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MCH(human, mouse, rat) TFA

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  • Inhibitors & Agonists
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MCH(human, mouse, rat) TFA
T75846
MCH (human, mouse, rat) TFA is a potent peptide agonist for MCH receptors, exhibiting binding IC50 values of 0.3 nM for MCH1R and 1.5 nM for MCH2R. It is particularly effective against MCH-2R in a CHO cell line, with functional activation EC50 values of 3.9 nM for MCH-1R and 0.1 nM for MCH-2R, as evidenced by intracellular calcium mobilization measured with FLIPR [1].
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