Search Result

Search Results for " activation "

Targets

NF-κB DNA/RNA Synthesis

993

Compounds

287

Natural Products

2638

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T9656	AP-1/NF-κB activation inhibitor 1		NF-κB , DNA/RNA Synthesis
	AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation in...		NF-κB , DNA/RNA Synthesis
T8705	BOT-64		IκB/IKK
	BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole compound		IκB/IKK
T22115	SM-7368		NF-κB
	The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.		NF-κB
T80543	STE-MEK1(13)	ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂	ERK
	STE-MEK1(13), a cell-permeable ERK1/2 inhibitor with IC50 values ranging from 13 to 30 μM, impedes the phosphorylation of ERK1/2, as demonstrated in studies [1] [2].		ERK
T5697	BMS-1166		PD-1/PD-L1
	BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.		PD-1/PD-L1
T15485	HJC0197		cAMP , Ras
	HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).		cAMP , Ras
T6594	MNS		Syk , Src , p97
	MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.		Syk , Src , p97
T11095L	DREADD agonist 21		5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
	DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).
T13176	TNO155	Batoprotafib	Phosphatase
	TNO155 is a protein tyrosine phosphatase (PTP) non-receptor type 11 (SHP2; src homology region 2 domain phosphatase; PTPN11) inhibitor(IC50 : 0.011 µM),with potential antineoplastic activity.		Phosphatase
T22012	7BIO		FLT , DYRK , Aurora Kinase
	7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.		FLT , DYRK , Aurora Kinase
T8719	SC99		Apoptosis , JAK , STAT
	SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti...		Apoptosis , JAK , STAT
T9962	Mepolizumab	SB 240563	IL Receptor
	Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis.		IL Receptor
T20759	XRP44X	XRP-44-X,XRP 44X,XRP-44X,XRP 44 X	Ras
	XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.		Ras
T8978	DD1	3,3'-Diamino-4'-methoxyflavone,HUN85111	Proteasome
	DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.		Proteasome
T20789	S-23	(S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide,S23	Androgen Receptor
	S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal ve...		Androgen Receptor
T4205	AG-494	Tyrphostin AG-494,AG 494,Tyrphostin B48	EGFR , CDK
	AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.		EGFR , CDK
T6379	AMG 517	AMG517,AMG-517	TRP/TRPV Channel
	AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.		TRP/TRPV Channel
T77124	Osocimab	BAY 1213790	FXR
	Osocimab (BAY 1213790) is a potent anti-FXIa antibody with a Ki value of 2.4 nM and an EC50 value of 0.2 nM.Osocimab may reduce thrombosis through FXI inhibition.Osocimab is often used as an XI factor inhibitor, has an i...		FXR
T11234	ESI-08		cAMP
	ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.		cAMP
T22119	NS3694		Apoptosis
	NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.		Apoptosis
T1897	MDL-29951		NMDAR , iGluR
	MDL-29951 is a novel glycine antagonist of NMDA receptor activation.		NMDAR , iGluR
T32613	LCB 03-0110 dihydrochloride		Src
	LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and T...		Src
T12834	Saroglitazar Magnesium		Others
	Saroglitazar Magnesium is a novel peroxissome proliferator-activated receptor (PPAR) agonist with significant activation activity against PPARα (EC50 0.65pM) and moderate activation against PPARγ (EC50 3 nM).		Others
T30077	Anisperimus	LF 150195,LF-150195,LF 15-0195,LF-15-0195,LF15-0195	Caspase
	Anisperimus (LF 15-0195) is an immunosuppressant that enhances activation-induced T-cell death by promoting caspase-8 and caspase-10 activation at the DISC level, and prevents CNS autoimmunity by promoting the developmen...		Caspase
T7676	LSKL, Inhibitor of Thrombospondin TSP-1 acetate	LSKL, Inhibitor of Thrombospondin TSP-1	TGF-beta/Smad
	LSKL, Inhibitor of Thrombospondin TSP-1 acetate is activation of TGF-β .		TGF-beta/Smad
T15247	ESI-05	NSC 116966	cAMP
	ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.		cAMP
T3626	Acalabrutinib	ACP-196	BTK
	Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre...		BTK
T15633	JW74		Wnt/beta-catenin
	JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).		Wnt/beta-catenin
T10977	DCEBIO		Potassium Channel
	DCEBIO stimulates the secretion of Cl- through the activation of the hIK1 K + channel and the activation of the apical Cl- conductance. DCEBIO is a derivative of 1-EBIO and a very strong activator of Cl- secretion by T84...		Potassium Channel
T1237	Azathioprine	BW 57-322	Apoptosis , GPR , Rho
	Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.		Apoptosis , GPR , Rho
T9156	CDC25B-IN-2		Phosphatase , mTOR
	BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.		Phosphatase , mTOR
T8655	SR-717		STING
	SR-717 is a cGAMP analog, a non-nucleoside STING agonist that induces a "closed" activation conformation of STING. SR-717 has antitumor activity and promotes activation of immune cells and cross-presentation of antigens.		STING
T77628	Bisindolylmaleimide III		PKC
	Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6 protein kinase 1 upon activation of these kinases.		PKC
T9853	STING activator Compound 53		STING
	STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons...		STING
T22089	HPI 1		Hedgehog/Smoothened
	HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced a...		Hedgehog/Smoothened
T1893	Parmodulin 2	ML 161	Protease-activated Receptor
	Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...		Protease-activated Receptor
T9266	Fatostatin		Lipid , Fatty Acid Synthase
	Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.		Lipid , Fatty Acid Synthase
TQ0305	CID-2858522		NF-κB
	CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).		NF-κB
T72112	Clozapine N-oxide dihydrochloride		AChE
	Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of human muscarinic design receptors (DREADDs) that crosses the blood-brain barrier.Clozapine N-oxide dihydrochloride induces activation of DR...		AChE
T28865	STAT3-IN-B9	STAT3 IN B9,B9	STAT
	STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.		STAT
T23497	UK 78282 hydrochloride		Potassium Channel
	UK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.		Potassium Channel
T9734	InhA-IN-2		CDK
	InhA-IN-2 directly inhibits InhA and does not require activation by the catalase peroxidase KatG.		CDK
T4459	PK11000		DNA Alkylator/Crosslinker
	PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.		DNA Alkylator/Crosslinker
T12705	Reparixin L-lysine salt	Repertaxin L-lysine salt	CXCR
	Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.		CXCR
T19651	Isoflurane	HSDB-8057,Forane,HSDB 8057,HSDB8057,Terrell	Others
	Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation.		Others
T13918	Tecalcet Hydrochloride	R-568 hydrochloride,R-568 (hydrochloride)	CaSR
	Tecalcet Hydrochloride (R-568 hydrochloride) is an allosteric and positive modulator of the calcium-sensing receptor(CaSR). Tecalcet Hydrochloride increases the sensitivity to the activation of extracellular Ca2+.		CaSR
T18902	6-FAM	6-Carboxyfluorescein	Others
	6-Carboxyfluorescein (6-FAM) contains a carboxylic acid functional group, facilitating reactions with primary amines through carbodiimide activation.		Others
T12192	NCGC00229600		Others , TSH Receptor
	NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.		Others , TSH Receptor
T13683	Epsilon-momfluorothrin	Momfluorothrin, (Z,1R,3R)-	Others
	Epsilon-momfluorothrin (Momfluorothrin, (Z,1R,3R)-), a type I synthetic pyrethroid insecticide, exerts its insecticidal properties and triggers activation of the constitutive androstane receptor (CAR). Notably, its admin...		Others
T1772	MDK83190	Apoptosis Activator 2	Apoptosis , Caspase
	MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .		Apoptosis , Caspase

Compounds

AP-1/NF-κB activation inhibitor 1

T9656

Synonym:

Target: NF-κB, DNA/RNA Synthesis

Synonym: ERK Activation Inhibitor Peptide,Ste-MPKKKPTPIQLNP-NH₂

Target: Syk, Src, p97

DREADD agonist 21

T11095L

Synonym:

Target: 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor

TNO155

T13176

Synonym: Batoprotafib

Target: FLT, DYRK, Aurora Kinase

SC99

T8719

Synonym:

Target: Apoptosis, JAK, STAT

Synonym: XRP-44-X,XRP 44X,XRP-44X,XRP 44 X

Target: Ras

DD1

T8978

Synonym: 3,3'-Diamino-4'-methoxyflavone,HUN85111

Target: Proteasome

S-23

T20789

Synonym: (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide,S23

Target: Androgen Receptor

AG-494

T4205

Synonym: Tyrphostin AG-494,AG 494,Tyrphostin B48

Target: EGFR, CDK

AMG 517

T6379

Synonym: AMG517,AMG-517

Target: TRP/TRPV Channel

LCB 03-0110 dihydrochloride

T32613

Synonym:

Target: Src

Saroglitazar Magnesium

Synonym: LF 150195,LF-150195,LF 15-0195,LF-15-0195,LF15-0195

Target: Caspase

LSKL, Inhibitor of Thrombospondin TSP-1 acetate

T7676

Synonym: LSKL, Inhibitor of Thrombospondin TSP-1

Target: TGF-beta/Smad

Target: Wnt/beta-catenin

DCEBIO

T10977

Synonym:

Target: Potassium Channel

Azathioprine

T1237

Synonym: BW 57-322

Target: Apoptosis, GPR, Rho

CDC25B-IN-2

T9156

Synonym:

Target: Phosphatase, mTOR

Bisindolylmaleimide III

T77628

Synonym:

Target: PKC

STING activator Compound 53

Target: Hedgehog/Smoothened

Parmodulin 2

T1893

Synonym: ML 161

Target: Protease-activated Receptor

Fatostatin

T9266

Synonym:

Target: Lipid, Fatty Acid Synthase

Clozapine N-oxide dihydrochloride

Synonym: STAT3 IN B9,B9

Target: STAT

UK 78282 hydrochloride

T23497

Synonym:

Target: Potassium Channel

Target: DNA Alkylator/Crosslinker

Reparixin L-lysine salt

T12705

Synonym: Repertaxin L-lysine salt

Target: CXCR

Isoflurane

T19651

Synonym: HSDB-8057,Forane,HSDB 8057,HSDB8057,Terrell

Target: Others

Tecalcet Hydrochloride

T13918

Synonym: R-568 hydrochloride,R-568 (hydrochloride)

Target: CaSR

6-FAM

T18902

Synonym: 6-Carboxyfluorescein

Target: Others, TSH Receptor

Epsilon-momfluorothrin

T13683

Synonym: Momfluorothrin, (Z,1R,3R)-

Target: Others

MDK83190

T1772

Synonym: Apoptosis Activator 2

Target: Apoptosis, Caspase

Cat No.	Product Name	Synonyms	Targets
T5552	Methyl cinnamate		Tyrosinase , Antibacterial , AMPK
	Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.		Tyrosinase , Antibacterial , AMPK
T9352	Hydrocotarnine		Others
	hydrocotarnine is an inhibitor of Cbl.		Others
T3S2072	3-Butylidenephthalide	Butylidene phthalide,n-Butylidenephthalide	Parasite , Glucosidase
	1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitiv...		Parasite , Glucosidase
T1633	β-Carotene	Carotaben,Beta-Carotene,Provitamin A	Apoptosis , ROS , Endogenous Metabolite
	β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene...		Apoptosis , ROS , Endogenous Metabolite
T3385	Gypenoside XVII	GP-17,Gynosaponin S	Estrogen Receptor/ERR , GSK-3 , Endogenous Metabolite
	Gypenoside XVII (Gynosaponin S) confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/ARE/HO-1 and inactivation of GSK-3β pathway...		Estrogen Receptor/ERR , GSK-3 , Endogenous Metabolite
T9328	Ellagic Acid Dihydrate		P450
	Ellagic Acid Dihydrate inhibit the CYP1A1-dependent activation of benzo[a]pyrene.		P450
T19711	Desmosterol	Desmesterol,24-Dehydrocholesterol	Endogenous Metabolite
	Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation and prevents vascular inflammation and atherosclerosis.		Endogenous Metabolite
T8678	Naphthazarin	5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter...		Apoptosis
TQ0185	14-Deoxy-11,12-didehydroandrographolide	AP10,14-dehydro Andrographolide	NF-κB
	14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.		NF-κB
TN3016	4',6,7-Trimethoxyisoflavone		MMP
	4',6,7-Trimethoxyisoflavone promotes wound healing through NOX2 induction, which leads to collective migration and MMP activation.		MMP
T4037	Phorbol	4β-Phorbol,(+)-Phorbol	PKC
	Phorbol (4β-Phorbol), a plant-derived diterpene, is a tumor promoter through the activation of protein kinase C.		PKC
T5S1895	Norisoboldine	Laurelliptine,(+)-Laurelliptine	MAPK , Adenosine Receptor
	1. Norisoboldine ((+)-Laurelliptine) might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisobo...		MAPK , Adenosine Receptor
T5S1261	Methylophiopogonanone B		Ras
	1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.		Ras
TN2063	Physalin B	NSC-287088	Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD
	Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B amel...		Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD
T40660	Kansuinine B		IL Receptor , SARS-CoV
	Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research.		IL Receptor , SARS-CoV
TN1131	Handelin		NF-κB , Immunology/Inflammation related
	Handelin has anti-inflammatory activity by inhibiting NF-κB activation and pro-inflammatory cytokine productions.		NF-κB , Immunology/Inflammation related
T23735	Jamaicin	An-Co-A4,AnCoA-4,An Co A4,AnCoA4	Calcium Channel
	Jamaicin (AnCoA4), an isoflavone derived from the chickweed plant, is an inhibitor of the STIM1-Orai1 channel that blocks calcium influx, reduces its interaction with STIM1, and inhibits T-cell activation.		Calcium Channel
T10117	3'-O-Acetylhamaudol		Others
	3'- O- Acetylhamaudol, isolated from the roots of Angelica japonica, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation.		Others
T2854	Phillyrin	Forsythin	P450 , Influenza Virus , AMPK
	Phillyrin (Forsythin) is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activ...		P450 , Influenza Virus , AMPK
T6S1367	Procyanidin B2	Proanthocyanidin B2	Reactive Oxygen Species , NOD
	Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ...		Reactive Oxygen Species , NOD
TMS2171	(±)-Naringenin	Salipurpol,Naringenine,Naringenin	Potassium Channel
	(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes.		Potassium Channel
T3806	Kaempferide	Kaempferol 4'-O-methyl ether,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Influenza Virus , Antibacterial , Autophagy
	kaempferide (4'-Methylkaempferol) inhibits the proliferation of native and estrogen receptor beta overexpressing colon cancer cells through a mechanism not mediated by ligand binding dependent estrogen receptor activatio...
TN2346	Mogrol		ERK , AMPK , STAT
	Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.		ERK , AMPK , STAT
T9503	PHYTOSPHINGOSINE		Apoptosis
	Phytosphingosine is a phospholipid with anticancer properties. In cancer cells, Phytosphingosine induces cell apoptosis through activation of caspase 8 and translocation of Bax.		Apoptosis
T5798	Euphorbia Factor L2	euphorbiafactor L2	Apoptosis , NF-κB
	Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.		Apoptosis , NF-κB
T8092	Taurohyodeoxycholic acid sodium salt	Sodium taurohyodeoxycholate hydrate	Caspase
	Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.		Caspase
T3399	Psoralidin		Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial
	Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties.
T5079	Adenosine 5'-diphosphate sodium salt	Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others , Endogenous Metabolite
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is...		Others , Endogenous Metabolite
T2823	Crocin	Gardenia Yellow,Alpha-Crocin	Others
	Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne...		Others
TN1110	Shanziside	Shanzhiside	IL Receptor
	Shanziside (Shanzhiside) has immunosuppressive activity, it shows significant inhibition of IL-2 secretion by phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood...		IL Receptor
TN1933	Mitraphylline		IL Receptor , TNF , NF-κB
	Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-mediated activation of primary human neutrophils.		IL Receptor , TNF , NF-κB
T5S0168	Atractylenolide II	2-Atractylenolide,Asterolide	Apoptosis , ERK , p38 MAPK , Akt , STAT
	1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK and Akt inactivation, p53 dependent.		Apoptosis , ERK , p38 MAPK , Akt , STAT
TN1096	Ginsenoside Ra1		Others , Tyrosine Kinases
	Ginsenoside Ra1 is a component from ginseng. Ginsenoside Ra1 shows significant inhibitory effects on protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation (H/R).		Others , Tyrosine Kinases
T3843	Pinosylvin	3,5-stilbenediol,5-Styrylresorcinol	Apoptosis , Others , Antibacterial , Autophagy
	Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.		Apoptosis , Others , Antibacterial , Autophagy
TN1031	Poricoic acid B		Others
	Poricoic acid B shows inhibitory activity against TPA-induced ear inflammatory oedema, it also shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-te...		Others
T6S1587	Notoginsenoside R2	20(S)-Notoginsenoside R2,Ginsenoside Ng-R2	Others , Nrf2
	Notoginsenoside R2 (20(S)-Notoginsenoside R2) has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways.		Others , Nrf2
TQ0169	Inulicin	1-O-Acetylbritannilactone	FAK , NF-κB , COX , Src
	Inulicin (1-O-Acetylbritannilactone), an active compound isolated from Inula Britannica L, inhibits VEGF-mediated activation of Src and FAK.		FAK , NF-κB , COX , Src
T5S1097	Neferine	(R)-1,2-Dimethoxyaporphine,(-)-Neferine	Apoptosis , NF-κB , Autophagy
	1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to a...		Apoptosis , NF-κB , Autophagy
T3S0872	Paederoside		Antiviral , HBV
	1. Paederoside is a potent deterrent against the beetle was isolated from the aphid . 2. Paederoside displays high anti-tumor promoting activity against the Epstein-Barr virus activation.		Antiviral , HBV
T3000	Magnolol	NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol	NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy
	Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
T13803	N-Oleoyl glycine		Cannabinoid Receptor , Akt , Endogenous Metabolite , PPAR
	N-Oleoyl Glycine, a Lipoamino Acid, Stimulates Adipogenesis Associated With Activation of CB1 Receptor and Akt Signaling Pathway in 3T3-L1 Adipocyte		Cannabinoid Receptor , Akt , Endogenous Metabolite , PPAR
T4S1615	Sanggenon C	Sanggenone C	NF-κB
	1. Sanggenon C (Sanggenone C) inhibits tumor cellular proteasomal activity and cell viability, via induction of cell cycle arrest and cell death , inhibiting the proteasome function. 2. Sanggenon C and O inhibited NO pro...		NF-κB
T2947	Indole-3-carbinol	I3C,3-Indolemethanol,Indole-3-Methanol	E1/E2/E3 Enzyme , NF-κB , Aryl Hydrocarbon Receptor , Endogenous Metabolite , p53
	Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.
TN1136	Procyanidin A1	Proanthocyanidin A1	LDL , Calcium Channel , PKC
	Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells.		LDL , Calcium Channel , PKC
T6429	Caffeic Acid Phenethyl Ester	Phenylethyl Caffeate,CAPE	Apoptosis , NF-κB
	Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...		Apoptosis , NF-κB
T10383	Asatone		NF-κB
	Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK, and p38) pathways.		NF-κB
T3844	Deltonin		ERK , Others , Akt , Endogenous Metabolite
	Deltonin has an inhibition of ERK1/2 and AKT activation. Deltonin shows cytotoxicity against human HepG2 cells (IC50: 7.66 μM), mouse C26 cells (IC50: 1.22 μM), and human MDA-MB-231 cells (IC50: 1.58 μM).		ERK , Others , Akt , Endogenous Metabolite
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T5S2358	Dehydrocorydaline	Dehydrocorydalin,13-Methylpalmatine	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
TN6750	2-tert-Butyl-1,4-benzoquinone		Nrf2
	2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its negative regulator Keap1 in RAW264.7 cells.		Nrf2
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Natural Products

Methyl cinnamate

T5552

Synonym:

Target: Tyrosinase, Antibacterial, AMPK

3-Butylidenephthalide

T3S2072

Synonym: Butylidene phthalide,n-Butylidenephthalide

Target: Parasite, Glucosidase

β-Carotene

T1633

Synonym: Carotaben,Beta-Carotene,Provitamin A

Target: Apoptosis, ROS, Endogenous Metabolite

Gypenoside XVII

T3385

Synonym: GP-17,Gynosaponin S

Target: Estrogen Receptor/ERR, GSK-3, Endogenous Metabolite

Ellagic Acid Dihydrate

Synonym: Desmesterol,24-Dehydrocholesterol

Target: Endogenous Metabolite

Naphthazarin

T8678

Synonym: 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ

Target: Apoptosis

14-Deoxy-11,12-didehydroandrographolide

TQ0185

Synonym: AP10,14-dehydro Andrographolide

Target: NF-κB

4',6,7-Trimethoxyisoflavone

Synonym: 4β-Phorbol,(+)-Phorbol

Target: PKC

Norisoboldine

T5S1895

Synonym: Laurelliptine,(+)-Laurelliptine

Target: MAPK, Adenosine Receptor

Methylophiopogonanone B

Target: Apoptosis, NF-κB, Akt, PI3K, Nrf2, NOD

Kansuinine B

T40660

Synonym:

Target: IL Receptor, SARS-CoV

Handelin

TN1131

Synonym:

Target: NF-κB, Immunology/Inflammation related

Jamaicin

T23735

Synonym: An-Co-A4,AnCoA-4,An Co A4,AnCoA4

Target: Calcium Channel

Target: P450, Influenza Virus, AMPK

Procyanidin B2

T6S1367

Synonym: Proanthocyanidin B2

Target: Reactive Oxygen Species, NOD

(±)-Naringenin

TMS2171

Synonym: Salipurpol,Naringenine,Naringenin

Target: Potassium Channel

kaempferide

T3806

Synonym: Kaempferol 4'-O-methyl ether,Kaempferol 4'-methyl ether,4'-Methylkaempferol,4'-O-Methylkaempferol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Influenza Virus, Antibacterial, Autophagy

Mogrol

TN2346

Synonym:

Target: ERK, AMPK, STAT

Synonym: euphorbiafactor L2

Target: Apoptosis, NF-κB

Taurohyodeoxycholic acid sodium salt

T8092

Synonym: Sodium taurohyodeoxycholate hydrate

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

Adenosine 5'-diphosphate sodium salt

T5079

Synonym: Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

Crocin

T2823

Synonym: Gardenia Yellow,Alpha-Crocin

Target: IL Receptor, TNF, NF-κB

Atractylenolide II

T5S0168

Synonym: 2-Atractylenolide,Asterolide

Target: Apoptosis, ERK, p38 MAPK, Akt, STAT

Ginsenoside Ra1

TN1096

Synonym:

Target: Others, Tyrosine Kinases

Pinosylvin

T3843

Synonym: 3,5-stilbenediol,5-Styrylresorcinol

Target: Apoptosis, Others, Antibacterial, Autophagy

Synonym: 20(S)-Notoginsenoside R2,Ginsenoside Ng-R2

Target: Others, Nrf2

Inulicin

TQ0169

Synonym: 1-O-Acetylbritannilactone

Target: FAK, NF-κB, COX, Src

Neferine

T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine

Target: Apoptosis, NF-κB, Autophagy

Paederoside

T3S0872

Synonym:

Target: Antiviral, HBV

Magnolol

T3000

Synonym: NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol

Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy

N-Oleoyl glycine

T13803

Synonym:

Target: Cannabinoid Receptor, Akt, Endogenous Metabolite, PPAR

Sanggenon C

T4S1615

Synonym: Sanggenone C

Target: NF-κB

Indole-3-carbinol

T2947

Synonym: I3C,3-Indolemethanol,Indole-3-Methanol

Target: E1/E2/E3 Enzyme, NF-κB, Aryl Hydrocarbon Receptor, Endogenous Metabolite, p53

Procyanidin A1

TN1136

Synonym: Proanthocyanidin A1

Target: LDL, Calcium Channel, PKC

Caffeic Acid Phenethyl Ester

T6429

Synonym: Phenylethyl Caffeate,CAPE

Target: Apoptosis, NF-κB

Target: ERK, Others, Akt, Endogenous Metabolite

Honokiol

T3001

Synonym: NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Dehydrocorydaline

T5S2358

Synonym: Dehydrocorydalin,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

2-tert-Butyl-1,4-benzoquinone

TN6750

Synonym:

Target: Nrf2

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04962	FAP Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-04922	FAP Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-05092	LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)	Cynomolgus	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-02154	FAP Protein, Human, Recombinant (His)	Human	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-04730	LAG-3 Protein, Human, Recombinant (His)	Human	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04939	LAG-3 Protein, Human, Recombinant	Human	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPJ-00889	IL-13 Protein, Mouse, Recombinant (aa 22-131, His)	Mouse	Human Cells
	Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds...
TMPY-06074	B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
TMPJ-00890	IL-13 Protein, Mouse, Recombinant (aa 26-131, His)	Mouse	Human Cells
	Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells. IL-13 induces B cell proliferation and immunoglobin production. It contains a four helical bundle with two internal disulfide bonds...
TMPY-05322	B7-H4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
TMPY-03524	B7-H4 Protein, Human, Recombinant (His)	Human	HEK293
	V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
TMPJ-00959	B7-2 Protein, Rabbit, Recombinant (His)	Rabbit	Human Cells
	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of imm...
TMPY-06915	FAP Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPY-03759	LAG-3 Protein, Rat, Recombinant (His)	Rat	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-06525	FAP Protein, Human, Recombinant (aa 27-760, His)	Human	Baculovirus-Insect Cells
	Seprase, also known as 17 kDa melanoma membrane-bound gelatinase , Fibroblast activation protein alpha, Integral membrane serine protease and FAP, is a single-pass type II membrane protein which belongs to thepeptidase S...
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His)	Rabbit	Human Cells
	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their recep...
TMPJ-00630	B7-1 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and...
TMPJ-00632	B7-2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of imm...
TMPJ-00641	B7-2 Protein, Rhesus macaque, Recombinant (His)	Rhesus macaque	Human Cells
	T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of imm...
TMPY-03667	SLAM/CD150 Protein, Rat, Recombinant (His)	Rat	HEK293
	CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp...
TMPY-00627	SLAM/CD150 Protein, Rat, Recombinant (hFc)	Rat	HEK293
	CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp...
TMPY-05130	LAG-3 Protein, Human, Recombinant, Biotinylated	Human	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04528	LAG-3 Protein, Human, Recombinant (hFc)	Human	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-06931	LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04731	LAG-3 Protein, Human, Recombinant (mFc)	Human	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04611	LAG-3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thy...
TMPJ-01070	CD83 Protein, Human, Recombinant (hFc)	Human	Human Cells
	CD83 antigen is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells. It c...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His)	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPH-03275	Cytoglobin Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPJ-00556	B7-2 Protein, Human, Recombinant (His)	Human	Human Cells
	The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T...
TMPY-05746	LAG-3 Protein, Mouse, Recombinant	Mouse	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04612	LAG-3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-02378	14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)	Human	E. coli
	The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclamp...
TMPH-00213	Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)	Bothrops atrox	E. coli
	Inhibits fibrinogen interaction with platelets. Acts by binding to the glycoprotein IIb-IIIa receptor (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor a...
TMPJ-00555	B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	Human Cells
	The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T...
TMPY-02584	14-3-3 beta Protein, Cynomolgus, Recombinant	Cynomolgus	E. coli
	14-3-3 beta / YWHAB is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly conserved proteins that are involved in many vital cellular processes such as metabolism, protein trafficking, signal t...
TMPJ-00223	SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in...
TMPJ-01323	NTAL Protein, Human, Recombinant (His)	Human	Human Cells
	Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is invol...
TMPJ-01206	Sting Protein, Human, Recombinant (Sumo & His)	Human	E. coli
	Stimulator of Interferon Gene(Sting,TMEM173) belongs to the TMEM173 family. STING is 379 amino acids (aa) in length. It contains an N-terminal cytoplasmic region (aa 1-20), four transmembrane segments (aa 21-173), and a ...
TMPY-02377	14-3-3 eta/YWHAH Protein, Human, Recombinant (GST)	Human	E. coli
	YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on ...
TMPY-02179	14-3-3 epsilon Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co...
TMPJ-01421	LAG-3 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation a...
TMPJ-00321	LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation a...
TMPY-01016	SLAM/CD150 Protein, Human, Recombinant (His)	Human	HEK293
	CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is exp...
TMPJ-00226	SLAMF1 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, an...
TMPY-02658	B7-H4 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	V-set domain-containing T-cell activation inhibitor 1, also known as B7X, B7H4, B7S1, and VTCN1, is a single-pass type-III membrane protein belonging to the B7 family of costimulatory proteins. These proteins are express...
TMPH-02908	AICDA Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (...
TMPY-01274	14-3-3 epsilon Protein, Human, Recombinant	Human	E. coli
	YWHAE, also known as 14-3-3 epsilon, mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 epsilon / YWHAE is a member of the 14-3-3 proteins family. 14-3-3 proteins are a group of highly co...
TMPJ-00421	CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
	CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I ...
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FAP Protein, Cynomolgus, Recombinant (His)

TMPY-04962

Species: Cynomolgus

Expression System: HEK293

FAP Protein, Human, Recombinant (His), Biotinylated

TMPY-04922

Species: Human

Expression System: HEK293

LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)

TMPY-05092

Species: Cynomolgus

Expression System: HEK293

FAP Protein, Human, Recombinant (His)

TMPY-02154

Species: Human

Expression System: HEK293

LAG-3 Protein, Human, Recombinant (His)

TMPY-04730

Species: Human

Expression System: HEK293

LAG-3 Protein, Human, Recombinant

TMPY-04939

Species: Human

Expression System: HEK293

IL-13 Protein, Mouse, Recombinant (aa 22-131, His)

TMPJ-00889

Species: Mouse

Expression System: Human Cells

B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-06074

Species: Cynomolgus,Rhesus

Expression System: HEK293

IL-13 Protein, Mouse, Recombinant (aa 26-131, His)

TMPJ-00890

Species: Mouse

Expression System: Human Cells

B7-H4 Protein, Mouse, Recombinant (His)

TMPY-05322

Species: Mouse

Expression System: HEK293

B7-H4 Protein, Human, Recombinant (His)

TMPY-03524

Species: Human

Expression System: HEK293

B7-2 Protein, Rabbit, Recombinant (His)

TMPJ-00959

Species: Rabbit

Expression System: Human Cells

FAP Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06915

Species: Human

Expression System: HEK293

LAG-3 Protein, Rat, Recombinant (His)

TMPY-03759

Species: Rat

Expression System: HEK293

FAP Protein, Human, Recombinant (aa 27-760, His)

TMPY-06525

Species: Human

Expression System: Baculovirus-Insect Cells

B7-1 Protein, Rabbit, Recombinant (His)

TMPJ-00958

Species: Rabbit

Expression System: Human Cells

B7-1 Protein, Cynomolgus, Recombinant (hFc)

TMPJ-00630

Species: Cynomolgus

Expression System: Human Cells

B7-2 Protein, Cynomolgus, Recombinant (hFc)

TMPJ-00632

Species: Cynomolgus

Expression System: Human Cells

B7-2 Protein, Rhesus macaque, Recombinant (His)

TMPJ-00641

Species: Rhesus macaque

Expression System: Human Cells

SLAM/CD150 Protein, Rat, Recombinant (His)

TMPY-03667

Species: Rat

Expression System: HEK293

SLAM/CD150 Protein, Rat, Recombinant (hFc)

TMPY-00627

Species: Rat

Expression System: HEK293

LAG-3 Protein, Human, Recombinant, Biotinylated

TMPY-05130

Species: Human

Expression System: HEK293

LAG-3 Protein, Human, Recombinant (hFc)

TMPY-04528

Species: Human

Expression System: HEK293

LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-06931

Species: Human

Expression System: HEK293

LAG-3 Protein, Human, Recombinant (mFc)

TMPY-04731

Species: Human

Expression System: HEK293

LAG-3 Protein, Mouse, Recombinant (hFc)

TMPY-04611

Species: Mouse

Expression System: HEK293

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

TMPJ-00607

Species: Mouse

Expression System: Human Cells

CD83 Protein, Human, Recombinant (hFc)

TMPJ-01070

Species: Human

Expression System: Human Cells

Cytoglobin/CYGB Protein, Human, Recombinant (His)

TMPJ-01248

Species: Human

Expression System: E. coli

Cytoglobin Protein, Rat, Recombinant (His & Myc)

TMPH-03275

Species: Rat

Expression System: E. coli

B7-2 Protein, Human, Recombinant (His)

TMPJ-00556

Species: Human

Expression System: Human Cells

LAG-3 Protein, Mouse, Recombinant

TMPY-05746

Species: Mouse

Expression System: HEK293

LAG-3 Protein, Mouse, Recombinant (His)

TMPY-04612

Species: Mouse

Expression System: HEK293

14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)

TMPY-02378

Species: Human

Expression System: E. coli

Disintegrin batroxostatin Protein, Bothrops atrox, Recombinant (His & Myc)

TMPH-00213

Species: Bothrops atrox

Expression System: E. coli

B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated

TMPJ-00555

Species: Human

Expression System: Human Cells

14-3-3 beta Protein, Cynomolgus, Recombinant

TMPY-02584

Species: Cynomolgus

Expression System: E. coli

SLAMF1 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00223

Species: Human

Expression System: Human Cells

NTAL Protein, Human, Recombinant (His)

TMPJ-01323

Species: Human

Expression System: Human Cells

Sting Protein, Human, Recombinant (Sumo & His)

TMPJ-01206

Species: Human

Expression System: E. coli

14-3-3 eta/YWHAH Protein, Human, Recombinant (GST)

TMPY-02377

Species: Human

Expression System: E. coli

14-3-3 epsilon Protein, Mouse, Recombinant (GST)

TMPY-02179

Species: Mouse

Expression System: E. coli

LAG-3 Protein, Cynomolgus, Recombinant (hFc)

TMPJ-01421

Species: Cynomolgus

Expression System: Human Cells

LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00321

Species: Human

Expression System: Human Cells

SLAM/CD150 Protein, Human, Recombinant (His)

TMPY-01016

Species: Human

Expression System: HEK293

SLAMF1 Protein, Mouse, Recombinant (His)

TMPJ-00226

Species: Mouse

Expression System: Human Cells

B7-H4 Protein, Mouse, Recombinant (hFc)

TMPY-02658

Species: Mouse

Expression System: HEK293

AICDA Protein, Mouse, Recombinant (His & Myc)

TMPH-02908

Species: Mouse

Expression System: E. coli

14-3-3 epsilon Protein, Human, Recombinant

TMPY-01274

Species: Human

Expression System: E. coli

CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)

TMPJ-00421

Species: Human

Expression System: Human Cells

--------- More ---------

Cat No.	Product Name
L1120	AMPK-Targeted Compound Library	80 compounds
	80 well-chosen unique AMPK-targeted small molecules；
L4300	Wnt/Hedgehog/Notch Compound Library	240 compounds
	A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L1400	MAPK Inhibitor Library	367 compounds
	A unique collection of 367 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;
L3500	Histone Modification Compound Library	480 compounds
	A unique collection of 480 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
L1200	Epigenetics Compound Library	960 compounds
	Well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L9840	Anti-Alzheimer's Disease Compound Library	1040 compounds
	A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
L3700	JAK-STAT Compound Library	256 compounds
	A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening;
L8300	Chromatin Modification Compound Library	256 compounds
	A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);
L1300	PI3K-AKT-mTOR Compound Library	425 compounds
	A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L8720	Pyroptosis Compound Library	1077 compounds
	1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;