omo 1

JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and 3 nM for wild type and mutant Met, respectively).

6-Bromo-1,4-dihydro-2H-3,1-benzoxazin-2-one ,with CAS No. 1017783-09-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Bromo-1,4-dihydro-2H-3,1-benzoxazin-2-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Tert-Butyl5-bromo-1H-indole-1-carboxylate (N-Boc-5-bromoindole) is an indole derivative with therapeutic potential for pain, inflammation, and other conditions.

Methyl 4-bromopyrrole-2-carboxylate (4-Bromo-2-(methoxycarbonyl)-1H-pyrrole) is a marine derived natural products found in Lissodendoryx sp.

2,4,5-Tribromoimidazole (2,4,5-Tribromo-1H-imidazole) is a marine derived natural products found in Hexaplex trunculus.

1H-Indole-3-Carboxylic Acid,6-Bromo-,Methyl Ester (Methyl 6-bromo-1H-indole-3-carboxylate) is a marine derived natural products found in Smenospongia sp.

3-bromopyrrole-2,5-dione (ZINC13379821) is a marine derived natural products found in marine sponge Axinella brevistyla.

4-Bromo-1,8-naphthalic anhydride ,with CAS No. 81-86-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Bromo-1,8-naphthalic anhydride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

WEHL-04 is an intermediate used to prepare (isoquinolinylsulfonyl)benzoic acids as inhibitors of type 5 71-β-hydroxysteroid dehydrogenase AKR1C3. It is also used in the synthesis of 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists

iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS.

7-Bromoquinazoline-2,4(1H,3H)-Dione (7-Bromo-2,4(1H,3H)-quinazolinedione) is a marine derived natural products found in Pyura sacciformis.

3-Bromo-1,5-naphthyridine ,with CAS No. 17965-71-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Bromo-1,5-naphthyridine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Bromo-1H-indazole ,with CAS No. 53857-58-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Bromo-1H-indazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Bromo-1H-benzimidazole ,with CAS No. 4887-88-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Bromo-1H-benzimidazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Bromo-1-(2-nitrophenyl)-1H-pyrazole ,with CAS No. 957034-96-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Bromo-1-(2-nitrophenyl)-1H-pyrazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Bromo-1-fluoronaphthalene ,with CAS No. 317-79-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Bromo-1-fluoronaphthalene provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Bromo-1-(3-thienyl)-1-ethanone is a useful organic compound for research related to life sciences. The catalog number is T125824 and the CAS number is 1468-82-2.

Calcitriol Impurities D (24-Homo Calcitriol) is a hormonal form of the vitamin that promotes the differentiation of HL-60 human promyelocytic leukemia cells into monocytes.Calcitriol Impurities D has bone resorption activity and inhibits the replication of human immunodeficiency virus in human cells.Calcitriol Impurities D has antiviral activity and can be used to treat AIDS and viral infections. 25-dihydroxyvitamin D3 has antiviral activity and can be used in the treatment of AIDS and viral infections.

7-Bromo-1-heptanol is a biochemical reagent that combines the characteristics of halogenated hydrocarbons and alcohol hydroxyl groups. It can be used as a specific reaction substrate or molecular modification unit in experiments. 7-Bromo-1-heptanol is one of the practical reagents for organic synthesis and biochemical research.

Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual inhibitor targeting the PWWP domains of Hepatoma-derived Growth Factor Related Protein 2 (HDGFRP2) and its homologue PSIP1. This compound effectively hinders the occurrence and progression of Diffuse Intrinsic Pontine Glioma (DIPG). It demonstrates binding affinity with a Kd value of 7 μM for HDGFRP2, indicative of its efficient ligand efficacy at 0.47. Additionally, Compound BPP exhibits a Kd value of 27 μM when binding to the PSIP1 PWWP domain, and a Kd value of 14 μM against HDGFRP3, confirming its potency as an inhibitor within the HDGFRP2 PWWP subfamily.

4-bromo-1H-pyrazolo[3,4-b]pyridine is an important chemical intermediate used for synthesizing compounds with special activities.

8-Bromo-1-octanol is an essential esterification reagent, extensively used in the synthesis of (Z)-14-methyl-9-pentadecenoic acid and various other molecules.

4-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine is a brominated pyrrolopyridine-based scaffold designed for advanced medicinal chemistry and kinase inhibitor development. Its 7-azaindole (pyrrolopyridine) core serves as a purine bioisostere capable of occupying ATP-binding pockets across diverse kinases. The bromine substituent at the 5-position offers both electronic tuning and a versatile handle for cross-coupling reactions, enabling rapid SAR exploration. The 2-aminopyrimidine moiety further supports hinge-binding interactions, collectively making 4-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine a valuable starting point for generating FGFR-targeted inhibitors and other kinase-directed therapeutics.

2-Bromo-1-decanal was synthesized as an affinity labeling probe for the aliphatic aldehyde site of Vibrio harveyi luciferase. In the presence of excess amounts of this probe, the inactivation of bacterial luciferase occurred following apparent first order