Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macroph

Protostemotinine is a natural product from Stemona japonica.

1. Tuberostemonine (Tuberstemonine) exhibits relatively higher intestinal permeabilities. 2. Tuberostemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction.

Delta-Tocopherol, an isomer of Vitamin E, possesses antioxidant activity and may serve as an effective ingredient in whitening cosmetics with reduced skin toxicity.

(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) is a potential inhibitor of the mitogen-activated phosphor kinase pathway and an anti-inflammatory agent first isolated from the medicinal plant S. tuberosa. Additionally, it shows promising anthelmintic activity against Haemonchus contortus.

Bisdehydroneotuberostemonine shows significant inhibitory effect on lipopolysaccharide-induced nitric oxide production in BV2 microglia at 100 uM.

Dehydro-δ-tocopherol shows antioxidant capacities.

Stilbostemins N may exhibit moderate antibacterial activities.

Neostenine shows significant antitussive activity.

Stilbostemin A, stilbostemin B , stilbostemin D , stilbostemin F , and stilbostemin G show structure-dependent inhibition of leukotriene biosynthesis with IC(50) values ranging from 3.7 to >50 microM.

Sessilifoline A is a natural product from Stemona japonica.

1. Protostemonine has anti-inflammatory activity, it effectively attenuates LPS-induced inflammatory responses in vitro and in vivo; the beneficial effects are associated with the decreased phosphorylation of MAPK and AKT and the reduced expression of pro

Neotuberostemonone is a natural product from Stemona mairei.