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Search Result

Search Results for " acetyl-coa-carboxylase "

Targets

Acetyl-CoA Carboxylase

24

Compounds

6

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T3510 Olumacostat Glasaretil Acetyl-CoA Carboxylase
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.
T7163 PF-05175157 Acetyl-CoA Carboxylase
PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively
TQ0243 ND-646 Acetyl-CoA Carboxylase
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)
T5046 Haloxyfop Haloxyfop Acid,(±)-Haloxyfop Others , Acetyl-CoA Carboxylase
(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.
T3988 TOFA MDL14514,RMI14514 Acetyl-CoA Carboxylase
TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).
T14991 CMS-121 CMS121 Acetyl-CoA Carboxylase
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect...
T1889 CP-640186 CP 640186 Acetyl-CoA Carboxylase
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.
T3622 CP-640186 hydrochloride CP 640186 HCl Acetyl-CoA Carboxylase
CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...
T7184 Firsocostat ND-630,NDI-010976,GS-0976 Acetyl-CoA Carboxylase
Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
T72180 Acetyl-CoA Carboxylase-IN-1
Acetyl-CoA Carboxylase-IN-1 is a potent inhibitor of acetyl-CoA carboxylase (ACC), exhibiting an inhibition concentration (IC50) of less than 5 nM. This compound also displays antibacterial activity.
T9209 PF-05221304 STAT5 Inhibitor III,NSC 170984,R 6238,,Clesacostat Acetyl-CoA Carboxylase
PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.
T73350 BAY-3827 Acyltransferase , AMPK
BAY-3827 is a potent and selective AMPK inhibitor with potential antitumor activity, showing antiproliferative activity in an androgen-dependent prostate cancer model. BAY-3827 inhibits the phosphorylation of acetyl CoA ...
T4309 CIL56 CA3 Ferroptosis , ROS
CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated, monounsaturated, and polyuns...
T70663 ND-654
ND-654 is an acetyl CoA carboxylase inhibitor.
T69277 (±)-Diclofop
(±)-Diclofop is an Acetyl-CoA carboxylase (ACCase) inhibiting herbicide.
T12062 MK-4074 Others
MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).
T36785 Fluazifop-P-butyl
Fluazifop-P-butyl is an arylophenoxypropionate group graminicide that functions as an inhibitor of acetyl-CoA carboxylase (ACCase)[1].
T20135 Diphenamid Trefmid,Enide 50,Enide 50W,Rideon,Fenam,Caswell No. 395
Diphenamid is a chemical compound from the group of acetamides and a herbicide. The effect is based on the inhibition of acetyl-CoA carboxylase.
T61430 S-2E
S-2E is a compound that functions as an orally active, noncompetitive inhibitor of both HMG-CoA reductase and acetyl-CoA carboxylase. It exhibits an anti-hyperlipidemic action, making it suitable for studying conditions ...
T61341 A-908292
A-908292 is a highly potent and selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), displaying an impressive IC50 of 38 nM. This compound serves as a valuable tool in the investigation of fatty acid metabolism [1].
T40675 CP-610431
CP-610431 is a reversible, ATP-uncompetitive inhibitor of acetyl-CoA carboxylase (ACC), exhibiting isozyme nonselectivity. It inhibits both ACC1 and ACC2 with IC50 values of approximately 50 nM. CP-610431 offers potentia...
T38473 Malonyl Coenzyme A lithium
Malonyl Coenzyme A (lithium) is a coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane. Malonyl Coenzyme A (lithium) is f...
T75251 Firsocostat (S enantiomer)
Firsocostat S enantiomer (ND-630 S enantiomer) is the less active S enantiomer of Firsocostat. Firsocostat is an acetyl-CoA carboxylase ( ACC ) inhibitor.
T35874 CC260
CC260, a selective inhibitor for PI5P4Kα and PI5P4Kβ with Kis of 40 nM and 30 nM respectively, exhibits minimal to no inhibition against other protein kinases like Plk1 and RSK2. It is applicable in the research of cell ...

Recombinant Proteins

Species：
Mouse (2)
Saccharomyces cerevisiae (2)
Candida albicans (1)
Candida glabrata (1)
Expression System：
E. coli (5)
Baculovirus (1)
Tag：
N-terminal 10xHis-tagged (4)
N-terminal 6xHis-tagged (2)
Cat No. Product Name Species Expression System
TMPH-00330 Acetyl-CoA carboxylase Protein, Candida albicans, Recombinant (His) Candida albicans E. coli
TMPH-00339 Acetyl-CoA carboxylase Protein, Candida glabrata, Recombinant (His) Candida glabrata E. coli
TMPH-03432 ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) Saccharomyces cerevisiae E. coli
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle...
TMPH-03431 ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) Saccharomyces cerevisiae E. coli
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle...
TMPH-02479 PRKAA1 Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activat...
TMPH-02478 PRKAA1 Protein, Mouse, Recombinant (His) Mouse Baculovirus
Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activat...
Cat No. Product Name
L2510 Lipid Metabolism Compound Library

496 compounds
A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).

Libraries

Lipid Metabolism Compound Library
L2510
Compounds: 496
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