T1247

Clonidine hydrochloride (Catapres) is a centrally active α-adrenergic agonist used predominantly as an antihypertensive agent.

(E,E,E)-2,7-Dimethylocta-2,4,6-Trienedial is an organic chemical compound characterized by a conjugated trienedial structure that is used as a building block in complex organic synthesis, with potential applications in biology and medicine, particularly for its possible antioxidant and antimicrobial properties and its theorized involvement in cancer prevention pathways.

Picloxydine, a heterocyclic biguanide, possesses antiplaque and antibacterial activity.

Picoprazole is a specific H+/K+-ATPase inhibitor (IC50 of 3.1±0.4 μM).

Actiphenol is a glutarimide antibiotic that exhibits both antifungal and antitumor activity, demonstrating higher potency against pathogens such as coxsackievirus B3, influenza virus A, and herpes simplex virus type 2 than synthetic glutarimide derivatives, and Actiphenol production, along with cycloheximide biosynthesis, is controlled by a single gene cluster encoding an acyltransferase-less type I polyketide synthase in Streptomyces species, highlighting its importance in microbial natural product research.

Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.

Pifithrin-α, p-Nitro, Cyclic (PFN-α) is a cell-permeable, active-form inhibitor of p53.

PIM-447 dihydrochloride is an orally available and selective inhibitor of pan-PIM kinase(Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively).

Acetylcholine, a quaternary ammonium neurotransmitter, is used in biochemical research to study signal transduction in central/peripheral nervous systems.

Gummosin is a natural product that can be used as a reference standard. The CAS number of Gummosin is 51819-92-2.

PIM1-IN-1 is a potent and highly selective PIM kinase inhibitor with strong preference for PIM1 and PIM3 over PIM2, effectively inhibiting BAD phosphorylation without detectable effects on FLT3 or hERG binding, and exhibiting antiproliferative and anticancer activity suitable for mechanistic studies of PIM-driven oncogenic signaling.

PIM447 (LGH447) is an oral, selective pan-PIM kinase inhibitor with antitumor and bone-protective effects. It inhibits PIM1, PIM2, and PIM3, induces apoptosis, and decreases the viability, proliferation, and motility of HuH6 and COA67 cells. PIM447 suppresses tumorigenesis in hepatocellular carcinoma and can be used in the study of multiple myeloma.

Pimozide D4 is a deuterium labeled Pimozide.

Corydamine is a useful organic compound for research related to life sciences and the catalog number is T124768.

Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).

Isopeonol (1-(4-hydroxy-2-methoxyphenyl)ethanone) is a useful life science reagent for biochemical experiments and organic synthesis.

Pinacidil monohydrate is a potassium channel activator, antihypertensive drug.

Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.

Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .

Ochratoxin B is produced by a variety of Aspergillus and Penicillium species and is an analog of the mycotoxin Ochratoxin A, which can contaminate agricultural products.