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(77)
By Target- Sirtuin
- Apoptosis(13)
- Autophagy(8)
- MDM-2/p53(5)
- Dehydrogenase(3)
- Endogenous Metabolite(3)
- HBV(3)
- HDAC(3)
- HSP(3)
- Others(26)
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Results for "
sirt2
" in TargetMol Product Catalog- Inhibitors & Agonists85
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PROTAC Sirt2 Degrader-1
T166672098487-75-1
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC that acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s > 100 μM)[1].
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SirReal1-O-propargyl
PROTAC Sirt2-binding moiety 1
T186411862237-99-7
SirReal1-O-propargyl is a selective Sirtuin 2 inhibitor (IC50=2.4 μM) and PROTAC ligand. Its propargyl group enables click chemistry reactions such as CuAAc.
- $195
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