dolastatin-10 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1180	Dolastatin 10	NSC 376128,DLS 10	Microtubule Associated
	Dolastatin 10 (DLS 10) is a powerful peptide with antimitotic properties, effectively inhibiting tubulin polymerization.		Microtubule Associated
T22631	Dolastatin 10 trifluoroacetate		Others
	Dolastatin 10 trifluoroacetate is a potent antimitotic polypeptide isolated from a marine animal and is developed as a potential antitumor agent. Dolastatin 10 is found to have an activity to inhibit tubulin polymerizati...		Others
T4677	MMAD	Monomethylauristatin D,Demethyldolastatin 10,Monomethyl Dolastatin 10	Microtubule Associated
	MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).		Microtubule Associated
T18869	Vat-Cit-PAB-Monomethyl Dolastatin 10		Others
	Vat-Cit-PAB-Monomethyl Dolastatin 10 is an ADC linker-conjugated drug designed to deliver potent antitumor activity. It achieves this through Monomethyl Dolastatin 10, a potent tubulin inhibitor, connected via the Vat-Ci...		Others
T10947	D8-MMAD	Monomethylauristatin D D8,Demethyldolastatin 10 D8,Monomethyl Dolastatin 10 D8	Others
	D8-MMAD is a deuterated form of MMAD, which is a microtubule destroyer.		Others
T18315	MC-Sq-Cit-PAB-Dolastatin10		Others
	MC-Sq-Cit-PAB-Dolastatin10 is a potent antitumor drug-linker conjugate for Antibody-Drug Conjugates (ADC), utilizing Dolastatin10 (a tubulin polymerization inhibitor) connected through the MC-Sq-Cit-PAB ADC linker.		Others
T14350	Soblidotin	Auristatin PE,TZT-1027	Microtubule Associated
	Soblidotin (TZT-1027) (Auristatin PE) is an inhibitor of tubulin polymerization. It is also a novel synthetic Dolastatin 10 derivative.		Microtubule Associated
T9714	Atpenin A5		Potassium Channel
	Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].		Potassium Channel
T34758	Symplostatin 1	Symplostatin-1
	Symplostatin 1 is a dolastatin 10 analog from the marine cyanobacterium Symploca hydnoides.
T15158	Dolastatin 15	DLS 15	Others
	Dolastatin 15, a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the anti-tubulin agent Dolastatin 10. Dolastatin 15 can be used as an ADC cytotoxin and it induces c...		Others
T74148	Dolastatinol
	Dolastatinol, a synthetic analog of Dolastatin 10, serves as a potent low-nanomolar inhibitor of tubulin polymerization.
T74349	AGD-0182
	AGD-0182, a synthetic analogue of the natural tubulin-binding molecule Dolastatin 10 [1], acts as a microtubule disrupting agent.
T16490	PF-06380101	Auristatin-0101,Aur0101	Others
	PF-06380101 is an auristatin microtubule inhibitor and is a cytotoxic Dolastatin 10 analogue. When compared to other synthetic auristatin analogues that are used in the preparation of ADCs, PF-06380101 displays excellent...		Others
T12141	N-Boc-Val-Dil-Dap-Doe		Others
	N-Boc-Val-Dil-Dap-Doe is used to synthesize Dolastatin 10 , which is a potent antimitotic peptide, inhibits tubulin polymerization.		Others
T39576	DBCO-PEG4-VC-PAB-MMAE	DBCO-PEG4-VC-PAB-MMAE
	DBCO-PEG4-VC-PAB-MMAE, an ADC linker comprising DBCO-PEG4-VC-PAB coupled with the tubulin polymerization inhibitor MMAE, serves as a key component in the formulation of antibody-drug conjugates (ADCs). MMAE, a synthetic ...