acid

7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and suppresses the production of endogenous bile acid and the secretion of biliary cholesterol.

Artelinic acid is a water-soluble artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.

Eicosatetraynoic acid (ETYA) activates PPARα and PPARγ chimeras at 10 μM. Eicosatetraynoic acid (ETYA) is a nonspecific inhibitor of cyclooxygenase and lipoxygenase (ID50=8 μM and 4 μM, respectively).

GSK2983559 free acid is an effective and selective inhibitor of receptor-interacting protein 2 (RIP2). GSK2983559 free acid shows excellent activity in blocking many proinflammatory cytokine responses in human inflammatory bowel disease explant samples an

Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma.

Sultosilic acid piperazine salt (A-585) is a novel lipid-lowering compound that can be used to study type IIb familial combined hyperlipidemia.

Lysophosphatidic acid is a bioactive chemical.

α-Hydroxyglutaric Acid is a natural product for research related to life sciences. The catalog number is T36624 and the CAS number is 2889-31-8.This compound is unstable in powder form and other related salt forms are recommended.

(S)-Coriolic acid (13(S)-HODE) is an important intracellular signaling agent generated by the reaction of linoleic acid with plant and mammalian lipoxygenases. It is involved in cell proliferation and differentiation in various biological systems and inhibits the adhesion of tumor cells to the vascular endothelium, while down-regulating IRGpIIb/IIIa receptor expression at around 1 μM. Additionally, (S)-Coriolic acid is a metabolite of 15-lipoxygenase (15-LOX) and often acts as an endogenous ligand to activate PPARγ. It induces mitochondrial dysfunction and airway epithelial damage.

Muramic acid is a prevalent constituent found in the cell walls of Gram-positive bacteria, serving as a distinguishing marker for such bacteria[1].

Muramic acid HCl is part of the peptidoglycan in the cell wall of many Gram-positive bacteria.

Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].

(6Z)-7-Phenyl-7-(3-Pyridinyl)-6-Heptenoic Acid is a derivative of 7-Phenyl-7-(3-Pyridyl) -6-Heptenoic Acid that can be used in biological research.

Temozolomide Acid (TMZA) is a metabolite of temozolomide (TMZ). Temozolomide processes anticancer activity in vitro. Temozolomide (TMZ) is an oral alkylating agent used to treat glioblastoma multiforme (GBM) and astrocytomas.

4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.

AMI-1 free acid is a potent, cell-permeable, and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with inhibitory concentration 50 (IC50) values of 8.8 μM for human PRMT1 and 3.0 μM for yeast-Hmt1p. It achieves its PRMTs inhibitory activity by obstructing peptide-substrate binding [1].

2-Methylsuccinic acid (Pyrotartaric Acid) is a normal metabolite found in human fluids. Increased urinary levels of 2-Methylsuccinic acid (Pyrotartaric Acid) (together with ethylmalonic acid) are the main biochemical measurable features in ethylmalonic encephalopathy, a rare metabolic disorder with an autosomal recessive mode of inheritance that is clinically characterized by neuromotor delay, hyperlactic acidemia, recurrent petechiae, orthostatic acrocyanosis, and chronic diarrhea.

(E)-2-Butenoic acid (Crotonic acid) is fatty acid formed by the action of fatty acid synthases from acetyl-CoA and malonyl-CoA precursors. Crotonic acid is involved in the fatty acid biosynthesis. Crotonic acid is also found in water extracts from carrot seeds (Daucus carota L.).

Usnic Acid sodium is a natual product.

XANTHENE-9-CARBOXYLIC ACID, with CAS No. 82-07-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. XANTHENE-9-CARBOXYLIC ACID provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Oxotridecanedioic Acid is a biodegradable cationic lipid intermediate for formulating active-agent-loaded lipid nanoparticles.

4-acetyl-3-methyl-5-(methylsulfanyl)-2-thiophenecarboxylic acid, with CAS No. 74597-87-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-acetyl-3-methyl-5-(methylsulfanyl)-2-thiophenecarboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-Adamantaneacetic acid, with CAS No. 4942-47-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Adamantaneacetic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs.