olinone

Olinone is a bromine domain inhibitor of BET protein with selectivity.

4(1H)-Quinazolinone, 5,6,7,8-tetrahydro- , with CAS No. 19178-19-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4(1H)-Quinazolinone, 5,6,7,8-tetrahydro- provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Chlorobenzothiazolinone inhibits recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay with activity value of 90 μM.

Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.

Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW) is an isothiazolinone preservative that is widely used in cosmetics to inhibit the growth of bacteria, yeasts, and fungi, while potentially causing contact skin sensitization. Methylisothiazolinone activates matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce apoptosis and inflammation.

2-Benzoxazolinone (2-Hydroxybenzoxazole) is found in cereals and cereal products. 2-Benzoxazolinone is found in rye seedlings.

4(3H)-Quinazolinone (4-Hydroxyquinazoline) is a chemically synthesized masonry block, a biologically active nitrogen heterocyclic compound. It possesses various biological properties such as antibacterial, antifungal, anticonvulsant, anti-inflammatory, anti-HIV, anticancer and pain relieving activities.

3-Methyl-2-benzothiazolinone hydrazone ,with CAS No. 1128-67-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Methyl-2-benzothiazolinone hydrazone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Morpholinone, 4-phenyl- ,with CAS No. 29518-11-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Morpholinone, 4-phenyl- provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Isoindolinone ,with CAS No. 480-91-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Isoindolinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Aminothiazolinone hydrochloride, with CAS No. 2192-06-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Aminothiazolinone hydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7-Methoxy-4(1H)-quinazolinone ,with CAS No. 16064-24-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7-Methoxy-4(1H)-quinazolinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

7,8-dihydro-5(6H)-quinolinone ,with CAS No. 53400-41-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7,8-dihydro-5(6H)-quinolinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Bromo-benzoxazolinone ,with CAS No. 19932-85-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Bromo-benzoxazolinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Nitro benzoxazolinone ,with CAS No. 4694-91-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Nitro benzoxazolinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1,2-Dihydro-3-propyl-2-thioxo-4(3H)-quinazolinone ,with CAS No. 63586-34-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1,2-Dihydro-3-propyl-2-thioxo-4(3H)-quinazolinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Amino-4(3H)-quinazolinone ,with CAS No. 14663-46-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Amino-4(3H)-quinazolinone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

[1(3H)-isoindolinone-3-yl]acetic acid ,with CAS No. 3849-22-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. [1(3H)-isoindolinone-3-yl]acetic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3,4-Dihydro-6,7-(methylenedioxy)-2(1H)-quinolinone is a useful organic compound for research related to life sciences. The catalog number is T123884 and the CAS number is 94527-34-1.

Nimolinone is presented in EENL. EENL by regulating the genes involved in cellular development and cell death functions could control cell proliferation, attenuate the stimulatory effects of VEGF, and exert antiangiogenic effects. EENL treatment could ha

In platinum-resistant A2780cis human ovarian cancer cells, thioxodihydroquinazolinone-19 is an inducer of apoptotic cell death. It acts by exhibiting a strong inhibitory effect in ovarian CSC-LCs in combination with cisplatin.

Methylisothiazolinone is a powerful synthetic biocide and preservative.

Ozolinone is an active metabolite of etozoline which acts as a loop diuretic --- a diuretic that acts at the ascending limb of the loop of Henle in the kidney. Loop diuretics are primarily used in medicine to treat hypertension and edema often due to cong

7-Hydroxy-3,4-dihydro-2(1H)-quinolinone is a weak MAO-A inhibitor(with an IC50 of 183 μM) .