BODIPY 581/591 C11 is a fluorescent radioactive probe used to indicate lipid peroxidation and antioxidant efficacy in model membrane systems and living cells.
LysoTracker Red (LysoTracker Red DND-99) is a fluorescent probe compound for lysosomal capture, a transport substrate for P-glycoprotein, with a maximum excitation/emission wavelength of 577/590 nm.LysoTracker Red can be used for the long-term tracking of acidic vesicles.
5-ROX (5-Carboxy-X-rhodamine), a rhodamine dye, exhibits strong fluorescence in aqueous buffer with an excitation wavelength (λexit) of 580 nm (ε = 3.6×10^4/(M·cm)) and an emission wavelength (λemit) of 604 nm (ϕ = 0.94).
5(6)-ROX (5(6)-Carboxy-X-rhodamine) is a nucleic acid fluorescent label and rhodamine dye with Ex/Em=570/595 nm. It serves as a correction dye for real-time quantitative PCR and is widely applied in DNA sequencing and fluorescent labelling.
BODIPY-581/591 NHS ester, a vivid red fluorescent dye (excitation: 581 nm; emission: 591 nm), is noted for its hydrophobic qualities ideal for labeling lipids, membranes, and other lipophilic substances [1].
BDP 581/591 amine hydrochloride, a BODIPY dye linker, is a universal, photostable fluorophore. The amine group addition enables the compound to react with carboxylic acids, activated NHS esters, and other carbonyl groups [1].
Cyamine3.5 NHS ester is a squaraine dye utilized in the development of fluorescent probes and biological labeling, characterized by its intermediate wavelength fluorescence emission properties. Specially designed for reactions with amino groups to form stable covalent bonds, it is ideal for labeling biomolecules. Ex/Em(nm)=591/604.
Flutax-2 (5/6-mixture), an active fluorescent derivative of paclitaxel, binds to polymerized α,β tubulin dimers, with an excitation/emission wavelength of 496/524 nm. Derived from paclitaxel, a diterpenoid secondary metabolite from Taxus species utilized in various cancer research [1], it requires storage protection from light.
BDP 581/591 maleimide, a linker of the BDP 581/591 dye, has a long fluorescence lifetime and is used for fluorescence polarization assays. The maleimide group reacts with thiol groups to form thioester bonds between pH 6.5 and 7.5, enabling the labeling of sulfhydryl groups of proteins and peptides.
5(6)-Carboxynaphthofluorescein diacetate serves as a fluorescent substrate in esterase assays, where it is cleaved by intracellular esterases, resulting in red fluorescence for enzyme activity measurement (Ex = 590 nm; Em = 645 nm) [1].
BDP 581/591 NHS ester, a borondipyrromethene dye (Ex=585 nm, Em=594 nm), exhibits a relatively long fluorescence lifetime and significant two-photon excitation cross-section. This compound is applicable in fluorescence polarization analysis, interacts with reactive oxygen species (ROS) to modify fluorescence, and, as an NHS ester derivative, binds to the primary and secondary amine groups of proteins, peptides, and various molecules. Storage instructions highlight the importance of protecting it from light.
AF 594 azide (triethylamine) is the azide derivative of the red fluorescent dye AF 594, characterized by a high fluorescence quantum yield and remarkable photostability (maximum excitation wavelength at 594 nm, maximum emission wavelength at 615 nm). It reacts with alkynyl derivatives (terminal alkynes and cyclooctynes) through the azide group to form stable adducts.
TFAX 594,SE is a red fluorescent dye that maintains its fluorescence properties across a pH range of 4 to 10. It produces highly intense and photostable conjugates when bound to proteins or antibodies, such as [goat anti-mouse IgG].
BDP 581/591 alkyne, a moderately hydrophobic borondipyrromethene fluorophore, is designed for specialized applications requiring specific fluorescent properties.
ER-Tracker dye is a derivative of BODIPY conjugated with Glibenclamide, displaying high selectivity for the endoplasmic reticulum. At low concentrations, it remains non-toxic to cells and serves as an environmentally sensitive probe that retains some fluorescence after formaldehyde treatment. It is characterized by its high fluorescence lifetime and strong extinction coefficient. Glibenclamide acts as an ATP-dependent K+ channel blocker (Kir6, KATP) and a CFTR Cl- channel blocker, binding within the endoplasmic reticulum. ER-Tracker is not suitable for staining fixed cells. Ex/Em = 587/615 nm.
BDP 581/591 carboxylic acid, a highly photostable fluorescent dye (Ex=585 nm, Em=594 nm), possesses a free carboxylic acid group. This group can undergo catalysis by agents (such as EDC or HATU) to form stable amide bonds with primary amines. The compound is also utilized for ROS detection.
BDP 581/591 azide, an azide derivative of the universal, photostable fluorophore BDP 581/591, can be used for conjugation with small molecules and biomolecules to construct tracers for fluorescence polarization assays and microscopy probes [1].