omo1

JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and 3 nM for wild type and mutant Met, respectively).

6-Bromo-1,4-dihydro-2H-3,1-benzoxazin-2-one ,with CAS No. 1017783-09-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Bromo-1,4-dihydro-2H-3,1-benzoxazin-2-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Tert-Butyl5-bromo-1H-indole-1-carboxylate (N-Boc-5-bromoindole) is an indole derivative with therapeutic potential for pain, inflammation, and other conditions.

Methyl 4-bromopyrrole-2-carboxylate (4-Bromo-2-(methoxycarbonyl)-1H-pyrrole) is a marine derived natural products found in Lissodendoryx sp.

2,4,5-Tribromoimidazole (2,4,5-Tribromo-1H-imidazole) is a marine derived natural products found in Hexaplex trunculus.

1H-Indole-3-Carboxylic Acid,6-Bromo-,Methyl Ester (Methyl 6-bromo-1H-indole-3-carboxylate) is a marine derived natural products found in Smenospongia sp.

3-bromopyrrole-2,5-dione (ZINC13379821) is a marine derived natural products found in marine sponge Axinella brevistyla.

4-Bromo-1,8-naphthalic anhydride ,with CAS No. 81-86-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Bromo-1,8-naphthalic anhydride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

WEHL-04 is an intermediate used to prepare (isoquinolinylsulfonyl)benzoic acids as inhibitors of type 5 71-β-hydroxysteroid dehydrogenase AKR1C3. It is also used in the synthesis of 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists

iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.

7-Bromoquinazoline-2,4(1H,3H)-Dione (7-Bromo-2,4(1H,3H)-quinazolinedione) is a marine derived natural products found in Pyura sacciformis.

3-Bromo-1,5-naphthyridine ,with CAS No. 17965-71-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Bromo-1,5-naphthyridine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Bromo-1H-indazole ,with CAS No. 53857-58-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Bromo-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Bromo-1H-benzimidazole ,with CAS No. 4887-88-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Bromo-1H-benzimidazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Bromo-1-(2-nitrophenyl)-1H-pyrazole ,with CAS No. 957034-96-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Bromo-1-(2-nitrophenyl)-1H-pyrazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Bromo-1-fluoronaphthalene ,with CAS No. 317-79-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Bromo-1-fluoronaphthalene provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Bromo-1-(3-thienyl)-1-ethanone is a useful organic compound for research related to life sciences. The catalog number is T125824 and the CAS number is 1468-82-2.

Calcitriol Impurities D (24-Homo Calcitriol) is a hormonal form of the vitamin that promotes the differentiation of HL-60 human promyelocytic leukemia cells into monocytes.Calcitriol Impurities D has bone resorption activity and inhibits the replication of human immunodeficiency virus in human cells.Calcitriol Impurities D has antiviral activity and can be used to treat AIDS and viral infections. 25-dihydroxyvitamin D3 has antiviral activity and can be used in the treatment of AIDS and viral infections.

7-Bromo-1-heptanol is a biochemical reagent that combines the characteristics of halogenated hydrocarbons and alcohol hydroxyl groups. It can be used as a specific reaction substrate or molecular modification unit in experiments. 7-Bromo-1-heptanol is one of the practical reagents for organic synthesis and biochemical research.

Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual inhibitor targeting the PWWP domains of Hepatoma-derived Growth Factor Related Protein 2 (HDGFRP2) and its homologue PSIP1. This compound effectively hinders the occurrence and progression of Diffuse Intrinsic Pontine Glioma (DIPG). It demonstrates binding affinity with a Kd value of 7 μM for HDGFRP2, indicative of its efficient ligand efficacy at 0.47. Additionally, Compound BPP exhibits a Kd value of 27 μM when binding to the PSIP1 PWWP domain, and a Kd value of 14 μM against HDGFRP3, confirming its potency as an inhibitor within the HDGFRP2 PWWP subfamily.

4-bromo-1H-pyrazolo[3,4-b]pyridine is an important chemical intermediate used for synthesizing compounds with special activities.

8-Bromo-1-octanol is an essential esterification reagent, extensively used in the synthesis of (Z)-14-methyl-9-pentadecenoic acid and various other molecules.

4-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine is a brominated pyrrolopyridine-based scaffold designed for advanced medicinal chemistry and kinase inhibitor development. Its 7-azaindole (pyrrolopyridine) core serves as a purine bioisostere capable of occupying ATP-binding pockets across diverse kinases. The bromine substituent at the 5-position offers both electronic tuning and a versatile handle for cross-coupling reactions, enabling rapid SAR exploration. The 2-aminopyrimidine moiety further supports hinge-binding interactions, collectively making 4-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine a valuable starting point for generating FGFR-targeted inhibitors and other kinase-directed therapeutics.

4-Bromo-1-trimethylsilyl-1-butyne is a PROTAC linker utilized in the synthesis of PROTAC molecules.