1. Fargesin ((+ -)-Fargesin) as a potential β1AR antagonist through cAMP PKA pathway could protect against myocardial ischemia reperfusion injury in rats. 2. Fargesin improves dyslipidemia and hyperglycemia by activating Akt and AMPK in WAT.
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protect against neuronal death from 1-met
1,2-O-Dilinoleoyl-3-O-Beta-D-Galactopyranosylracglycerol is a natural product used in life sciences research. The catalog number is T2A2400, and the CAS number is [111187-15-6].
Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the mini
(-)-Fargesol is a nartural product from the flowers buds of Magnolia fargesii,the dried flower buds of M. fargesii, has been used as therapy for nasal empyema and headache.
Maglifloenone is a natural product of Magnolia, Magnoliaceae. The catalog number is TN5409 and the CAS number is 82427-77-8. Maglifloenone can be used as a reference standard.
Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.
Magnolignan A-2-O-beta-D-glucopyranoside has medium cytotoxic activity against HEp-2 and HepG2 cells, with IC(50) of 13.3 microM, and 46.4 microM, respectively.
(1S,2S)-threo-Honokitriol is a natural product of Magnolia, Magnoliaceae. The catalog number is TN6655 and the CAS number is 1099687-80-5. (1S,2S)-threo-Honokitriol can be used as a reference standard.
Fargesone A shows inhibitory effects on nitric oxide (NO) production in the lipopolysaccharide plus interferon-gamma activated-murine macrophage cell line, J774.1.
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear translocation of p65 subunit of NF-kappaB. It also exhibits antiallergic effects without affecting the viability of bone marrow-derived mast cells.