saccharomyces cerevisiae

Hexokinase, Saccharomyces cerevisiae (EC 2.7.1.1), is a natural hexokinase from brewer's yeast used in studies of glucose metabolism and enzymatic mechanisms.

Esterase, Saccharomyces cerevisiae (EC 3.1.1.1), is a hydrolase enzyme that catalyzes the breakdown of esters into acids and alcohols.

Phosphoglucose isomerase, Saccharomyces cerevisiae (EC 5.3.1.9), is a vital enzyme for the interconversion of D-glucose-6-phosphate and D-fructose-6-phosphate. It facilitates the second step of glycolysis and is involved in glycogen synthesis, being highly conserved in both bacteria and eukaryotes.

Adenosine-5'-triphosphate Sulfurylase, Saccharomyces cerevisiae (EC 2.7.7.4), is an enzyme belonging to the transferase family. This enzyme utilizes ATP and sulfate as substrates and produces diphosphate and adenosine-5'-phosphosulfate as products. It plays a role in three metabolic pathways: purine metabolism, selenoamino acid metabolism, and sulfur metabolism.

α-Glucosidase, Saccharomyces cerevisiae (EC 3.2.1.20), is an enzyme classified as a glucosidase found in the brush border of the small intestine. It acts on 1,4-α-glycosidic bonds to break down starch and disaccharides into glucose.

D-Threonine (H-D-Thr-OH) is a metabolite of Saccharomyces cerevisiae.

Cyclo-L-Trp-L-Trp is a broad-spectrum antifungal. It also induces a high degree of acetylation of histones.

Cycloheximide (Naramycin A) is a natural product . Cycloheximide‘s IC50 values for protein synthesis and RNA synthesis in vivo are 532.5 nM and 2880 nM, respectively. Cycloheximide inhibits ferroptosis and autophagy and is an antifungal antibiotic.

Zymosan A, a polysaccharide derived from Saccharomyces cerevisiae, is a TLR2 agonist that can upregulate ASCL2 through the TLR2 and Wnt signaling pathways, promoting the regeneration of intestinal stem cells (ISCs) after radiation-induced injury. It exhibits significant radioprotective effects, helping to prevent and alleviate IR-induced intestinal damage. Additionally, Zymosan A can induce immune responses, inflammation, anorexia, and elevated body temperature, and is commonly used to establish peritonitis models.

2-Methylbutyl acetate is the acetate ester formally derived from the condensation of acetic acid with 2-methylbutan-1-ol. 2-Methylbutyl acetate is the metabolite of Saccharomyces cerevisiae, it has been reported as a volatile organic compound in Vitis vinifera, Tagetes minuta, and Myrtus communis.

D-(+)-Trehalose (Mycose) can inhibit the decomposition of collagen, so it can be used to improve osteoporosis.

1. Octyl Gallate is an antioxidant approved by the US Food and Drug Administration (FDA) as a food additive. 2. Octyl Gallate has antimetastatic activity. 3. Octyl Gallate shows antimicrobial activity against H. pylori, with a minimum inhibitory concentration (MIC) value of 125 ug/mL. 4. Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.5. Octyl Gallate is a potential anticancer agent, it exhibited decreased MCF-7 & MDA-MB-231 survival and induced apoptosis, with IC50 value of 40 uM. 6. Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) has antiviral activity, it shows an inhibitory effect on the growth of herpes simplex virus type 1 (HSV-1) in HEp-2 or Vero cells. 7. Octyl gallate shows antifungal activity against Saccharomyces cerevisiae ATCC7754 and Zygosaccharomyces bailii ATCC 60483.

D-(+)-Trehalose dihydrate (α,α-Trehalose dihydrate) is a natural α-linked disaccharide formed by an α, α-1, 1-glucoside bond between two α-glucose units.

Ribitol is a pentitol that can be formed by ribose reduction. Enhancement of the D-glucose to pentose phosphate pathway in Saccharomyces cerevisiae can be used to produce ribitol and D-ribose.

Undecanal exhibits inhibitory activity against Saccharomyces cerevisiae ATCC, Candida albicans, and fungi, and is widely used in biochemical experiments and drug synthesis research.

ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.

Ac-BIM-acid bromide is an acridine derivative that effectively inhibits amyloid fibrillization. It modulates the structure of the N-terminal region of the Saccharomyces cerevisiae Stm1 protein (Stm1_N1-113) and the amyloid form of the human Aβ42 protein, thereby impeding their growth. Ac-BIM-acid bromide is applicable in Alzheimer's disease research.

IKE16 is a fungal-selective eukaryotic topoisomerase II inhibitor with an IC50 value of 13.68 μM. It selectively inhibits the DNA relaxation and decatenation activities of yTOPOII. IKE16 shows moderate activity against standard fungal strains [Candida albicans ATCC 10231, Saccharomyces cerevisiae ATCC 89763], with a minimum inhibitory concentration (MIC) of 2 μg/mL for S. cerevisiae ATCC 89763. It exhibits high cytotoxicity to human cells, with EC50 values of 0.07 μM in HepG2 cells and 0.045 μM in HEK-293 cells. IKE16 is utilized in antifungal infection research.

Polygodial (Tadeonal) is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana.

BUR1 is a selective BMP upregulator that acts by increasing the expression of Inhibitor of DNA binding 1 and inducing BMP2 and PTGS2 expression.

NSC-670224 is an inhibitor of histone deacetylases-6 (HDAC6) and nuclear factor-κB (NF-κB) activation blocker. It has been shown to be toxic to Saccharomyces cerevisiae at low micromolar concentrations, potentially acts via a mechanism of action related t

Puntarenine is an alkaloid of the isohomoprotoberberine family that has shown marginal activity against the dermatophytic fungus Trichophyton mentagrophytes and the yeast Saccharomyces cerevisiae.

C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid present in Saccharomyces cerevisiae, wheat grains, and the mammalian epidermal stratum corneum, composed of a phytosphingosine backbone amide-linked to a C18 fatty acid chain, C18 Phytoceramide regulates apoptosis, cell differentiation, smooth muscle cell proliferation, and mitochondrial respiratory chain activity while inhibiting IL-4, TNF-α, c-Jun, and NF-κB expression in histone-stimulated murine skin tissue, supporting its use in dermatological, inflammatory, and cosmetic skin barrier research.

ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms.