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EBI2/GPR183

G-protein coupled receptor 183 also known as Epstein-Barr virus-induced G-protein coupled receptor 2 (EBI2) is a protein that in humans is encoded by the GPR183 gene.[5] This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of the Burkitt's lymphoma cell line BL41.[6] This gene is predicted to encode a G protein-coupled receptor that is most closely related to the thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not in T-lymphocyte cell lines or peripheral blood T lymphocytes.[5]

  • ML401
    T82341597489-14-9
    ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
    • $135
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    TargetMol | Inhibitor Sale
  • NIBR189
    T71561599432-08-2
    NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively)
    • $30
    In Stock
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  • 7α,25-Dihydroxycholesterol
    T1406364907-22-8
    7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][
    • $175
    35 days
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