wnk

WNK-IN-7 is a potent and selective WNK1 kinase inhibitor.

WNK-IN-3 is a novel allosteric inhibitor of WNK kinase.

WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)

WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1 2 3 4).

WNK1-IN-1 is a selective WNK1 (With No lysine (K) 1) inhibitor (IC50 = 1.6 μM) that inhibits the phosphorylation of the endogenous substrate OSR1, and can be used to study hypertension and cancer.

WNK-IN-B is an inhibitor of Wnk signalling. WNK-IN-B is a cell-permeable diaminoacridine derivative that targets the CCT domain of SPAK and OSR1 via reversible binding. WNK-IN-B selectively suppress hypotonic shock-induced WNK signaling pathway activation