2-thiouracil

2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent.

5-(2-Hydroxyethyl)-2-thiouracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.

Nucleoside Derivatives - Xylo-nucleosides, Thio-nucleosides

Heterocyclic Compounds - Pyrimidine; Intermediate and Building Blocks - Nucleophile; Nucleoside base;Intermediate and Building Blocks----- Electrophiles

Intermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocyclic Compounds - Pyrimidine; Scaffolds and Templates

6-Phenyl-2-thiouracil ,with CAS No. 36822-11-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Phenyl-2-thiouracil provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Carboxy-2-thiouracil is a compound with antitumor activity that forms complexes with metal ions, exhibiting significant biological effects.

5,6-dimethyl-2-Thiouracil is a heterocyclic building block that has been used in the synthesis of anti-HIV-1 pyrimidinones.1 It has also been used as an internal standard for the quantification of thyreostats, including 2-thiouracil, in bovine plasma.2 |1. Navrotskii, M.B. Synthesis and anti-HIV-1 activity of new 2-[(2-phthalimidoethyl)thio]-4(3H)-pyrimidinone derivatives. Pharm. Chem. J. 39(9), 466-467 (2005).|2. Schmidt, K.S. In-house validation and factorial effect analysis of a liquid chromatography-tandem mass spectrometry method for the determination of thyreostats in bovine blood plasma. Anal. Bioanal. Chem. 406(3), 735-743 (2014).

2-Thiouracil (Standard) is the standard substance of 2-Thiouracil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 2-Thiouracil (Deracil) is a thiolated uracil derivative that is a known anti-hyperthyroid agent.

5,6-dimethyl-2-Thiouracil (Standard) is the standard substance of 5,6-dimethyl-2-Thiouracil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 5,6-dimethyl-2-Thiouracil is a heterocyclic building block that has been used in the synthesis of anti-HIV-1 pyrimidinones.1 It has also been used as an internal standard for the quantification of thyreostats, including 2-thiouracil, in bovine plasma.2

6-Phenyl-2-thiouracil (Standard) is the standard substance of 6-Phenyl-2-thiouracil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments.

Heterocyclic compound - pyrimidine; building block - nucleobase

Heterocyclic Compounds - Pyrimidine; Intermediate and Building Blocks - Nucleoside base

Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.

Benzylthiouracil (6-Benzyl-2-thiouracil) induces ANCA-associated glomerulonephritis in Graves' disease patients and is used to study hyperthyroidism.

Methylthiouracil (Standard) is the standard substance of Methylthiouracil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Methylthiouracil is a thiourea-class antithyroid agent that inhibits the synthesis of thyroid hormones and is commonly used to treat hyperthyroidism. Studies have shown that Methylthiouracil can also suppress the production of TNF-α and IL-6, as well as inhibit the activation of NF-κB and ERK1/2. It can be used to induce hyperlipidemia and neurological disorder models.

Propylthiouracil (Standard) is the standard substance of Propylthiouracil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Propylthiouracil (6-n-Propylthiouracil) is a thyroid peroxidase inhibitor and also a 5' -deiodinase inhibitor.

PF-1355 (PF 06281355) is a selective 2-thiouracil mechanism-based MPO inhibitor. PF-1355 is used for treatment of vasculitic diseases.