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Home > Hedgehog-Smoothened
Cat.No. Product Name Information Area
T3588 JK184 JK184 is a potent Hedgehog (Hh) pathway inhibitor. Others
T3156 Ciliobrevin A Ciliobrevin A is a?hedgehog?(Hh) signaling pathway inhibitor with IC50 less than 10 μ...
T6891 MK-4101 MK-4101, an effective inhibitor of the Hedgehog pathway, has anti-tumor activity thro... Others
T3363 Jervinenew The biological activity of Jervine is mediated via its interaction with the 7 passes... Others
T6514 Glasdegib Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibit... Cancer
T3070 GANT61 GANT 61 is an inhibitor for Gli1 and Gli2. Cancer
T2825 Cyclopamine Cyclopamine, a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs ...
T2666 Taladegib Taladegib is an orally bioavailable small molecule antagonist of the Hedgehog (Hh)-li... Cancer
T2590 Vismodegib Vismodegib is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50:... Cancer
T2450 SANT-1 SANT-1 directly binds to Smoothened (Smo) receptor (Kd: 1.2 nM) and inhibits Smo agon... Other
T2299 BMS-833923 BMS-833923, an orally bioavailable Smoothened antagonist, inhibits BODIPY cyclopamine... Cancer
T1926 Sonidegib LDE225 (NVP-LDE225; Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (H... Other
T1810 Purmorphamine Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopami... Other
T1779 Smoothened Agonist SAG is a potent Smo receptor agonist and activates the Hedgehog signaling pathway. Other