anti-rheumatic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0767	Sulfapyridine	Sulfidine,Sulfidin,2-Sulfapyridine	Antibacterial , Antibiotic , Autophagy
	Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.		Antibacterial , Antibiotic , Autophagy
T7882	Indomethacin farnesil	Infree	Others , COX , Autophagy
	Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).		Others , COX , Autophagy
T2179	Triptolide	PG490,NSC 163062	Apoptosis , Mdm2 , HSP , NF-κB
	Triptolide (PG490) belongs to the tricyclic diterpenoid group of natural products and is an inhibitor of NF-κB activation. Triptolide exhibits immunosuppressive, anti-rheumatic, anti-inflammatory, anti-proliferative and ...		Apoptosis , Mdm2 , HSP , NF-κB
T20168	Aurothiomalate sodium	Myocrisin,Myocrisine,Miochrysin,Sodium aurothiomalate,Myochrysine,gold sodium thiomalate	Others , PKC
	Sodium aurothiomalate is a gold compound that is used for its immunosuppressive anti-rheumatic effects. Aurothiomalate sodium (Miochrysin) is a potent and selective inhibitor of oncogenic PKC-ι signaling. Aurothiomalate ...		Others , PKC
T4S0536	Bullatine A		Apoptosis , P2X Receptor
	1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the treatment of neurodegenerative diseases such as arthritis.		Apoptosis , P2X Receptor
T0855	(R)-Naproxen		COX
	(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis...		COX
T2967	Stigmasterol	Stigmasterin,beta-Stigmasterol	MMP , Endogenous Metabolite
	Stigmasterol (Stigmasterin) is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol has been focused on the ch...		MMP , Endogenous Metabolite
T4S1057	Tripdiolide		IL Receptor , TNF
	Tripdiolide has cytotoxic, and anti-rheumatic activities, it suppresses pro-inflammatory gene expression, may be effective therapy for lupus nephritis.		IL Receptor , TNF
T30112	AR 17048	AR17048,AR-17048
	AR-17048 is a potential anti-rheumatic drug.
T69459	Cistifolin
	Cistifolin is an integrin-dependent cell adhesion blocker from the anti-rheumatic herbal drug, gravel root
T28916	TAK-603	TAK603,TAK 603
	TAK-603 is an anti-rheumatic drug and is also anti-inflammatory compound. It selectively suppresses Th1 cytokine production and inhibits the progression of adjuvant arthritis.
T27382	FR-217840
	FR-217840, a novel matrix metalloproteinase inhibitor, successfully suppresses joint destruction and suggest that FR217840 may have potential as a novel anti-rheumatic drug.
T13155	Tiaprofenic acid D3		Others
	Tiaprofenic acid D3 is a deuterium-labeled Tiaprofenic acid. Tiaprofenic acid is a nonsteroidal anti-inflammatory drug and treatment of rheumatic diseases.		Others
T25959	Pipebuzone	LD-4644,LD 4644,LD4644,Pipebuzonum
	Pipebuzone is an anti-inflammatory, antipyretic and analgesic drug used in the treatment of various rheumatic diseases. It is well tolerated clinically and pathologically and has a reliable anti-inflammatory effect.
T25911	Oxycinchophen	Magnophenyl,Sintofene,Reumartril,Chinoxone
	Oxycinchophen is a quinoline-like organic, anti-rheumatic compound. It has been used to study P- selectin antagonistic activity, DHOD inhibitory activity, and the effects of anti-inflammatory drugs on vascular smooth mus...
TN5498	6,7,4'-Trihydroxyflavanone		Others
	6,7,4'-Trihydroxyflavanone possesses various pharmacological activities, including anti-rheumatic, anti-ischemic, anti-inflammatory, anti-osteoclastogenic, and protective effects against METH-induced deactivation of T ce...		Others
T62913	Piroxicam cinnamate
	Piroxicam cinnamate (Cinnoxicam) is a cyclooxygenase (COX) inhibitor that exhibits anti-inflammatory effects. piroxicam cinnamate can be used to study inflammatory degenerative bone and joint diseases, rheumatic diseases...
T37419	Zetomipzomib
	KZR-616, a first-in-class inhibitor of the immunoproteasome, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. KZR-616 has the potential f...