2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22879 | JNJ 10191584 maleate | JNJ 10191584 maleate salt,VUF6002 maleate | Histamine Receptor |
JNJ 10191584 maleate (VUF6002 maleate) is an orally active and selective antagonist of H4 receptor (Ki = 26 nM). JNJ 10191584 maleate inhibits chemotaxis of eosinophils and mast cells (IC50 = 530 nM and 138 nM). | |||
T27658 | JNJ-10191584 | VUF-6002,JNJ10191584 | Others |
JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammation. |