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MELK

Maternal embryonic leucine zipper kinase (MELK) is an enzyme that in humans is encoded by the MELK gene. MELK is a serine/threonine kinase belonging to the family of AMPK/Snf1 protein kinases. MELK was first identified present as maternal mRNA in mouse embryos. MELK expression is elevated in a number of cancers and is an active research target for pharmacological inhibition.
Cat. No. Product name CAS No. Purity Chemical Structure
T35342 MELK-8a Dihydrochloride 98%
T11732 JTV-519 hemifumarate 1435938-25-2 98%
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a p...
T24152 HTH-01-091 2000209-42-5 98%
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK...
T12237 NMS-P715 1202055-32-0 98%
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
T11997 MELK-IN-1 2095596-44-2 98%
MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).
T1759 OTSSP167 1431697-89-0 98%
MELK Inhibitor OTS167 is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.
T11996 MELK-8a hydrochloride 2096992-20-8 98%
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). 
T21559 OTSSP167 hydrochloride 1431698-10-0 98%
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).
MELK-8a Dihydrochloride
T35342
JTV-519 hemifumarate
T11732
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a p...
HTH-01-091
T24152
HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3, smMLCK...
NMS-P715
T12237
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
MELK-IN-1
T11997
MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).
OTSSP167
T1759
MELK Inhibitor OTS167 is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity.
MELK-8a hydrochloride
T11996
MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). 
OTSSP167 hydrochloride
T21559
OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM).