Search Result

Search Results for " annexin-a "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1212	N-Boc-Phe-Leu-Phe-Leu-Phe	Boc-FLFLF	Others
	N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin. Boc-Phe-Leu-Phe-Leu-Phe is used extensive...		Others
T9566	PY-60		Annexin A , YAP
	PY-60 potently activates YAP transcriptional activities targeting annexin A2 (Kd = 1.4 µM). PY-60 activates a proproliferative, YAP-dependent transcriptional program in the adult animal capable of remodeling the epidermi...		Annexin A , YAP
T36432	A2ti-1		Virus Protease
	A2ti-1 is a highly selective inhibitor of annexin A2/S100A10 heterotetramer (A2t) (IC50: 24 μM) that inhibits ARV-mediated activation of Src and p38 mitogen-activated protein kinase (MAPK). A2ti-1 can be used to study hu...		Virus Protease
T40614	LCKLSL
	LCKLSL, an N-terminal hexapeptide, acts as a competitive inhibitor of annexin A2 (AnxA2), effectively preventing the binding of tissue plasminogen activator (tPA) to AnxA2 while also inhibiting the generation of plasmin....
TP2083	Ac9-25
	N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. Acts as a formyl peptide receptor 1 (FPR1) ligand and stimulates neutrophil NADPH oxidase activation.
T39855	LysoTracker Red	LysoTracker Red DND-99
	LysoTracker Red (LysoTracker Red DND-99) is a paraformaldehyde fixable probe that concentrates into acidic compartments of cells and tissues. LysoTracker Red is an indicator of cell death in a manner similar to other st...
TP2482	LCKLSL acetate	LCKLSL acetate(533902-29-3 free base)	Annexin A
	LCKLSL acetate is a competitive annexin A2 (AnxA2) inhibitor. LCKLSL acetate potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2 and the generation of plasmin. LCKLSL acetate has anti-angiogenic ...		Annexin A
T75813	Ac9-25 TFA
	Ac9-25 TFA, an N-terminal peptide of Annexin I, functions as a formyl peptide receptor (FPR) agonist, activating neutrophil NADPH oxidase via FPR [1] [2].
T83727	Tat-NTS Peptide TFA	Tat-Nuclear Translocation Signal Peptide
	Tat-NTS peptide, a cell-penetrating compound, comprises the HIV-1 Tat protein transduction domain fused with a 10-amino acid sequence (residues 228-237) from the repeat III domain of annexin A1, serving as a nuclear tran...
T83667	A11 TFA	CPP-EYVQTVKSSKG
	A11, a cell-penetrating peptide, integrates the HIV-1 Tat protein transduction domain with an 11-amino acid segment from the annexin A1 N-terminus (residues 20-30). This compound disrupts the interaction between annexin ...
T70741	AZ-TAK1
	AZ-Tak1 is a potent and a relatively selective inhibitor of TAK1 kinase activity, with an IC50 of 0.009 mM. AZ-Tak1 treatment decreased the level of p38 and ERK in mantle cell lymphoma cells, and induced apoptosis in a d...
T71287	CDKI-83
	CDKI-83 is a potent CDK9 inhibitor. The compound shows effective anti-proliferative activity in human tumour cell lines with GI50 <1 μM, and is capable of inducing apoptosis in A2780 human ovarian cancer cells as determi...
T70962	MHY219
	MHY219 is a novel HDAC inhibitor. MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells. MHY219 was shown to enhance the cytotoxicity on DU145 cells (IC50, 0.36 μM) whe...
T36978	AS-99 TFA
	AS-99 TFA is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 TFA blocks cell proliferation, induces apoptosis and different...
T36977	AS-99 free base
	AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity. AS-99 blocks cell proliferation, induces apoptosis and differentiation, ...

Compounds

N-Boc-Phe-Leu-Phe-Leu-Phe

Target: Annexin A, YAP

A2ti-1

T36432

Synonym:

Target: Virus Protease

Synonym: LysoTracker Red DND-99

Target:

LCKLSL acetate

TP2482

Synonym: LCKLSL acetate(533902-29-3 free base)

Synonym: Tat-Nuclear Translocation Signal Peptide

Target:

A11 TFA

T83667

Synonym: CPP-EYVQTVKSSKG

Cat No.	Product Name	Synonyms	Targets
TN4046	Excisanin A		MMP , FAK , PARP , GSK-3 , NF-κB , Wnt/beta-catenin , Akt , Caspase , PI3K , Prostaglandin Receptor , JNK
	ExcisaninA may be a potent inhibitor of AKT signaling pathway in tumor cells, it can inhibit invasion by suppressing MMP-2 and MMP-9 expression, it may be a potential anti-metastatic chemotherapeutic agent for the treatm...

Natural Products

Excisanin A

TN4046

Synonym:

Target: MMP, FAK, PARP, GSK-3, NF-κB, Wnt/beta-catenin, Akt, Caspase, PI3K, Prostaglandin Receptor, JNK

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00840	ANXA3 Protein, Human, Recombinant	Human	E. coli
	Annexin A3（ANXA3）contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduc...
TMPY-00811	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein	CMV	HEK293
	Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomega...
TMPY-01201	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (His)	CMV	HEK293
	Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomega...
TMPY-00731	Cathepsin B Protein, Human, Recombinant (His)	Human	HEK293
	Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPJ-00888	ANXA7 Protein, Human, Recombinant	Human	E. coli
	Annexin A7 (ANXA7) is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin A7 has a unique, highly hydrophobic N-terminal domain and a conserved C-terminal region. The C-terminal reg...
TMPJ-00766	ANXA1 Protein, Human, Recombinant	Human	E. coli
	Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-infla...
TMPJ-00844	ANXA8 Protein, Human, Recombinant	Human	E. coli
	Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats ...
TMPJ-01381	ANXA10 Protein, Human, Recombinant	Human	E. coli
	Annexin A10 (ANXA10) contains four Annexin repeats and is a member of the Annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in sign...
TMPJ-00590	ANXA13 Protein, Human, Recombinant	Human	E. coli
	Annexin A13 (ANXA13) belongs to the annexin family which plays a role in phospholipase inhibition, cytoskeletal interactions, intracellular signal transduction pathways and regulation of cellular growth. ANXA13 contains ...
TMPJ-00799	ANXA2 Protein, Human, Recombinant	Human	E. coli
	Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression r...
TMPY-02592	Annexin VI/ANXA6 Protein, Human, Recombinant (His)	Human	E. coli
	Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca2+-dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endo...
TMPY-00540	ANXA5 Protein
	The placental anticoagulant protein Annexin A5 (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintai...
TMPY-01926	S100A10 Protein, Human, Recombinant (His)	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that...
TMPY-05759	Annexin V/ANXA5 Protein, Human, Recombinant, Biotinylated	Human	E. coli
	The placental anticoagulant protein Annexin A5 (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintai...
TMPY-02540	Annexin V/ANXA5 Protein, Human, Recombinant	Human	E. coli
	The placental anticoagulant protein Annexin A5 (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintai...
TMPY-00585	Annexin A8 Protein, Human, Recombinant (His)	Human	E. coli
	We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA...
TMPY-00812	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (aa 1-700, hFc)	CMV	HEK293
	Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomega...
TMPY-06816	HSV 2 (strain 333) Glycoprotein B/gB Protein (His)	HSV2	Baculovirus-Insect Cells
	Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomega...
TMPY-00810	Human cytomegalovirus (HCMV) Glycoprotein B/gB Protein (hFc)	CMV	HEK293
	Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomega...
TMPY-02640	FAM3B Protein, Human, Recombinant (hFc)	Human	HEK293
	Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and b...
TMPY-04503	Cathepsin B Protein, Rat, Recombinant (His)	Rat	HEK293
	Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...
TMPY-02144	Cathepsin B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This proteas...