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Search Results for " paroxysmal "

Targets

7

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9189 Iptacopan hydrochloride Iptacopan HCl,LNP023 hydrochloride Complement System
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity b...
T76867 Ravulizumab ALXN1210 Complement System
Ravulizumab (ALXN1210) is a humanized monoclonal antibody targeting complement factor 5 that specifically binds to human complement protein C5 with high affinity to block complement activation. Ravulizumab can be used fo...
T15257 Etripamil MSP-2017,(-)-MSP-2017 Calcium Channel
Etripamil (MSP-2017) displays atrioventricular nodal conduction and prolongs atrioventricular nodal refractory periods by inhibiting calcium ion influx through the calcium slow channels in the atrioventricular node cells...
T8509 Danicopan ACH-4471 Complement System
Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the ...
T21391 Flecainide Tambocor,Apocard,Flecainida,Flecainidum
Flecainide acetate is a class Ic antiarrhythmic agent, it is used to treat a variety of cardiac arrhythmias including paroxysmal atrial fibrillation, paroxysmal supraventricular tachycardia, and ventricular tachycardia. ...
T77190 Crovalimab
Crovalimab (SKY59; RO7112689) is a novel humanized antibody against C5 in a pH-dependent manner with KDs of 15.2 nM and 16.8 μM at pH 7.4 and 5.8, respectively. Crovalimab binds human FcRn with great affinity (KD: 17 μM ...
T64692 AMY-101 acetate
Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exe...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02503 CD59a Protein, Mouse, Recombinant (hFc) Mouse HEK293
Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 f...
TMPY-02266 CD59a Protein, Mouse, Recombinant (His) Mouse HEK293
Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 f...
TMPY-01854 DPP10 Protein, Human, Recombinant (His) Human HEK293
Inactive dipeptidyl peptidase 1, also known as Dipeptidyl peptidase IV-related protein 3, Dipeptidyl peptidase X, Dipeptidyl peptidase-like protein 2, DPRP-3, DPL2 and DPP1, is a single-pass type II membrane protein w...
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