phenolic

Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified as an endocrine disruptor. It has been linked to many diseases, including respiratory disease, cardiovascular disease, diabetes, kidney disease, obesity and reproductive disorders.

Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Clovamide is a potent antioxidantand that has shown neuroprotective effects (EC50s = 0.9-3.7 µM) in several in vitro models of neuronal death. Trans-Clovamide is an excellent ROS and oxygen radical scavenger and also has anti-inflammatory and neuroprotective effects. Clovamide is an anti-microbial with activity against the human pathogens influenza A subtype H5N1, Trypanosoma evansi, and Heliobacter pylori.

Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.

Methyl 5-hydroxypyridine-2-carboxylate, a phenolic acid identified in the stems of Mahonia fortune, demonstrates in vitro inhibitory effects on nitric oxide (NO) production.

Parishin (Parishin A) A is isolated from the rhizomes of Gastrodia elata. It has good neuroprotective effects against brain disorders.

Cephaeline was highly active against protected primary CLL cells (relative IC50's 35nM ) and acted by repressing HIF-1α± and disturbing intracellular redox homeostasis.

Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.

Phenolic acid is an endogenous metabolite.

Mycophenolic acid phenolic β-D-glucoside is a biochemical reagent used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the function of glycans in biological systems. This field is closely linked to basic research, biomedicine, and biotechnology.

Salvianolic acid A (Dan Phenolic Acid A) is a natural product and an inhibitor of matrix metalloproteinase 9 (MMP-9). Salvianolic acid A has antioxidant and anti-inflammatory activity and protects the blood-brain barrier.

Methyl 2,4-dihydroxyphenylacetate is a natural product isolated from Nigella damascena seeds with selective phytotoxic effects.

VH 101, phenol is a VHL ligand based on VH032. It is able to utilize linkers to ligands of target proteins to yield PROTAC molecules such as PROTAC 1. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.

Theaflavin digallate and lactic acid together could reduce herpes simplex virus transmission.

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Mycophenolic acid-D3 is a derivative of Mycophenolic acid. Mycophenolic acid (T1335) is a compound that reduces GTP level and impacts transcription elongation of RNA polymerase II (RNAP II), promotes proximal site use and reverses the effect of cordyceps on selective polyadenylation.

Mycophenolic acid IV is a useful organic compound for research related to life sciences. The catalog number is T124275 and the CAS number is 74838-16-7.

Mycophenolic acid acyl-β-D-glucuronide (Acyl-MPAG) is a metabolite of mycophenolic acid (an immunosuppressant).

Mycophenolic Acid Impurity (5,7-dihydroxy-4-methylphthalide) is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part of triple therapy including a calcineurin inhibitor (ciclosporin or tacrolimus) and prednisolone. It is also useful in research for the selection of animal cells that express the E. coli gene coding for XGPRT (xanthine guanine phosphoribosyltransferase).

Mycophenolic acid glucuronide is the glucuronide metabolite of mycophenolic acid in human plasma.

Mycophenolic acid sodium is a potent uncompetitive inhibitor of inosine monophosphate dehydrogenase (IMPDH), exhibiting an EC50 value of 0.24 μM. Mycophenolic acid sodium demonstrates broad antiviral activity against RNA viruses, including influenza. Mycophenolic acid sodium additionally exhibits immunosuppressive, antiangiogenic, and antitumor activities. Mycophenolic acid sodium is widely utilized in virology, immunology, angiogenesis, and cancer biology research involving nucleotide biosynthesis regulation.

Mycophenolic Acid-D3 Phenyl Glucuronide is a deuterated compound of Mycophenolic Acid Phenyl Glucuronide. Mycophenolic Acid Phenyl Glucuronide (T60104) has a CAS number of 31528-44-6. Mycophenolic acid glucuronide is the glucuronide metabolite of mycophenolic acid in human plasma.

Mycophenolic acid-13C-D3 the 13C and deuterated compound of Mycophenolic acid (T1335). Mycophenolic acid has a CAS number of 24280-93-1. Mycophenolic acid is an inosine monophosphate dehydrogenase (IMPDH) inhibitor with anti-proliferative activity.

Mycophenolic acid (Standard) is the standard substance of Mycophenolic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Mycophenolic acid-β-D-glucuronide (Standard) is a reference standard for research and analysis in studies involving Mycophenolic acid-β-D-glucuronide. Mycophenolic acid glucuronide is the glucuronide metabolite of mycophenolic acid in human plasma.