Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macroph

Protostemotinine is a natural product from Stemona japonica.

Delta-Tocopherol, an isomer of Vitamin E, possesses antioxidant activity and may serve as an effective ingredient in whitening cosmetics with reduced skin toxicity.

1. Tuberostemonine (Tuberstemonine) exhibits relatively higher intestinal permeabilities. 2. Tuberostemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction.

(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) is a potential inhibitor of the mitogen-activated phosphor kinase pathway and an anti-inflammatory agent first isolated from the medicinal plant S. tuberosa. Additionally, it shows promising anthelmintic activity against Haemonchus contortus.

Bisdehydroneotuberostemonine shows significant inhibitory effect on lipopolysaccharide-induced nitric oxide production in BV2 microglia at 100 uM.

Dehydro-δ-tocopherol shows antioxidant capacities.

Stilbostemins N may exhibit moderate antibacterial activities.

Neostenine shows significant antitussive activity.

Stilbostemin A, stilbostemin B , stilbostemin D , stilbostemin F , and stilbostemin G show structure-dependent inhibition of leukotriene biosynthesis with IC(50) values ranging from 3.7 to >50 microM.

Sessilifoline A is a natural product from Stemona japonica.

1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro

Neotuberostemonone is a natural product from Stemona mairei.