Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T4379 | Tropifexor | 1383816-29-2 | 99.3% |
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Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM. | ||||
T8895 | Altenusin | 31186-12-6 | 98.97% |
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Altenusin is a natural nonsteroidal fungal metabolite, as a novel selective agonist of FXR with an EC50 value of 3.2 ± 0.2 μM. | ||||
T29078 | Ursodeoxycholic acid sodium | 2898-95-5 | 98.55% |
|
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeox... | ||||
T27460 | GSK2324 | 1020567-30-9 | 98.50% |
|
GSK2324 is a potent FXR agonist for the treatment of NAFLD by controlling hepatic lipids through reduced uptake and selective reduction of fatty acid synthesis. | ||||
T5574 | Guggulsterone | 95975-55-6 | 98% |
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Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen. | ||||
T7436 | Cilofexor | 1418274-28-8 | 98% |
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Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist. | ||||
T2968 | Hyodeoxycholic acid | 83-49-8 | 97.26% |
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Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia. | ||||
T8471 | Vonafexor | 1192171-69-9 | 100% |
|
Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects | ||||
T6053 | Turofexorate Isopropyl | 629664-81-9 |
|
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Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM | ||||
T11661 | INT-767 | 1000403-03-1 | 98% |
|
INT-767 is a potent farnesoid X receptor (FXR)/TGR5 dual agonist that prevents NASH and promotes visceral adipose brown lipogenesis and mitochondrial function fo... | ||||
T77124 | Osocimab | 2056878-75-0 | 98% |
Osocimab
|
Osocimab (BAY 1213790) is a potent anti-FXIa antibody with a Ki value of 2.4 nM and an EC50 value of 0.2 nM.Osocimab may reduce thrombosis through FXI inhibition... | ||||
T6344 | Sevelamer hydrochloride | 152751-57-0 | 98% |
|
Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.... |