r 140

IDH2R140Q-IN-2 is an orally active and potent IDH2R140Q inhibitor with an IC50 of 29 nM.IDH2R140Q-IN-2 possesses potential antitumour activity, reducing D2HG production in TF-1 cell lines carrying the IDH2R140Q mutation (IC50 of 10 nM) and inhibiting tumour tissue D2HG levels.IDH2R140Q-IN-2 is suitable for the study of acute myeloid leukaemia (AML).

IDH2R140Q-IN-1 is a potent inhibitor of IDH2R140Q (IC50: 6.1 nM) and can be used in studies of acute myeloid leukemia.

(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.

SR 140333 is a NK1 receptor antagonist.

Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.

Compound Fr14002, with CAS No. 873-32-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14002 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14006, with CAS No. 394-32-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14006 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14009, with CAS No. 35700-40-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14009 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14010, with CAS No. 153912-60-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14010 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14012, with CAS No. 939-23-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14012 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14017, with CAS No. 94-08-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14017 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14019, with CAS No. 17635-45-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14019 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14020, with CAS No. 1670-81-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14020 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14022, with CAS No. 100859-84-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14022 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14023, with CAS No. 74470-23-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14023 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14024, with CAS No. 54454-10-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14024 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14025, with CAS No. 2749-59-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14025 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14026, with CAS No. 6947-94-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14026 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14028, with CAS No. 17334-08-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14028 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14029, with CAS No. 1072-84-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14029 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14034, with CAS No. 95-14-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14034 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14036, with CAS No. 27489-62-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14036 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14037, with CAS No. 4187-56-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14037 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14038, with CAS No. 5470-70-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14038 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.