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Search Results for " gdc0941 "

3

Compounds

Cat No. Product Name Synonyms Targets
T1994 Pictilisib RG7321,GDC-0941 Apoptosis , PI3K , Autophagy
Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).
T11381 Pictilisib dimethanesulfonate GDC-0941 dimethanesulfonate,GDC-0941 2 MeSO3H salt Apoptosis , DNA-PK , PI3K , mTOR , Autophagy
Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold).
T13847 PROTAC SGK3 degrader-1 SGK3-PROTAC1 SGK
PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of can...
TargetMol