urease — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T76107	Urease
	Urease is produced by many types of bacteria and is an effective virulence factor for some pathogenic bacteria. Urease is also central to the metabolism and virulence of Helicobacter pylori, helping it colonize the stoma...
T67827	Urease Inhibitor 07		Others
	Urease Inhibitor 07 is an isosubstituted metalloproteinase inhibitor with potential activity against Mycobacterium tuberculosis strain H37Rv.		Others
T80893	Urease-IN-9
	Urease-IN-9 (Compound 1e), an urease inhibitor with an IC50 of 19.5 μM, effectively impedes the enzyme's activity [1].
T78237	Urease-IN-6
	Urease-IN-6, a potent Urease inhibitor, exhibits an IC50 value of 14.2 μM and is utilized in the research of peptic and gastric ulcers [1].
T79652	Urease-IN-7
	Urease-IN-7 (Compound 5k) acts as a competitive inhibitor of the enzyme urease, exhibiting an IC50 value of 3.33 μM and a K_i of 3.62 μM. This compound has potential applications in the study of peptic and gastric ulcers...
T62465	Urease-IN-1
	Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).
T64121	Urease-IN-2
	Urease-IN-2 is a non-competitive inhibitor of urease (IC50: 0.94 μM, Ki: 1.6 μM) that non-competitively inhibits Jack bean urease (JBU).
T79656	Urease-IN-8
	Urease-IN-8 (Compound 5e) functions as a competitive inhibitor of urease, with an IC50 value of 3.51 μM and a Ki of 3.11 μM. It is applicable for research pertaining to peptic and gastric ulcers [1].
T73046	Urease-IN-4
	Urease-IN-4 is a potent urease inhibitor, demonstrating an IC50 value of 1.64 µM and exhibiting low cytotoxicity. Additionally, it exhibits inhibitory activity against P. vulgaris, with an IC50 value of 15.27 µg/mL.
T73047	Urease-IN-5
	Urease-IN-5, an urease inhibitor, exhibits a potent inhibitory effect with an IC50 of 1.473 µM and demonstrates low cytotoxicity alongside inhibitory activity against P. vulgaris, marked by an IC50 of 17.78 µg/mL.
T3315	Benurestat	EU-2826	Others , Antibacterial
	Benurestat (EU-2826) is a urease inhibitor.		Others , Antibacterial
T77348	Butylboronicacid		Others
	Butylboronicacid is a competitive inhibitor of urease and acts as a monosaccharide complexing reagent.		Others
T4S0578	Guaijaverin	Guajaverin,Quercetin-3-Arabinoside	Others , Antioxidant , Antibacterial
	1. Guaijaverin (Quercetin-3-Arabinoside) is a urease inhibitor. 2. Guaijaverin has antioxidant activity. 3. Guaijaverin has antibacterial activity against Strep. mutans.		Others , Antioxidant , Antibacterial
T11305	Flurofamide		Others
	Flurofamide is an effective bacterial urease inhibitor and has potential in the treatment of infected urinary calculi.		Others
T1592	Acetohydroxamic acid	Methylhydroxamic acid,Acetic acid,Lithostat,AHA,oxime,N-Hydroxyacetamide	MMP , Antibacterial
	Acetohydroxamic acid (N-Hydroxyacetamide) is an antagonist of the bacterial enzyme urease.		MMP , Antibacterial
TN6604	4-Chlorocinnamic acid
	4-Chlorocinnamic acid is a photosensitive compound. 2-Chlorocinnamic acid and 4-chlorocinnamic acid show potent urease inhibitory activities with the respective IC50 values of 0.66 and 1.10 uM.
T36133	3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one)
	3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) is a non-nucleotide inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; Ki = 50 μM).1,2 It also inhibits urease (IC50 = 84.53 μM for the...
TN3465	Atalantoflavone		Antifection
	Atalantoflavone shows urease inhibitory potential. It displays weak cytotoxic activity against the human Caucasian prostate adenocarcinoma cell line PC-3.		Antifection
TN6659	2-Chlorocinnamic acid
	2-Chlorocinnamic acid is a photosensitive compound, it can inhibit tyrosinase activity. 2-Chlorocinnamic acid and 4-chlorocinnamic acid show potent urease inhibitory activities with the respective IC50 values of 0.66 and...
T79450	Enzyme-IN-2
	Enzyme-IN-2 (compound 15) serves as a potent urease inhibitor, exhibiting anti-ureolytic activity with a K i of 2.36 µM and an IC 50 of 0.75 µM [1].