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Integrase

Retroviral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that integrates—forms covalent links between—its DNA (genetic information) into that of the host cell it infects.[citation needed] Retroviral INs are not to be confused with phage integrases (recombinases), such as λ phage integrase, as discussed in site-specific recombination.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T6589 MK-2048 869901-69-9 98%
MK-2048
MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
TN4455 Lucialdehyde B 480439-84-7 98%
Lucialdehyde B
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, an...
TN1671 Ganoderone A 873061-79-1 98%
Ganoderone A
Ganoderone A exhibits potent inhibitory activity against herpes simplex virus.
T2239L Raltegravir 518048-05-0 99.05%
Raltegravir
Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV I...
T2239 Raltegravir potassium 871038-72-1
Raltegravir potassium
Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
MK-2048
T6589
MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
Lucialdehyde B
TN4455
Lucialdehyde B exhibits potent inhibitory activity against herpes simplex virus. It shows cytotoxic effects on Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, an...
Ganoderone A
TN1671
Ganoderone A exhibits potent inhibitory activity against herpes simplex virus.
Raltegravir
T2239L
Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV I...
Raltegravir potassium
T2239
Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
TargetMol