anti-hyperglycemic

Nomilin is naturally occurring triterpenoids, have immunomodulatory activity.

1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.

syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehyde moderately inhibits COX-2 activity with an IC50 of 3.5 μg mL. Anti-hyperglycemic and anti-inflammatory activities.

Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential.

Borapetoside E has anti-hyperglycemic activity, it can significantly reduce serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice.

Demethylisoencecalin (6-Acetyl-5-hydroxy-2,2-dimethyl-2H-1-benzopyran) has anti-hyperglycemic activity.

5-O-Coumaroylquinic acid (3-O-Coumaroylquinic acid), exhibits significant inhibition of PTP1B and a concentration-dependent inhibitory effect on α-glucosidase, thereby demonstrating anti-hyperglycemic properties. Additionally, this compound enhances glucose uptake and inhibits PTP1B in vitro, emphasizing its potential therapeutic applications in glucose regulation.

Deacetylescin Ia (compound 12) is an anti-hyperglycemic deacetylated saponin extracted from de-bittered Ginkgo biloba leaves by deacetylation at position C-22. In mice glucose tolerance tests, Deacetylescin Ia (100mg kg) demonstrated an ability to inhibit the increase in blood sugar levels.