il-31 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T76724	Nemolizumab	CIM331	Interleukin
	Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of interleukin-31 (IL-31) to its receptor. Nemolizumab can be u...		Interleukin
T76956	Vixarelimab	RG-6536,RO-7622888,KPL-716	Interleukin
	Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody with affinity for the beta chain of the OSM receptor and inhibition of IL-31 and OSM signaling.Vixarelimab can be used to study severe nodular ...		Interleukin
T36648	Tucatinib hemiethanolate
	Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-f...
T76816	Lokivetmab
	Lokivetmab, an Anti-Canine IL31 Recombinant Antibody, is a monoclonal antibody targeting canine IL-31, utilized in research related to atopic dermatitis (AD) in dogs [1].
T35452	β-Defensin-3 (human) (trifluoroacetate salt)
	β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and ...
T35836	PMX-205 (trifluoroacetate salt)
	PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50= 31 nM).1It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma.2,3...
T35453	β-Defensin-4 (human) (trifluoroacetate salt)
	β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at...
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cari...

Compounds

Nemolizumab

T76724

Synonym: RG-6536,RO-7622888,KPL-716

Target: Interleukin

Tucatinib hemiethanolate

β-Defensin-3 (human) (trifluoroacetate salt)

T35452

Synonym:

Target:

PMX-205 (trifluoroacetate salt)

T35836

Synonym:

Target:

β-Defensin-4 (human) (trifluoroacetate salt)

T35453

Synonym:

Target:

β-Defensin-2 (human) (trifluoroacetate salt)

T35451

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04107	IL-31 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-31 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q6EBC2.
TMPJ-00047	IL-31 Protein, Human, Recombinant	Human	E. coli
	Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. Human IL-31 cDNA encodes...
TMPY-01940	IL-31 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-31 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number is Q6EAL8.
TMPY-05523	IL-31 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IL-31 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.8 kDa and the accession number is A0A8J8XFW3.
TMPY-03802	IL-17F Protein, Human, Recombinant (aa 31-163)	Human	E. coli
	IL-17F Protein, Human, Recombinant (aa 31-163) is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is AAH70124.1.
TMPY-00093	IL-31RA Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-31RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 83.5 kDa and the accession number is EAW54932.1.
TMPY-04236	IL-31RA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-31RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.2 kDa and the accession number is EAW54932.1.
TMPY-01898	IL-17F Protein, Human, Recombinant (aa 31-163, His)	Human	HEK293 Cells
	IL-17F Protein, Human, Recombinant (aa 31-163, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q96PD4.
TMPY-05741	IL-15RA Protein, Human, Recombinant (aa 31-205, hFc)	Human	HEK293 Cells
	IL-15RA Protein, Human, Recombinant (aa 31-205, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.22 kDa and the accession number is Q13261-1.
TMPY-00470	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1.
TMPK-01096	IL-31RA Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex f...
TMPK-01113	IL-31RA Protein, Human, Recombinant (aa 20-519, hFc)	Human	HEK293 Cells
	Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex f...
TMPK-01114	IL-31RA Protein, Human, Recombinant (aa 20-519, His)	Human	HEK293 Cells
	Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex f...
TMPH-02740	IL-31R alpha Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation ch...