Search Result

Search Results for " osteoblast "

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T81593	Osteoblast-Adhesive Peptide
	Osteoblast-Adhesive Peptide, a polypeptide designed for biomaterials' chemical modification, enhances osteoblast adhesion, showing promise for use in dentistry and orthopedics [1] [2].
T39508	KY-02327		Others
	KY-02327, a metabolically stabilized analog of KY-02061, serves as a potent inhibitor of the Dishevelled (Dvl)-CXXC5 interaction. This compound activates the Wnt/β-catenin pathway, thereby promoting osteoblast differenti...		Others
T7844	4-IPP	4-Iodo-6-phenylpyrimidine	Others
	4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF)		Others
T16159	Muramyl dipeptide	MDP	NOD
	Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide indirectly decreases osteoclast differentiation...		NOD
T8550	NDMC101		Others , NF-κB , Proteasome
	NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity.		Others , NF-κB , Proteasome
T1810	Purmorphamine	Shh Signaling Antagonist VI	Hedgehog/Smoothened , Smo , Autophagy
	Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo. It also is an inducer of osteoblast differentiation.		Hedgehog/Smoothened , Smo , Autophagy
T22767	ER 50891		Retinoid Receptor
	ER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast differentiation induced by bone morphogenetic protein 2.		Retinoid Receptor
T11048L	DIPQUO hydrochloride	DIPQUO hydrochloride(1269365-82-3 Free base)	Phosphorylase
	DIPQUO hydrochloride is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO hydrochloride promotes mouse and human osteoblast differentiation via activation of p38 M...		Phosphorylase
T60554	Schnurri-3 inhibitor-1		Others
	Schnurri-3 inhibitor-1, a potent inhibitor of schnurri-3, is an essential regulator of bone formation in adults that can be used in osteoporosis research. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in...		Others
TP1345	Kisspeptin-10, human (TFA)(374675-21-5,FREE)		GPR , Kisspeptin
	Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role i...		GPR , Kisspeptin
T27999	MDK-4624	AMPKα1 activator C13,C13, Compound 13
	MDK-4624 is a AMPKα1 activator. MDK-4624 inhibits Helicobacter pylori-induced oxidative stresses and gastric epithelial cell apoptosis. MDK-4624 attenuates dexamethasone-induced osteoblast cell death. MDK-4624 potently i...
T72008	E09241
	E09241 is a novel OPG/RANKL upregulator, increasing OPG expression without affecting RANKL expression, promoting osteoblast differentiation while inhibiting osteoclast differentiation, regulating OPG expression through c...
T71904	Chlormadinone (free base)
	Chlormadinone (free base) is a synthetic steroid hormone and antagonist at androgen and estrogen receptors used to treat BPH and polycystic ovary syndrome. It also promotes osteoblast differentiation and Ca deposition in...
T69656	E197
	E197 is a DOCK5 inhibitor. E197 can inhibit both mouse and human osteoclast activity. In particular, E197 prevented pathological bone loss in mice. Most interestingly, treatment with E197 did not affect osteoclast and os...
T62436	KY-02327 acetate
	KY-02327 acetate is a potent inhibitor of Dishevelled (Dvl)-CXXC5 interactions and is a metabolically stable analog of KY-02061. KY-02327 acetate activates the Wnt/β-catenin pathway, which in turn promotes osteoblast dif...
T71284	Glimepiride urethane
	Glimepiride urethane is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, glimepiride increases the activity of intracellular insulin receptors. Gli...
T36080	Rivenprost	ONO-4819
	Prostaglandin E2 activates four distinct G protein-coupled receptors, EP1-4. Rivenprost is a potent and selective agonist for the EP4 receptor (Ki = 0.7, 56, 620, and >10,000 nM for EP4, EP3, EP2, and EP1, respectively)....
T75745	Kisspeptin-10, human TFA
	Kisspeptin-10, human TFA, is a potent vasoconstrictor and angiogenesis inhibitor that also suppresses tumor metastasis through its interaction with the receptor GPR54. It is crucial for embryonic kidney development and p...
T35604	Osteocalcin (1-49) (human) (trifluoroacetate salt)
	Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D ...
T83848	VnP-16 TFA
	VnP-16, a synthetic peptide fragment mirroring amino acids 270-281 of vitronectin (a multifunctional glycoprotein involved in cell attachment, migration, and spreading), promotes attachment and spreading of isolated huma...

Compounds

Osteoblast-Adhesive Peptide

Synonym: 4-Iodo-6-phenylpyrimidine

Target: Others, NF-κB, Proteasome

Purmorphamine

T1810

Synonym: Shh Signaling Antagonist VI

Target: Hedgehog/Smoothened, Smo, Autophagy

ER 50891

T22767

Synonym:

Target: Retinoid Receptor

DIPQUO hydrochloride

T11048L

Synonym: DIPQUO hydrochloride(1269365-82-3 Free base)

Target: Phosphorylase

Schnurri-3 inhibitor-1

T60554

Synonym:

Target: Others

Kisspeptin-10, human (TFA)(374675-21-5,FREE)

TP1345

Synonym:

Target: GPR, Kisspeptin

MDK-4624

T27999

Synonym: AMPKα1 activator C13,C13, Compound 13

Chlormadinone (free base)

Kisspeptin-10, human TFA

T75745

Synonym:

Target:

Osteocalcin (1-49) (human) (trifluoroacetate salt)

Cat No.	Product Name	Synonyms	Targets
TN5888	Toddaculin		Others
	Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-κB, ERK 1/2, and p38 MAPK signaling pathways, but can in...		Others
T2771	Orcinol glucoside	Sakakin	Antioxidant
	Orcinol glucoside (Sakakin) (OG), an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn, shows potent antioxidative and anxiolytic activities without sedative effects.		Antioxidant
T2848	Osthole	Osthol,NSC 31868,Ostol	Apoptosis , HBV , Parasite , Histamine Receptor
	Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.		Apoptosis , HBV , Parasite , Histamine Receptor
T13768	(+)-Medicarpin		Estrogen/progestogen Receptor
	(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium flo...		Estrogen/progestogen Receptor
T3488	Tectorigenin	4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine	Apoptosis
	Tectorigenin (4',5,7-Trihydroxy-6-methoxyisoflavone) is an O-methylated isoflavone. Tectorigenin Promotes Osteoblast Differentiation and in vivo Bone Healing, but Suppresses Osteoclast Differentiation and in vivo Bone Re...		Apoptosis
T3925	Astragaloside I	Cyclosieversioside B,Astrasieversianin IV	Wnt/beta-catenin
	Astragaloside I (Cyclosieversioside B) is a natural product isolated from Astragalus membranaceus. It can stimulate osteoblast differentiation through the Wnt/β-catenin signaling pathway and can be used to study osteogen...		Wnt/beta-catenin
T6S1559	Aurantio-obtusin		Others
	1. Biotransformation of glucoAurantio-obtusin towards Aurantio-obtusin increased the toxicity of irinotecan through increased inhibition of SN-38 glucuronidation. 2. Aurantio-obtusin, stimulated chemotactic migration of ...		Others
TN1918	Medicarpin		Apoptosis , BCL , ROS , JNK
	Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERα², promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in add...		Apoptosis , BCL , ROS , JNK
T10109	3-Carene	Delta-3-Carene	COX , Antifungal
	3-Carene（Delta-3-Carene） is a bicyclic monoterpene extracted from western larch and Douglas-fir that acts as a phytofungicide.3-Carene inhibits inflammatory infiltrates and COX-2 overexpression induced by nociceptive sti...		COX , Antifungal
T3S2312	Poncirin	Isosakuranetin-7-neohesperidoside	Apoptosis , Others
	1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha...		Apoptosis , Others
T4915	β-Glycerophosphate disodium salt hydrate		Phosphatase , Endogenous Metabolite
	β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It func...		Phosphatase , Endogenous Metabolite
T4S1943	Kirenol	Kirel	Wnt/beta-catenin
	1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid...		Wnt/beta-catenin
TN6926	Paeonoside		Others
	Paeonoside, found in P. suffruticosa, is biologically active and can promote wound healing and migration during osteoblast differentiation. Paeonoside has certain antidiabetic activity and may prevent sepsis and death fr...		Others
TMA0132	Dihydrophaseic acid		Others
	Dihydrophaseic acid 3'-O-b-D-glucopyranoside (D3G) can increase the proliferation and differentiation of osteoblast cells and enhance bone formation, suggests that D3G may be a good candidate for the treatment of osteopo...		Others
TN2830	26-Nor-8-oxo-alpha-onocerin		Others
	26-Nor-8-oxo-alpha-onocerin can promote the osteoblast proliferation rate, the effect is time-dependent,concentration-dependent and differentiation state-dependent.		Others
TN3552	Byzantionoside B		Others
	Byzantionoside B shows stimulatory activity on human osteoblast cells, it may have the potential to stimulate bone formation and regeneration.		Others
TN1265	3'-O-Methylorobol	3'-O-METHYLOROBOL	Others
	3'-O-Methylorobol exhibits moderate antioxidant activity in the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging assay, it also exerts potential analgesic properties. 3'-O-Methylorobol can increase osteoblast differ...		Others
T14368	Azadirachtin B		Others
	Azadirachtin B, a limonoid derived from the seed kernels of Azadirachta indica, exhibits a broad spectrum of biochemical activities, including insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral, and oste...		Others
TN4594	Murraol		Antifection
	Murraol shows the significant proliferative activities on osteoblast-like UMR106 cells lines at the concentration of 1 × 10-10 mol/L. It and auraptenol show 63 ug/mL MIC value against Klebsiella pneumoniae ATCC 4352 and ...		Antifection
TN5086	Syringetin		Others
	Syringetin, a flavonoid derivative found in grapes and wine, promotes melanogenesis in B16F10 cells and inhibits osteoblast-mediated osteoclastogenesis in human lung adenocarcinoma.		Others
T81987	Kanzonol D
	Kanzonol D, a flavonoid derived from the hairy root cultures of Glycyrrhiza glabra [1], exhibits anti-inflammatory and anticancer properties by inhibiting nitric oxide production and suppressing NF-κB activation. It also...
TN4394	Kobophenol A		MMP , BCL , p38 MAPK , NF-κB , ROS , DNA/RNA Synthesis , CDK , JNK
	Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell death. Kobophenol A inhibits AChE activity in a dose-depen...
TN1778	Isoformononetin		IL Receptor , Antifection
	Isoformononetin shows fungitoxic activity against Cladosporium sphaerospermum; it also has immunomodulatory activity, it inhibits the differentiation of Th17 cells and B-cell lymphopoesis to promote osteogenesis in estro...		IL Receptor , Antifection

Natural Products

Synonym: Osthol,NSC 31868,Ostol

Target: Apoptosis, HBV, Parasite, Histamine Receptor

(+)-Medicarpin

T13768

Synonym:

Target: Estrogen/progestogen Receptor

Tectorigenin

T3488

Synonym: 4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine

Target: Apoptosis

Astragaloside I

T3925

Synonym: Cyclosieversioside B,Astrasieversianin IV

Target: Wnt/beta-catenin

Target: Apoptosis, BCL, ROS, JNK

3-Carene

T10109

Synonym: Delta-3-Carene

Target: COX, Antifungal

Poncirin

T3S2312

Synonym: Isosakuranetin-7-neohesperidoside

Target: Apoptosis, Others

β-Glycerophosphate disodium salt hydrate

T4915

Synonym:

Target: Phosphatase, Endogenous Metabolite

Kirenol

T4S1943

Synonym: Kirel

Target: Wnt/beta-catenin

26-Nor-8-oxo-alpha-onocerin

Synonym: 3'-O-METHYLOROBOL

Target: MMP, BCL, p38 MAPK, NF-κB, ROS, DNA/RNA Synthesis, CDK, JNK

Isoformononetin

TN1778

Synonym:

Target: IL Receptor, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01020	Periostin/OSF-2 Protein, Human, Recombinant (His)	Human	HEK293
	Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-01613	Periostin/OSF-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPJ-01267	CDH11 Protein, Human, Recombinant (His)	Human	Human Cells
	Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in...
TMPJ-01266	CDH11 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
	Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins inte...
TMPK-00587	CDH11 Protein, Human, Recombinant (aa 54-617, His)	Human	HEK293
	CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was...
TMPJ-01051	Pleiotrophin/PTN Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein，Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or...
TMPH-02569	WISP2/CCN5 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPJ-01466	Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)	Human	Human Cells
	TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ...
TMPY-03014	Osteoactivin/GPNMB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPY-00680	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)	Human,Mouse,Rat,Rhesus,Canine	HEK293
	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-02575	PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPY-00423	FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)	Human	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-04487	Osteomodulin Protein, Human, Recombinant (His)	Human	HEK293
	Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein that belongs to the small leucine-rich proteoglycan (SLRP) family and...
TMPY-03357	FGFR2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00972	FGFR2 Protein, Human, Recombinant (His & hFc)	Human	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-02010	DMP1 Protein, Human, Recombinant (His)	Human	HEK293
	Dentin matrix acidic phosphoprotein (DMP1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of b...
TMPH-02128	SMOC1 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Plays essential roles in both eye and limb development. Probable regulator of osteoblast differentiation.
TMPH-02570	WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play an important role in modulating bone turnover. Promotes the adhesion of osteoblast cells and inhibits the binding of fibrinogen to integrin receptors. In addition, inhibits osteocalcin production.
TMPH-01016	GDF-10 Protein, Human, Recombinant (His)	Human	E. coli
	Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis.
TMPH-01338	Fibronectin Protein, Human, Recombinant (His)	Human	E. coli
	Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell s...
TMPY-01783	SMOC1 Protein, Human, Recombinant (His)	Human	HEK293
	SPARC-related modular calcium-binding protein 1, also known as secreted modular calcium-binding protein 1 and SMOC1, is a member of the SPARC family. SMOC1 is widely expressed in many tissues with a strongest signal in o...
TMPH-01014	BMP-2 Protein, Human, Recombinant (His)	Human	E. coli
	Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cardiogenesis, neurogenesis, and osteogenesis. Induces cartilage and bone formation. Initiates the canonical...
TMPY-03402	Osteoactivin/GPNMB Protein, Human, Recombinant (hFc)	Human	HEK293
	GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPY-02143	Osteoactivin/GPNMB Protein, Human, Recombinant (His)	Human	HEK293
	GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPK-00657	SPARC Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM40) is one of the most abundant non-collagenous protein expressed in mineralized tissues.The capacity of SPARC to influence pathways involved in extracell...
TMPH-02240	TMEM119 Protein, Human, Recombinant (hFc)	Human	HEK293
	Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an...
TMPH-02864	Wnt1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Ligand for members of the frizzled family of seven transmembrane receptors. Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. In some developmental processes, is ...
TMPY-00960	ACP5 Protein, Human, Recombinant (His)	Human	HEK293
	Tartrate-resistant acid phosphatase (TRACP) or acid phosphatase 5, tartrate resistant (ACP5 or TRAP) is a glycosylated monomeric metalloenzyme expressed in mammals. TRACP is associated with osteoblast migration to bone r...
TMPY-01414	ACP5 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tartrate-resistant acid phosphatase (TRACP) or acid phosphatase 5, tartrate resistant (ACP5 or TRAP) is a glycosylated monomeric metalloenzyme expressed in mammals. TRACP is associated with osteoblast migration to bone r...
TMPY-03297	BMP-2 Protein, Danio rerio (zebrafish), Recombinant	Danio rerio (zebrafish)	E. coli
	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-01136	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant	Human,Mouse,Rat,Rhesus,Canine	E. coli
	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokin...
TMPY-04899	OGN/Osteoglycin Protein, Human, Recombinant (His)	Human	HEK293
	OGN (Osteoglycin) is a Protein Coding gene. This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. It belongs to the small leucine-rich proteoglycan (SLRP) family. The encoded protei...
TMPJ-01369	DPT Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growth...
TMPH-00274	IGF2/IGF-II Protein, Bovine, Recombinant (hFc)	Bovine	Yeast
	The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved ...
TMPY-01724	Osteoprotegerin Protein, Human, Recombinant (His)	Human	HEK293
	Osteoprotegerin or TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds t...
TMPY-03323	Osteoprotegerin Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	Osteoprotegerin or TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds t...
TMPJ-01211	EDA2R Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Tumor necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR superfamily. EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats ...
TMPY-04509	Osteoprotegerin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Osteoprotegerin or TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds t...
TMPY-05262	Osteoprotegerin Protein, Human, Recombinant (hFc)	Human	Baculovirus-Insect Cells
	Osteoprotegerin or TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds t...
TMPH-01900	DDX5 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop r...
TMPY-03389	FGFR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-01228	FGFR2 Protein, Human, Recombinant (aa 1-377, His)	Human	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-01472	Osteomodulin Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Osteomodulin (OMD), also known as Osteoadherin (OSAD), Keratan sulfate proteoglycan osteomodulin, KSPG osteomodulin, and SLRR2C, is a secreted protein that belongs to the small leucine-rich proteoglycan (SLRP) family and...
TMPY-04390	FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)	Human	Baculovirus-Insect Cells
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-04273	FGFR2 Protein, Human, Recombinant (aa 1-378, His)	Human	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-00351	FGFR2 Protein, Human, Recombinant (beta IIIc, His)	Human	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-06321	FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated	Human	HEK293
	FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPY-03046	APCDD1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, res...
TMPJ-00521	CHL2 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse Chordin-Like 2, also known as CHL2, is a novel chordin family member with structural homology to CHL1 which is implicated in tumor angiogenesis. The mouse CHL2 gene encodes a 426 amino acids (aa) protein with a 25...
------------------------ More ------------------------

Periostin/OSF-2 Protein, Human, Recombinant (His)

TMPY-01020

Species: Human

Expression System: HEK293

Periostin/OSF-2 Protein, Mouse, Recombinant (His)

TMPY-01613

Species: Mouse

Expression System: HEK293

CDH11 Protein, Human, Recombinant (His)

TMPJ-01267

Species: Human

Expression System: Human Cells

CDH11 Protein, Human, Recombinant (hFc & His)

TMPJ-01266

Species: Human

Expression System: Human Cells

CDH11 Protein, Human, Recombinant (aa 54-617, His)

TMPK-00587

Species: Human

Expression System: HEK293

Pleiotrophin/PTN Protein, Mouse, Recombinant (His)

TMPJ-01051

Species: Mouse

Expression System: Human Cells

WISP2/CCN5 Protein, Mouse, Recombinant (His)

TMPH-02569

Species: Mouse

Expression System: Yeast

Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)

TMPJ-01466

Species: Human

Expression System: Human Cells

Osteoactivin/GPNMB Protein, Mouse, Recombinant (His)

TMPY-03014

Species: Mouse

Expression System: HEK293

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

TMPY-00680

Species: Human,Mouse,Rat,Rhesus,Canine

Expression System: HEK293

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

TMPY-02575

Species: Human

Expression System: Baculovirus-Insect Cells

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

TMPJ-00662

Species: Human

Expression System: E. coli

FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)

TMPY-00423

Species: Human

Expression System: HEK293

Osteomodulin Protein, Human, Recombinant (His)

TMPY-04487

Species: Human

Expression System: HEK293

FGFR2 Protein, Mouse, Recombinant (hFc)

TMPY-03357

Species: Mouse

Expression System: HEK293

FGFR2 Protein, Human, Recombinant (His & hFc)

TMPY-00972

Species: Human

Expression System: HEK293

DMP1 Protein, Human, Recombinant (His)

TMPY-02010

Species: Human

Expression System: HEK293

SMOC1 Protein, Human, Recombinant (GST & His)

TMPH-02128

Species: Human

Expression System: E. coli

WISP2/CCN5 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02570

Species: Mouse

Expression System: E. coli

GDF-10 Protein, Human, Recombinant (His)

TMPH-01016

Species: Human

Expression System: E. coli

Fibronectin Protein, Human, Recombinant (His)

TMPH-01338

Species: Human

Expression System: E. coli

SMOC1 Protein, Human, Recombinant (His)

TMPY-01783

Species: Human

Expression System: HEK293

BMP-2 Protein, Human, Recombinant (His)

TMPH-01014

Species: Human

Expression System: E. coli

Osteoactivin/GPNMB Protein, Human, Recombinant (hFc)

TMPY-03402

Species: Human

Expression System: HEK293

Osteoactivin/GPNMB Protein, Human, Recombinant (His)

TMPY-02143

Species: Human

Expression System: HEK293

SPARC Protein, Cynomolgus, Recombinant (His)

TMPK-00657

Species: Cynomolgus

Expression System: HEK293

TMEM119 Protein, Human, Recombinant (hFc)

TMPH-02240

Species: Human

Expression System: HEK293

Wnt1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02864

Species: Mouse

Expression System: E. coli

ACP5 Protein, Human, Recombinant (His)

TMPY-00960

Species: Human

Expression System: HEK293

ACP5 Protein, Mouse, Recombinant (His)

TMPY-01414

Species: Mouse

Expression System: HEK293

BMP-2 Protein, Danio rerio (zebrafish), Recombinant

TMPY-03297

Species: Danio rerio (zebrafish)

Expression System: E. coli

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

TMPY-01136

Species: Human,Mouse,Rat,Rhesus,Canine

Expression System: E. coli

OGN/Osteoglycin Protein, Human, Recombinant (His)

TMPY-04899

Species: Human

Expression System: HEK293

DPT Protein, Mouse, Recombinant (hFc)

TMPJ-01369

Species: Mouse

Expression System: Human Cells

IGF2/IGF-II Protein, Bovine, Recombinant (hFc)

TMPH-00274

Species: Bovine

Expression System: Yeast

Osteoprotegerin Protein, Human, Recombinant (His)

TMPY-01724

Species: Human

Expression System: HEK293

Osteoprotegerin Protein, Rhesus, Recombinant (hFc)

TMPY-03323

Species: Rhesus

Expression System: HEK293

EDA2R Protein, Mouse, Recombinant (His)

TMPJ-01211

Species: Mouse

Expression System: Human Cells

Osteoprotegerin Protein, Mouse, Recombinant (hFc)

TMPY-04509

Species: Mouse

Expression System: HEK293

Osteoprotegerin Protein, Human, Recombinant (hFc)

TMPY-05262

Species: Human

Expression System: Baculovirus-Insect Cells

DDX5 Protein, Human, Recombinant (His & Myc)

TMPH-01900

Species: Human

Expression System: E. coli

FGFR2 Protein, Mouse, Recombinant (His)

TMPY-03389

Species: Mouse

Expression System: HEK293

FGFR2 Protein, Human, Recombinant (aa 1-377, His)

TMPY-01228

Species: Human

Expression System: HEK293

Osteomodulin Protein, Mouse, Recombinant (His)

TMPY-01472

Species: Mouse

Expression System: HEK293

FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)

TMPY-04390

Species: Human

Expression System: Baculovirus-Insect Cells

FGFR2 Protein, Human, Recombinant (aa 1-378, His)

TMPY-04273

Species: Human

Expression System: HEK293

FGFR2 Protein, Human, Recombinant (beta IIIc, His)

TMPY-00351

Species: Human

Expression System: HEK293

FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated

TMPY-06321

Species: Human

Expression System: HEK293

APCDD1 Protein, Human, Recombinant (hFc)

TMPY-03046

Species: Human

Expression System: HEK293

CHL2 Protein, Mouse, Recombinant (His)

TMPJ-00521

Species: Mouse

Expression System: Human Cells

--------- More ---------

Cat No.	Product Name
L7900	Osteogenesis Compound Library		320 compounds
	A unique collection of 320 osteogenesis related compounds for high throughput and high content screening;

Libraries

Osteogenesis Compound Library

L7900

Compounds: 320