Search Result

Search Results for " reperfusion "

Targets

108

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T3102	NS-1619		Apoptosis , Potassium Channel
	NS1619 have cardio-protective effects after ischemia-reperfusion injury.		Apoptosis , Potassium Channel
T9073	SRS16-86		Ferroptosis
	SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.		Ferroptosis
T2058	Palosuran	ACT-058362	GPR
	Palosuran (ACT-058362) (ACT-058362) is a new potent and specific antagonist of the human UT receptor.		GPR
T9765	TJ-M2010-5		MyD88
	TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.		MyD88
T22537	9-Phenanthrol		TRP/TRPV Channel
	9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.		TRP/TRPV Channel
T24109	GSK329	GSK 329,GSK-329	Others
	GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.		Others
T9714	Atpenin A5		Potassium Channel
	Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].		Potassium Channel
T9232	Mitochondrial fusion promoter M1		Mitochondrial Metabolism
	Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...		Mitochondrial Metabolism
T4612	NS309		EGFR , Potassium Channel , HER
	NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat...		EGFR , Potassium Channel , HER
T1677	Montelukast	Singular	Leukotriene Receptor , Lipoxygenase , LTR
	Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury...		Leukotriene Receptor , Lipoxygenase , LTR
T23521	VULM 1457		Acyltransferase
	VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...		Acyltransferase
T1677L	Montelukast sodium	MK0476	Leukotriene Receptor , LTR
	Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver i...		Leukotriene Receptor , LTR
T14186	17-ODYA	Alkynyl Stearic Acid	Others , PROTAC Linker
	17-ODYA (Alkynyl Stearic Acid) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.		Others , PROTAC Linker
T6547	Ipratropium Bromide	Sch 1000,Itrop,Atrovent	AChR
	Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema.		AChR
T1479	Isosorbide dinitrate	Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate	Others , NO Synthase
	Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.		Others , NO Synthase
T12478L	Pinacidil	S 1230,P 1134,S-1230,P-1134,P1134	Potassium Channel
	Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.		Potassium Channel
T2171	SEW2871	SEW2871	S1P Receptor , LPL Receptor
	SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...		S1P Receptor , LPL Receptor
T0098	Ipratropium bromide monohydrate	Ipratropium bromide hydrate	AChR
	Ipratropium bromide monohydrate (Ipratropium bromide hydrate) is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial...		AChR
T6986	Sivelestat	ONO5046,EI546,LY544349	Others , SARS-CoV , Serine Protease
	Sivelestat (ONO5046) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44 nM.		Others , SARS-CoV , Serine Protease
T21334	Bucillamine	DE-019,Thiobutarit,Tiobutarit,SA96,DE 019,DE019	VEGFR , Antioxidant
	Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF. Bucillamine is an orally active sulfhydryl donor and antioxidant with antirheumatic and...		VEGFR , Antioxidant
T3230	NLRP3-IN-2	5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I	NOD-like Receptor (NLR) , NOD
	NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting i...		NOD-like Receptor (NLR) , NOD
T6651	Safinamide mesylate	PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate	MAO , Monoamine Oxidase
	Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.		MAO , Monoamine Oxidase
T3649	BGP-15	BGP15,BGP-15 2HCl	PARP
	BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.		PARP
T23356	Linsidomine hydrochloride	SIN-1 chloride	Others
	Linsidomine hydrochloride (SIN-1 chloride) is considered as a metabolite of moxidomine, with vasodilation, inhibition of platelet aggregation, and antiangina activity. In myocardial ischemia-reperfusion models, Linsidomi...		Others
T60507	Utreloxastat
	Utreloxastat is a compound used to study diseases including alpha-synucleinopathies, tauopathies, ALS, traumatic brain injury, and ischemic-reperfusion related injuries.
T31795	FK-330	LS-192510,FR-260330,FK330,FK 330	NOS
	FK-330 (FR-260330) is a novel orally active inducible nitric oxide synthase inhibitor with potential anticancer and antitumor activity that prevents ischemia and reperfusion injury in rat liver transplantation.		NOS
T13603	CDDO-3P-Im		Necroptosis
	CDDO-3P-Im is an orally active inhibitor of necroptosis with chemopreventive effects. CDDO-3P-Im can be used in studies about ischemia/reperfusion.		Necroptosis
T15049	Daltroban	BM-13505,SKF 96148	PPAR
	Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.		PPAR
T6329	3-Aminobenzamide	3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001	PARP
	3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during reperfusion.		PARP
T34268	Raxofelast	IRFI016,IRFI-016,IRFI 016
	Raxofelast (IRFI-016) is a hydrophilic, non-systemic, vitamin-like antioxidant that reduces ischemia-reperfusion injury in testis. Raxofelast is a good candidate compound for stopping oxidative stress after acute testicu...
T68879	FK-330 dihydrate	FR-260330 dihydrate	NO Synthase
	FK-330 dihydrate（FR-260330 dihydrate） is a novel orally active inducible nitric oxide synthase inhibitor with potential anticancer and antitumor activity to prevent ischemia and reperfusion injury in rat liver transplant...		NO Synthase
T5483	DMX-5804	DMX-5084	MAPK
	DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3 nM.DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice.		MAPK
T9180	LUF6096	CF-602	Adenosine Receptor
	LUF6096 (CF-602) is a potent allosteric enhancer of the adenosine A3 receptor, exhibiting the capability to enhance agonist binding allosterically while demonstrating low orthosteric affinity across adenosine receptors. ...		Adenosine Receptor
T68130	Pobilukast	SKF 104353 Z2,SKF 104353	Leukotriene Receptor
	Pobilukast (SKF 104353) is a selective cysteinyl leukotriene receptor antagonist that blocks phosphatidylinositol metabolism and leukotriene D-induced thromboxane synthesis, and can be used to study limiting myocardial d...		Leukotriene Receptor
T20563	PD-166793	PD-166793-0000,PD 166793,PD166793	MMP
	PD-166793 is an orally active, potent and selective MMP inhibitor with inhibitory effects on MMP-2, MMP-3 and MMP-13.PD-166793 ameliorates myocardial ischemia and reperfusion injury in a rat model of heart failure.PD-166...		MMP
T28978	Tirilazad mesylate	U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate	Antiviral
	Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal c...		Antiviral
T37379	Protectin D1	Neuroprotectin D1,NPD1	Akt , PI3K
	Protectin D1 (Neuroprotectin D1) is a neuroprotectin produced by neuronal cells and is a potential cardioprotective agent.Protectin D1 attenuates myocardial ischemia/reperfusion injury and inhibits imiquimod-induced psor...		Akt , PI3K
T21835	Z-LEHD-fmk		Apoptosis , Caspase
	Z-LEHD-FMK is a selective and potent caspase-9 inhibitor that protects against reperfusion injury and slows apoptosis.Z-LEHD-FMK exhibits antitumor and neuroprotective activity, increases the yield of in vitro-produced p...		Apoptosis , Caspase
T36569	KR-32568		Sodium Channel
	KR-32568 is a sodium/hydrogen exchanger 1 (NHE-1) inhibitor (IC50: 230 nM). KR-32568 exhibits potent cardioprotective effects. When used at a concentration of 10 μM, it restored cardiac systolic function in an isolated i...		Sodium Channel
T38287	C3a Receptor Agonist	C3a receptor agonist 1,Complement 3a Receptor Agonist	Complement System
	C3a Receptor Agonist (C3a receptor agonist 1) binds the G protein-coupled C3a receptors (C3aRs) in the immune system complement pathway. Activation of C3aR prevents neutrophils from being mobilized in a model of intestin...		Complement System
T50098	TIQ-A		PARP
	TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in m...		PARP
T36503	Sodium Hydrogen Sulfide (hydrate)		Others
	Sodium Hydrogen Sulfide (hydrate) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium Hydrogen Sul...		Others
T21967	MEG hemisulfate	Mercaptoethylguanidine hemisulfate	NOS
	MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS i...		NOS
T9948	NecroX-7	LC-280126,LC28-0126,LC28 0126	NADPH-oxidase
	NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing ...		NADPH-oxidase
T33451	ML 7	ML7,ML-7
	ML 7 is an inhibitor of myosin light chain kinase that protects cardiac function from ischemia/reperfusion (I/R) injury.
T38693	TRC160334	TRC160334
	TRC160334 is a hydroxylase inhibitor of hypoxia-inducible factor (HIF). It is employed in research about ischemia/reperfusion injury.
T68878	L-2286
	L-2286 is a novel PARP inhibitor. L-2286 exerted significant protective effect against ischemia-reperfusion-induced myocardial injury in both experimental models. More importantly, L-2286 facilitated the ischemia-reperfu...
T36509	U-74389G	U-74389G,Methylated Tirilazad
	U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4]
T30512	BMS-284640	UNII-XP87V064PV,CHEMBL51879,XP87V064PV
	BMS-284640 is a Na(+)/H(+) exchange agent (NHE) inhibitor that has provided substantial protection in various animal models of myocardial ischemia (MI) and reperfusion in preclinical studies.
T41029	Streptokinase
	Streptokinase is a bacterial protein that acts as a plasminogen activator, commonly employed in the investigation of blood-clotting disorders. Its application extends to enhancing reperfusion blood flow after coronary ar...

Compounds

NS-1619

T3102

Synonym:

Target: Apoptosis, Potassium Channel

Target: TRP/TRPV Channel

GSK329

T24109

Synonym: GSK 329,GSK-329

Target: Potassium Channel

Mitochondrial fusion promoter M1

T9232

Synonym:

Target: Mitochondrial Metabolism

NS309

T4612

Synonym:

Target: EGFR, Potassium Channel, HER

Montelukast

T1677

Synonym: Singular

Target: Leukotriene Receptor, Lipoxygenase, LTR

VULM 1457

T23521

Synonym:

Target: Acyltransferase

Montelukast sodium

T1677L

Synonym: MK0476

Target: Leukotriene Receptor, LTR

17-ODYA

T14186

Synonym: Alkynyl Stearic Acid

Target: Others, PROTAC Linker

Ipratropium Bromide

T6547

Synonym: Sch 1000,Itrop,Atrovent

Target: AChR

Isosorbide dinitrate

T1479

Synonym: Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate

Target: Others, NO Synthase

Pinacidil

T12478L

Synonym: S 1230,P 1134,S-1230,P-1134,P1134

Target: Potassium Channel

SEW2871

T2171

Synonym: SEW2871

Target: S1P Receptor, LPL Receptor

Ipratropium bromide monohydrate

T0098

Synonym: Ipratropium bromide hydrate

Target: AChR

Sivelestat

T6986

Synonym: ONO5046,EI546,LY544349

Target: Others, SARS-CoV, Serine Protease

Bucillamine

T21334

Synonym: DE-019,Thiobutarit,Tiobutarit,SA96,DE 019,DE019

Target: VEGFR, Antioxidant

NLRP3-IN-2

T3230

Synonym: 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I

Target: NOD-like Receptor (NLR), NOD

Safinamide mesylate

T6651

Synonym: PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate

Target: MAO, Monoamine Oxidase

BGP-15

T3649

Synonym: BGP15,BGP-15 2HCl

Target: PARP

Linsidomine hydrochloride

T23356

Synonym: SIN-1 chloride

Synonym: LS-192510,FR-260330,FK330,FK 330

Synonym: BM-13505,SKF 96148

Target: PPAR

3-Aminobenzamide

T6329

Synonym: 3-AB,INO1001,INO-1001,3-ABA,PARP-IN-1,INO 1001

Target: PARP

Raxofelast

T34268

Synonym: IRFI016,IRFI-016,IRFI 016

Target:

FK-330 dihydrate

T68879

Synonym: FR-260330 dihydrate

Target: Adenosine Receptor

Pobilukast

T68130

Synonym: SKF 104353 Z2,SKF 104353

Target: Leukotriene Receptor

PD-166793

T20563

Synonym: PD-166793-0000,PD 166793,PD166793

Target: MMP

Tirilazad mesylate

T28978

Synonym: U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate

Target: Antiviral

Protectin D1

T37379

Synonym: Neuroprotectin D1,NPD1

Target: Apoptosis, Caspase

KR-32568

T36569

Synonym:

Target: Sodium Channel

C3a Receptor Agonist

T38287

Synonym: C3a receptor agonist 1,Complement 3a Receptor Agonist

Target: Complement System

Sodium Hydrogen Sulfide (hydrate)

Synonym: Mercaptoethylguanidine hemisulfate

Target: NOS

NecroX-7

T9948

Synonym: LC-280126,LC28-0126,LC28 0126

Target: NADPH-oxidase

Synonym: U-74389G,Methylated Tirilazad

Target:

BMS-284640

T30512

Synonym: UNII-XP87V064PV,CHEMBL51879,XP87V064PV

Cat No.	Product Name	Synonyms	Targets
T3672	Nomilin		MAPK
	Nomilin is naturally occurring triterpenoids, have immunomodulatory activity.		MAPK
TN1895	Luteolinidin chloride		CD38
	Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.		CD38
T5575	Cycloastragenol	Cyclogalegenol,Astramembrangenin	Epigenetic Reader Domain , Telomerase
	Astramembrangenin (Cycloastragenol (Astramembrangenin)) is a triterpenoid saponin compound and a hydrolysis product of the main active ingredient in Astragalus membranaceus. Cycloastragenol (CAG) may have a novel therape...		Epigenetic Reader Domain , Telomerase
TN6490	Regaloside C		Others
	Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.		Others
T3890	Verbenalin	Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin	Others
	Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.		Others
T2163	Dihydrocapsaicin	CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others , TRP/TRPV Channel
	Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...		Others , TRP/TRPV Channel
TN4661	Nodosin		IL Receptor , Autophagy
	Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp...		IL Receptor , Autophagy
T5S2178	Fargesin	(+/-)-Fargesin	Adrenergic Receptor
	1. Fargesin ((+/-)-Fargesin) as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Fargesin improves dyslipidemia and hyperglycemia by activating...		Adrenergic Receptor
T4S2084	3'-Methoxypuerarin	3’- Methoxy Puerarin	Antioxidant
	3'-Methoxypuerarin shows neuron protection activity, it can protect hippocampal neurons against ischemia/reperfusion injury by inhibiting apoptosis. 3'-Methoxypuerarin(3’- Methoxy Puerarin) has antioxidant activities, it...		Antioxidant
T2S0500	Ilexsaponin A	Ilexsaponin A1	Others
	1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.		Others
T3900	Emodin-8-glucoside	Emodin glucoside B,Anthraglycoside B	Others
	Emodin-8-glucoside (Anthraglycoside B) functions to protect from focal cerebral injury induced by ischemia and reperfusion. Emodin-8-beta-D-glucoside directly stimulates cell proliferation and differentiation of osteobla...		Others
T1208	Citicoline sodium	Citicoline sodium salt,CDP-choline	Apoptosis , Others , Endogenous Metabolite
	Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons...		Apoptosis , Others , Endogenous Metabolite
TN2080	Pinoresinol	(+)-Pinoresinol	Apoptosis , NF-κB , CDK , p53
	Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st...		Apoptosis , NF-κB , CDK , p53
T3388	Calycosin-7-O-β-D-glucoside	calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside	MMP , Reactive Oxygen Species
	Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity. Calycosin 7-O-β-D-glucoside has antimicrobial activity. Calycos...		MMP , Reactive Oxygen Species
T4518	Licochalcone D		ERK , NF-κB
	Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...		ERK , NF-κB
T3893	Forsythoside B		TNF , NF-κB
	Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...		TNF , NF-κB
T3779	Crocin II	Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B	Caspase , COX , NO Synthase
	Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres...		Caspase , COX , NO Synthase
T2973	Astragaloside IV	AST-IV,AS-IV	MMP , ERK , Estrogen/progestogen Receptor , JNK
	Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1/2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cel...		MMP , ERK , Estrogen/progestogen Receptor , JNK
T4S0280	Eleutheroside D
	Eleutheroside has protective effect to myocardial ischemic-reperfusion injury(IRI) in isolated rats.
TN1618	Erigeroside		Others
	Erigeroside has the protective effects on cerebral ischemia-reperfusion injury in rat, its ability of anti-oxidation and scavenging oxidation free radical may be one of its protective mechanisms.		Others
TN1431	Baohuoside VII		Others
	Baohuoside aglycone possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. Baohuoside VI...		Others
TN3914	Echinatine		ATPase , IL Receptor , TNF
	Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin c...		ATPase , IL Receptor , TNF
TN1875	Liriodenine		BCL , Caspase , p53
	Liriodenine is a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro, it has antitumor, antibacterial and antifungal activities, it can suppress ventricular arrhythmias induced by myocardial isch...		BCL , Caspase , p53
T36448	(E)-Ajoene
	(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fu...

Natural Products

Luteolinidin chloride

Synonym: Cyclogalegenol,Astramembrangenin

Target: Epigenetic Reader Domain, Telomerase

Synonym: Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin

Target: Others

Dihydrocapsaicin

T2163

Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Target: Others, TRP/TRPV Channel

Nodosin

TN4661

Synonym:

Target: IL Receptor, Autophagy

Fargesin

T5S2178

Synonym: (+/-)-Fargesin

Target: Adrenergic Receptor

3'-Methoxypuerarin

T4S2084

Synonym: 3’- Methoxy Puerarin

Target: Antioxidant

Ilexsaponin A

T2S0500

Synonym: Ilexsaponin A1

Target: Others

Emodin-8-glucoside

T3900

Synonym: Emodin glucoside B,Anthraglycoside B

Target: Others

Citicoline sodium

T1208

Synonym: Citicoline sodium salt,CDP-choline

Target: Apoptosis, Others, Endogenous Metabolite

Pinoresinol

TN2080

Synonym: (+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

Calycosin-7-O-β-D-glucoside

T3388

Synonym: calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside

Target: MMP, Reactive Oxygen Species

Synonym: Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B

Target: Caspase, COX, NO Synthase

Astragaloside IV

T2973

Synonym: AST-IV,AS-IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

Target: ATPase, IL Receptor, TNF

Liriodenine

TN1875

Synonym:

Target: BCL, Caspase, p53

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04815	C1 inhibitor Protein, Rat, Recombinant (His)	Rat	HEK293
	Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact s...
TMPY-05053	ANGPTL2 Protein, Human, Recombinant (His)	Human	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-00653	Complement C5 Protein, Human, Recombinant (Complement C5a)	Human	E. coli
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-04726	IL-8/CXCL8 Protein, Human, Recombinant (His)	Human	Yeast
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-05057	Complement C5 Protein, Human, Recombinant (His & FLAG)	Human	HEK293
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-00472	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)	Human	E. coli
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-00754	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)	Human	HEK293
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-04902	Complement C5a Protein, Mouse, Recombinant	Mouse	E. coli
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-04424	MST3 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis pla...
TMPJ-00082	NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes w...
TMPY-01183	C1 inhibitor Protein, Human, Recombinant (His)	Human	HEK293
	Plasma protease C1 inhibitor, also known as C1-inhibiting factor, C1-INH, C1 esterase inhibitor, SERPING1 and C1IN, is a serine proteinase inhibitor (serpin) that regulates activation of both the complement and contact s...
TMPY-03998	ANGPTL2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-06814	Complement C5 Protein, Human, Recombinant (Flag)	Human	HEK293
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-06137	Complement C5 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-03480	IL-8/CXCL8 Protein, Rhesus, Recombinant	Rhesus	E. coli
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-00753	IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc)	Human	HEK293
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-03022	IL-8/CXCL8 Protein, Canine, Recombinant	Canine	E. coli
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-00755	IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)	Human	HEK293
	Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proang...
TMPY-06538	Complement C5 Protein, Cynomolgus, Recombinant	Cynomolgus	HEK293
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...
TMPY-05459	Complement C5a Protein, Mouse, Recombinant, Biotinylated	Mouse	E. coli
	C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway...

C1 inhibitor Protein, Rat, Recombinant (His)

TMPY-04815

Species: Rat

Expression System: HEK293

ANGPTL2 Protein, Human, Recombinant (His)

TMPY-05053

Species: Human

Expression System: HEK293

Complement C5 Protein, Human, Recombinant (Complement C5a)

TMPY-00653

Species: Human

Expression System: E. coli

IL-8/CXCL8 Protein, Human, Recombinant (His)

TMPY-04726

Species: Human

Expression System: Yeast

Complement C5 Protein, Human, Recombinant (His & FLAG)

TMPY-05057

Species: Human

Expression System: HEK293

IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)

TMPY-00472

Species: Human

Expression System: E. coli

IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)

TMPY-00754

Species: Human

Expression System: HEK293

Complement C5a Protein, Mouse, Recombinant

TMPY-04902

Species: Mouse

Expression System: E. coli

MST3 Protein, Human, Recombinant (His)

TMPY-04424

Species: Human

Expression System: Baculovirus-Insect Cells

NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)

TMPJ-00082

Species: Mouse

Expression System: Human Cells

C1 inhibitor Protein, Human, Recombinant (His)

TMPY-01183

Species: Human

Expression System: HEK293

ANGPTL2 Protein, Mouse, Recombinant (hFc)

TMPY-03998

Species: Mouse

Expression System: HEK293

Complement C5 Protein, Human, Recombinant (Flag)

TMPY-06814

Species: Human

Expression System: HEK293

Complement C5 Protein, Cynomolgus, Recombinant (His)

TMPY-06137

Species: Cynomolgus

Expression System: HEK293

IL-8/CXCL8 Protein, Rhesus, Recombinant

TMPY-03480

Species: Rhesus

Expression System: E. coli

IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc)

TMPY-00753

Species: Human

Expression System: HEK293

IL-8/CXCL8 Protein, Canine, Recombinant

TMPY-03022

Species: Canine

Expression System: E. coli

IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc)

TMPY-00755

Species: Human

Expression System: HEK293

Complement C5 Protein, Cynomolgus, Recombinant

TMPY-06538

Species: Cynomolgus

Expression System: HEK293

Complement C5a Protein, Mouse, Recombinant, Biotinylated

TMPY-05459

Species: Mouse

Expression System: E. coli

Cat No.	Product Name
L8700	Ferroptosis Compound Library		800 compounds
	A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；

Libraries

Ferroptosis Compound Library

L8700

Compounds: 800