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c-Kit
Cat.No. Product Name Information Area
T4332 c-Kit-IN-1 DCC-2618 is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM). Others
T3452 ISCK03 ISCK03 is a selective SCF/c-Kit inhibitor. Immunology
T6930 Pazopanib HCl Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEG... Others
T2288 Motesanib Motesanib is an orally bioavailable receptor tyrosine kinase inhibitor with potential... Cancer
T3072 XL019 XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectiv... Cancer
T2624 OSI 930 OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth fact... Cancer
T2620 G-749 G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the ... Cardiovascular System
T2609 Masitinib Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in... Cancer
T2582 Apatinib Apatinib is an orally bioavailable and specific VEGFR2 inhibitor (IC50: 1 nM). In add... Cancer
T2516 Amuvatinib Amuvatinib is an orally bioavailable synthetic carbothioamide with potential antineop... Cancer
T2500 Cediranib Cediranib (AZD2171) is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of... Cancer
T2446 KI8751 KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM. Cancer
T2115 Pexidartinib Pexidartinib is a capsule formulation containing a small-molecule receptor tyrosine k... Cancer
T2070 CEP-32496 CEP-32496 is a highly potent inhibitor of BRAF. Other
T1925 PLX647 PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM). Cancer
T1830 BX795 BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity ... Other
T1667 Tandutinib Tandutinib (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also ... Cancer
T1621 Imatinib Mesylate Imatinib mesylate is a tyrosine kinase receptor inhibitor with antineoplastic activit... Cancer
T1452 Axitinib Axitinib is an orally bioavailable tyrosine kinase inhibitor with IC50s of 0.1, 0.2, ...
T1448 Dasatinibhot Dasatinib is a potent inhibitor of the Bcr-Abl and Src family (IC50s: 0.6, 0.8, 79 an... Cancer
T0374L Sunitinib Sunitinib, a multi-targeted RTK inhibitor, is targeting PDGFRβ and VEGFR2 (Flk-1) wit... Cancer
T0374 Sunitinib Malate Sunitinib is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine ki... Cancer
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