T1985 |
WHI-P154
|
211555-04-3
|
99.19%
|
|
WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.
|
T6077 |
ZM-447439
|
331771-20-1
|
99.11%
|
|
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective f...
|
T2709 |
TAK-901
|
934541-31-8
|
99.1%
|
|
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others....
|
T6315 |
MLN8054
|
869363-13-3
|
99.05%
|
|
MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.
|
T0152 |
Bosutinib
|
380843-75-4
|
99%
|
|
Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.
|
T6732 |
WYE-687
|
1062161-90-3
|
98.98%
|
|
WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(...
|
T23176 |
PP 3
|
5334-30-5
|
98.92%
|
|
PP 3 is a Negative control for the Src kinase inhibitor PP 2
|
T78605 |
CpCDPK1/TgCDPK1-IN-1
|
1092788-23-2
|
98.71%
|
|
CpCDPK1/TgCDPK1-IN-1 is a potent dual inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infectio...
|
T37603L |
Osteogenic Growth Peptide (10-14) acetate
|
|
98.69%
|
|
Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesi...
|
T9411 |
KX2-361
|
897016-26-1
|
98.52%
|
|
KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma
|
T23128 |
PD180970
|
287204-45-9
|
98.47%
|
|
PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit. PD180970 can be used in studies...
|
T6594 |
MNS
|
1485-00-3
|
98.45%
|
|
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
|
T2327 |
Pelitinib
|
257933-82-7
|
98.37%
|
|
Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).
|
T6350 |
CHIR-124
|
405168-58-3
|
98.35%
|
|
CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.
|
T22552L |
AD57
|
1093380-42-7
|
98.23%
|
|
AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.
|
T30855 |
CGP77675
|
234772-64-6
|
98.23%
|
|
CGP77675 (ZINC1488120) is a potent and selective inhibitor of Src family kinase with IC50s of 5-20 and 40 nM for the phosphorylation of peptide substrates and au...
|
T12906 |
SI-2 hydrochloride
|
1992052-49-9
|
98.18%
|
|
SI-2 hydrochloride (EPH 116 hydrochloride) is a highly promising inhibitor of SRC-3 SMI: SRC-3 (PPI)(IC50 values of 3-20 nM for breast cancer cell death), with a...
|
TN1440 |
Beta-Hydroxyisovalerylshikonin
|
7415-78-3
|
98.16%
|
|
Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor ...
|
T2642 |
PD173074
|
219580-11-7
|
98.15%
|
|
PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for ...
|
T9650 |
AZ12672857
|
945396-55-4
|
98.05%
|
|
AZ12672857 is an inhibitor of EphB4 with IC50 of 1.3 nM. AZ12672857 inhibits cell proliferation of Src transfected 3T3 cells with IC50 of 2 nM and autophosphoryl...
|