulsant, and antihypertensive activity.

2-Acetonaphthone (beta-Naphthyl methyl ketone) is a fragrance, anticonvulsant, and antimicrobial agent. It has an onion type flavor and a sulfurous type odor.

1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic acid, a known anticonvulsant.

(S)-(+)-Carvone is a compound that occurs naturally in several foods and has anticonvulsant activity.

1H-pyrazole (1,2-Diazole), is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic, anti-inflammatory, antipyretic, antiarrhythmic, tranquilizing, muscle relaxing, psychoanaleptic, anticonvulsant, monoamineoxidase inhibiting, antidiabetic and antibacterial activities.

Tricaprilin (Glycerol Tri-n-octanoate) is used in study for patients with mild to moderate Alzheimer's disease. Tricaprilin also has a role as an anticonvulsant and a plant metabolite.

Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one), an extract from medicinal plants such as P. Incarnata, can be used as an anticonvulsant and is also a common flavoring.

4(3H)-Quinazolinone (4-Hydroxyquinazoline) is a chemically synthesized masonry block, a biologically active nitrogen heterocyclic compound. It possesses various biological properties such as antibacterial, antifungal, anticonvulsant, anti-inflammatory, anti-HIV, anticancer and pain relieving activities.

Olivetolic acid (OLA) is a precursor of cannabinoids from Cannabis sativa and has shown anticonvulsant activity in a mouse model of Dravet syndrome.Olivetolic acid has potential antimicrobial activity.

Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, and anticonvulsa

Paxilline is an indole alkaloid mycotoxin from *Penicillium paxilli*, acting as a potent BK channel inhibitor via an almost exclusively closed-channel block mechanism. Paxilline possesses significant anticonvulsant activity.

Zapotin is a natural polyhydroxylated flavonoid that inhibits K562 cells, E. coli, and HIV-1 RT RNase H, exhibiting antioxidant, antiviral, antibacterial, anticonvulsant, anticancer, anxiolytic, antifungal, and antidepressant-like activities.

Bicuculline is an alkaloid extracted from Corydalis decumbens, acting as a competitive antagonist of the neurotransmitter GABAA receptor (IC50 = 2 μM). It also blocks Ca2+-activated potassium (SK) channels and inhibits slow afterhyperpolarization (slow AHP). Bicuculline has anticonvulsant effects and is commonly used to establish mouse seizure models.

11-Ketoetiocholanolone is a metabolite of testosterone's excreted metabolite, etiocholanolone, and exhibits anticonvulsant activity[1][2].

Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 microM (+)-eudesmin can induce neurite outgrowth and enhance nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways.

Neophytadiene is a diterpene compound extracted from Turbinaria ornate, with anti-inflammatory, antidepressant, anxiolytic-like, anticonvulsant, antioxidant, and cardioprotective effects. It inhibits LPS-induced inflammation in RAW 264.7 macrophages and Sprague-Dawley rats and can be used in neurological disease research.

Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutamic acid in the brain, and it up-regulates expressions of GAD 65, may be a promising future the