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Home > Metabolism > PDE > Diprophylline
Catalog No. T0892    CAS 479-18-5
Pack Size
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1 mL * 10 mM (in DMSO)
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Documents and Quality Management
Purity:99.10% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Dyphylline?is a?xanthine?derivative.?Dyphilline?exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties.?Dyphilline?probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular?cAMP. This results in relaxation of bronchial smooth muscle and other smooth muscles.?Dyphylline?may also antagonize?adenosinereceptors.?Dyphylline?is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.

Research Area:
Respiratory system
Chemical Information:
Molecular Weight 254.25
Formula C10H14N4O4
CAS Number 479-18-5
Solubility DMSO:48 mg/mL (188.8 mM);Water:47 mg/mL (184.9 mM);Ethanol:<1 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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