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Search Results for " neurological "

Targets

274

Compounds

20

Natural Products

46

Recombinant Proteins

11

Libraries

Cat No. Product Name Synonyms Targets
T9723 GluR6 antagonist-1 Src
GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.
T23116 Oxotremorine sesquifumarate AChR
Oxotremorine sesquifumarate is a muscarinic agonist.
T15052 Dapansutrile NOD-like Receptor (NLR) , NOD
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
TP1856 Colivelin Beta Amyloid , STAT
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
T9989 AChE-IN-27 Others
AChE-IN-27 is a small molecule used for high-throughput assays.
T13320L VU591 Potassium Channel
1222810-74-3
T12421 PF-04885614 Sodium Channel
PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.
T4330 CaCCinh-A01 Chloride channel
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).
T0776 Phenothiazine ENT 38 Dopamine Receptor , Antibacterial , Antibiotic , Antifungal
Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ)...
T9694 Emraclidine CVL-231 AChR
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
T9149 2BAct 2B-Act,2B Act PERK
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response
TQ0046 Bavisant JNJ-31001074 Histamine Receptor
Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.
T13320 VU591 hydrochloride Potassium Channel
VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentr...
T8944 TTA-A2 Calcium Channel
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ...
T0082 Domperidone R33812 Dopamine Receptor
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger z...
T1476 Pramipexole SND 919 Dopamine Receptor
Pramipexole (SND 919) is a selective dopamine receptor agonist used in the therapy of Parkinson disease. Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment but has not...
T8930 CID44216842 KUC103479N-02 CDK , Ras
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT...
T4074 GSK-872 GSK872,GSK'872,GSK2399872A RIP kinase
GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
T1594 Vecuronium bromide ORG NC 45 AChR
Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity.
T6950 PNU-120596 NSC 216666 AChR
PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM.
T7805 GW791343 dihydrochloride GW791343 (HCl) P2X Receptor
GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator.
T12256 NS8593 hydrochloride NS8593 HCl Potassium Channel
NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) .
T3198L PRE-084 hydrochloride Sigma receptor
PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).
T3217 PF-CBP1 hydrochloride PF-CBP1 HCl Epigenetic Reader Domain , Histone Acetyltransferase
PF-CBP1 hydrochloride (PF-CBP1 HCl) is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively.
T4497 Amifampridine 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine Others
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...
T15247 ESI-05 NSC 116966 cAMP
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation.
T6951 Pramipexole dihydrochloride hydrate Pramipexole 2HCl Monohydrate,Mirapex Dopamine Receptor
Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and su...
T35878 N-(3-Aminopropyl)cyclohexylamine Others
N-(3-Aminopropyl)cyclohexylamine, a derivative of cyclohexylamine, functions as a selective and competitive inhibitor of spermine synthase, making it suitable for research on neurological diseases[1].
T4369 SCH-23390 hydrochloride R-(+)-SCH23390 hydrochloride Potassium Channel , Dopamine Receptor , 5-HT Receptor
SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).
T15684 L-689560 NMDAR , iGluR
L-689560 is widely used as a radiolabeled ligand in binding studies and used to study the roles of NMDA receptors in normal neurological processes as well as in diseases. At the GluN1 glycine binding site, L-689560 is an...
T6526 GW791343 trihydrochloride GW791343 3HCl P2X Receptor
GW791343 trihydrochloride (GW791343 3HCl) is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
T12865 SCH-23390 maleate R-(+)-SCH-23390 maleate Potassium Channel , Dopamine Receptor , 5-HT Receptor
SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective antagonist of dopamine D1-like receptor (1 and D5 receptor with Kis of 0.2 nM and 0.3 nM, respectively).
T68063 Elopiprazole DU 29840 Others
Elopiprazole(DU 29840) is an anti-neurological compound that can be used to study neurological disorders.
T27838 Lirequinil RO413696,RO-413696,RO41-3696,RO 413696,Ro 41-3696,Ro-41-3696 GABA Receptor
Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.
T31079 CP-810123 CP 810123,UNII-E6G4550EC4,CP810123
CP-810123 is a new alpha 7 NAChR agonist with the potential for the treatment of cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia and Alzheimer's disease.
T10056 Neurokinin antagonist 1 Neuropeptide Y Receptor
Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.
T30998L COG-1410 acetate COG-1410 acetate(878009-24-6 Free base) Apoptosis
COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.
T28258 Org-13011 fumarate Org13011,Org 13011 5-HT Receptor
Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders.
T11278 FG8119 NNC13-8119 Others
FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.
T15553 Iganidipine NKY 722 Calcium Channel
Iganidipine(NKY 722) is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.
T15655 KFM19 Adenosine Receptor
KFM19 is a potent and selective adenosine receptor (A1-receptor) antagonist (IC50 : 50 nM) for the study of neurological disorders.
T22736 DMeOB 3,3'-Dimethoxybenzaldazine GluR
DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.
T28441 PPI-1019 PPI1019,Apan Beta Amyloid
PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).
T14390 Azelaprag AMG 986 Apelin receptor
Azelaprag (AMG 986) is an effective small-molecule apelin receptor agonist. Azelaprag can be used to treat neurological diseases and cardiovascular diseases.
T22850 ICI 204,448 ICI 204448,ICI204448,ICI-204448 Opioid Receptor
ICI 204,448 is a potent κ-opioid agonist with potential analgesic activity for the study of neurological diseases.
T10732 Tematropium CDDD3602,Tematropium metilsulfate,HGP6 AChR
Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.
T11424 Glutaminyl Cyclase Inhibitor 1 Guanylate cyclase
Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.
T27572 Ibuprofen diethylaminoethyl ester Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE Others
Ibuprofen diethylaminoethyl ester (BF DEAE) has anti-inflammatory activity, acts as a local anaesthetic and can be used in the study of neurological disorders.
T22638 CBiPES hydrochloride CBiPES HCl GluR
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used ...
T14974 Citenamide Cytenamide,AY-15613 Others
Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties.

Compounds

GluR6 antagonist-1
T9723
Synonym:
Target: Src
Oxotremorine sesquifumarate
T23116
Synonym:
Target: AChR
Dapansutrile
T15052
Synonym:
Target: NOD-like Receptor (NLR), NOD
Colivelin
TP1856
Synonym:
Target: Beta Amyloid, STAT
AChE-IN-27
T9989
Synonym:
Target: Others
VU591
T13320L
Synonym:
Target: Potassium Channel
PF-04885614
T12421
Synonym:
Target: Sodium Channel
CaCCinh-A01
T4330
Synonym:
Target: Chloride channel
Phenothiazine
T0776
Synonym: ENT 38
Target: Dopamine Receptor, Antibacterial, Antibiotic, Antifungal
Emraclidine
T9694
Synonym: CVL-231
Target: AChR
2BAct
T9149
Synonym: 2B-Act,2B Act
Target: PERK
Bavisant
TQ0046
Synonym: JNJ-31001074
Target: Histamine Receptor
VU591 hydrochloride
T13320
Synonym:
Target: Potassium Channel
TTA-A2
T8944
Synonym:
Target: Calcium Channel
Domperidone
T0082
Synonym: R33812
Target: Dopamine Receptor
Pramipexole
T1476
Synonym: SND 919
Target: Dopamine Receptor
CID44216842
T8930
Synonym: KUC103479N-02
Target: CDK, Ras
GSK-872
T4074
Synonym: GSK872,GSK'872,GSK2399872A
Target: RIP kinase
Vecuronium bromide
T1594
Synonym: ORG NC 45
Target: AChR
PNU-120596
T6950
Synonym: NSC 216666
Target: AChR
GW791343 dihydrochloride
T7805
Synonym: GW791343 (HCl)
Target: P2X Receptor
NS8593 hydrochloride
T12256
Synonym: NS8593 HCl
Target: Potassium Channel
PRE-084 hydrochloride
T3198L
Synonym:
Target: Sigma receptor
PF-CBP1 hydrochloride
T3217
Synonym: PF-CBP1 HCl
Target: Epigenetic Reader Domain, Histone Acetyltransferase
Amifampridine
T4497
Synonym: 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine
Target: Others
ESI-05
T15247
Synonym: NSC 116966
Target: cAMP
Pramipexole dihydrochloride hydrate
T6951
Synonym: Pramipexole 2HCl Monohydrate,Mirapex
Target: Dopamine Receptor
N-(3-Aminopropyl)cyclohexylamine
T35878
Synonym:
Target: Others
SCH-23390 hydrochloride
T4369
Synonym: R-(+)-SCH23390 hydrochloride
Target: Potassium Channel, Dopamine Receptor, 5-HT Receptor
L-689560
T15684
Synonym:
Target: NMDAR, iGluR
GW791343 trihydrochloride
T6526
Synonym: GW791343 3HCl
Target: P2X Receptor
SCH-23390 maleate
T12865
Synonym: R-(+)-SCH-23390 maleate
Target: Potassium Channel, Dopamine Receptor, 5-HT Receptor
Elopiprazole
T68063
Synonym: DU 29840
Target: Others
Lirequinil
T27838
Synonym: RO413696,RO-413696,RO41-3696,RO 413696,Ro 41-3696,Ro-41-3696
Target: GABA Receptor
CP-810123
T31079
Synonym: CP 810123,UNII-E6G4550EC4,CP810123
Target:
Neurokinin antagonist 1
T10056
Synonym:
Target: Neuropeptide Y Receptor
COG-1410 acetate
T30998L
Synonym: COG-1410 acetate(878009-24-6 Free base)
Target: Apoptosis
Org-13011 fumarate
T28258
Synonym: Org13011,Org 13011
Target: 5-HT Receptor
FG8119
T11278
Synonym: NNC13-8119
Target: Others
Iganidipine
T15553
Synonym: NKY 722
Target: Calcium Channel
KFM19
T15655
Synonym:
Target: Adenosine Receptor
DMeOB
T22736
Synonym: 3,3'-Dimethoxybenzaldazine
Target: GluR
PPI-1019
T28441
Synonym: PPI1019,Apan
Target: Beta Amyloid
Azelaprag
T14390
Synonym: AMG 986
Target: Apelin receptor
ICI 204,448
T22850
Synonym: ICI 204448,ICI204448,ICI-204448
Target: Opioid Receptor
Tematropium
T10732
Synonym: CDDD3602,Tematropium metilsulfate,HGP6
Target: AChR
Glutaminyl Cyclase Inhibitor 1
T11424
Synonym:
Target: Guanylate cyclase
Ibuprofen diethylaminoethyl ester
T27572
Synonym: Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE
Target: Others
CBiPES hydrochloride
T22638
Synonym: CBiPES HCl
Target: GluR
Citenamide
T14974
Synonym: Cytenamide,AY-15613
Target: Others
1 2 3 4 5 6
Cat No. Product Name Synonyms Targets
T1045 Trimipramine maleate Surmontil maleate Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal...
T8392 L(+)-Asparagine monohydrate Endogenous Metabolite
L(+)-Asparagine monohydrate is a non-essential amino acid, participate in neurological and metabolic regulation of tissue cell function.
T8790 1-Methylhistamine dihydrochloride Endogenous Metabolite
1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains...
T4S1869 12-Epinapelline Others
12- Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of voltage gated Na+ channels are responsible for these obser...
TQ0295 Coumestrol Estrogen Receptor/ERR
Coumestrol that existed in soybean products suppresses the proliferation of ES2 cells (IC50: 50 μM). It exhibits activities against neurological disorders, cancers and autoimmune diseases.
T5076 L-Allothreonine L-allo-Threonine Others , Endogenous Metabolite
L-Allothreonine (L-allo-Threonine) is an essential amino acid in humans. L-Allothreonine is abundant in human plasma, particularly in newborns. Severe deficiency of threonine causes neurological dysfunction and lameness ...
T4887 3-Amino-2-methylpropanoic acid DL-3-AMINOISOBUTYRIC ACID,α-Methyl-β-alanine Endogenous Metabolite
3-Amino-2-methylpropanoic acid (α-Methyl-β-alanine) is the product from the conversion of N-carbamyl-beta-aminoisobutyric acid by the enzyme Beta-ureidopropionase (EC 3.5.1.6), the last step in pyrimidine degradation. Be...
T66582 6-Methylnicotinamide Endogenous Metabolite
6-Methylnicotinamide is a derivative of nicotinamide, an endogenous metabolite. 6-Methylnicotinamide is used to make co-crystals/salts. In the acute phase of cerebral hemorrhage (ICH), a sudden increase in 6-Methylnicoti...
T32614 L-Clausenamide (-)-Clausenamide Microtubule Associated
L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents t...
T7984 2-Hydroxyflavanone Others
2-Hydroxyflavanone is a naturally occurring flavonoid found in many plants and fruits. It has antioxidant, anti-inflammatory and anti-tumor activity, scavenging free radicals, reducing inflammation and inhibiting the gro...
T3578 Pyridoxal phosphate PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate Reverse Transcriptase , Endogenous Metabolite
Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and d...
TN4368 Kaempferol-3,7-di-O-β-glucoside Kaempferol 3,7-di-O-glucoside Glucosidase , Amylase
Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective ac...
T3011 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine Others , Endogenous Metabolite
2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid (3-Anthraniloylalanine) is a ketone and an amino acid derivative with diverse biological functions, including vasodilatory, immunoregulatory and neuromodulatory activities. 2-...
T4S2126 Ginkgetin Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...
TN2299 Vindesine Others
Vindesine is a microtubule inhibitor and widely used to treat malignancies. Vindesine neuropathy seems to be the cause of the patient's neurological symptoms.
T82341 Ganglioside GM1
Ganglioside GM1, a member of the ganglioside family, serves as a functional tissue receptor for Cholera Toxin1 [1] and is utilized in neurological disease research.
T37177 Norcholic Acid
Norcholic acid is a bile acid and 23-carbon derivative of cholic acid .1Levels of norcholic acid are increased in the urine of patients with liver cirrhosis or cerebrotendinous xanthomatosis (CTX), an inborn error of met...
T75700 Longistyline A
Longistyline A (Longistylin A), a natural stilbene extracted from the leaves of Cajanus cajan, exhibits antimicrobial activity with a minimum inhibitory concentration (MIC) value of 1.56 μg/mL against MRSA and demonstrat...
T16165 Myriocin ISP-I,Thermozymocidin HCV Protease , Antifungal
Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticancer, and antiparasitic activities.Myriocin inhibits tumour g...
TN3364 Agrimonolide Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK
Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts anti-inflammatory effects by inhibiting lipopolysaccharide ...

Natural Products

Trimipramine maleate
T1045
Synonym: Surmontil maleate
Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Norepinephrine, Histamine Receptor
L(+)-Asparagine monohydrate
T8392
Synonym:
Target: Endogenous Metabolite
1-Methylhistamine dihydrochloride
T8790
Synonym:
Target: Endogenous Metabolite
12-Epinapelline
T4S1869
Synonym:
Target: Others
Coumestrol
TQ0295
Synonym:
Target: Estrogen Receptor/ERR
L-Allothreonine
T5076
Synonym: L-allo-Threonine
Target: Others, Endogenous Metabolite
3-Amino-2-methylpropanoic acid
T4887
Synonym: DL-3-AMINOISOBUTYRIC ACID,α-Methyl-β-alanine
Target: Endogenous Metabolite
6-Methylnicotinamide
T66582
Synonym:
Target: Endogenous Metabolite
L-Clausenamide
T32614
Synonym: (-)-Clausenamide
Target: Microtubule Associated
2-Hydroxyflavanone
T7984
Synonym:
Target: Others
Pyridoxal phosphate
T3578
Synonym: PLP,PAL-P,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate
Target: Reverse Transcriptase, Endogenous Metabolite
Kaempferol-3,7-di-O-β-glucoside
TN4368
Synonym: Kaempferol 3,7-di-O-glucoside
Target: Glucosidase, Amylase
2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
T3011
Synonym: Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine
Target: Others, Endogenous Metabolite
Ginkgetin
T4S2126
Synonym:
Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy
Vindesine
TN2299
Synonym:
Target: Others
Ganglioside GM1
T82341
Synonym:
Target:
Norcholic Acid
T37177
Synonym:
Target:
Longistyline A
T75700
Synonym:
Target:
Myriocin
T16165
Synonym: ISP-I,Thermozymocidin
Target: HCV Protease, Antifungal
Agrimonolide
TN3364
Synonym:
Target: Apoptosis, Dehydrogenase, p38 MAPK, ROS, JAK

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02284 HN1 Protein, Mouse, Recombinant (His) Mouse E. coli
TMPY-01003 TCN2 Protein, Human, Recombinant (His) Human HEK293
Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin...
TMPY-01431 L1CAM Protein, Human, Recombinant (His) Human HEK293
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-02785 Tetranectin Protein, Mouse, Recombinant (His) Mouse HEK293
Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes v...
TMPY-00735 Cathepsin S Protein, Human, Recombinant (His) Human HEK293
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS...
TMPY-02751 Cathepsin S Protein, Mouse, Recombinant (His) Mouse HEK293
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS...
TMPY-05053 ANGPTL2 Protein, Human, Recombinant (His) Human HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-06802 HSV 2 (strain 333) Glycoprotein D/gD Protein (His) HSV2 HEK293
Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. Herpes simplex virus type 2 (HSV-2) infection is responsible for signific...
TMPK-01049 CLEC7A Protein, Mouse, Recombinant (hFc) Mouse HEK293
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis...
TMPK-00699 FAM19A5 Protein, Human, Recombinant (His) Human E. coli
FAM19A5 is a secretory protein that is predominantly expressed in the brain. Although the FAM19A5 gene has been found to be associated with neurological and/or psychiatric diseases, only limited information is available ...
TMPK-01125 FAM19A5 Protein, Mouse, Recombinant (His) Mouse E. coli
FAM19A5 is a secretory protein that is predominantly expressed in the brain. Although the FAM19A5 gene has been found to be associated with neurological and/or psychiatric diseases, only limited information is available ...
TMPJ-01002 SGSH Protein, Human, Recombinant (His) Human Human Cells
N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-su...
TMPK-00817 Glycophorin A Protein, Mouse, Recombinant (hFc) Mouse HEK293
Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes...
TMPK-00534 Glycophorin A Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes...
TMPK-00818 Glycophorin A Protein, Mouse, Recombinant (His) Mouse HEK293
Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes...
TMPK-00029 Glycophorin A Protein, Human, Recombinant (hFc) Human HEK293
Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes...
TMPK-01216 SEMA7A Protein, Mouse, Recombinant (His) Mouse HEK293
Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic ra...
TMPJ-01022 SUMO3 Protein, Human, Recombinant (HEK293, His) Human Human Cells
Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way...
TMPY-03852 Dopamine beta-Hydroxylase Protein, Human, Recombinant (His) Human HEK293
DBH is a 29 kDa copper-containing oxygenase. It can be detected in noradrenergic nerve terminals of the central and peripheral nervous systems, and is also expressed in chromaffin cells of the adrenal medulla. DBH conta...
TMPJ-00295 NgR Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a recept...
TMPY-03332 PRTFDC1 Protein, Human, Recombinant (His) Human E. coli
PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG ...
TMPK-00741 SEMA7A Protein, Human, Recombinant (His) Human HEK293
Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic ra...
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc) Human HEK293
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPY-04300 NRG3 Protein, Human, Recombinant (His) Human HEK293
NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influe...
TMPY-00192 NRG3 Protein, Human, Recombinant (hFc) Human HEK293
NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influe...
TMPY-02192 TCN2 Protein, Mouse, Recombinant (His) Mouse HEK293
Transcobalamin II, also known as TCN2 and TC II, is a plasma protein that binds cobalamin (Cbl; vitamin B12) as it is absorbed in the terminal ileum and distributes to tissues. The circulating transcobalamin II-cobalamin...
TMPY-03452 PTS Protein, Human, Recombinant (His) Human E. coli
PTS(6-pyruvoyltetrahydropterin synthase) belongs to the PTPS family. It catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesi...
TMPY-06759 L1CAM Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-06857 L1CAM Protein, Human, Recombinant (hFc) Human HEK293
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-02140 Tetranectin Protein, Human, Recombinant (His) Human HEK293
Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes v...
TMPY-06796 L1CAM Protein, Mouse, Recombinant (hFc) Mouse HEK293
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai...
TMPY-01056 Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc) Human HEK293
Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le...
TMPY-01221 Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le...
TMPY-03144 Nogo Receptor/RTN4R Protein, Human, Recombinant (His) Human HEK293
Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le...
TMPY-01163 Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His) Mouse HEK293
Reticulon 4 receptor (RTN4R), also known as Nogo-66 Receptor (NgR), is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family including three members. Mouse RTN4R cDNA contains 1 LRP (Le...
TMPY-02025 CPLX2 Protein, Human, Recombinant (His) Human E. coli
Complexin-2 (CPLX2), a member of the complexin/synaphin family, is a soluble pre-synaptic protein believed to regulate neurotransmitter release from pre-synaptic terminals. Complexins are soluble proteins that regulate t...
TMPY-02027 BID Protein, Human, Recombinant Human E. coli
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro...
TMPJ-00495 ISG15 Protein, Human, Recombinant (His) Human E. coli
Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta. Several functions have been ascribed to the encoded protei...
TMPY-02065 BID Protein, Mouse, Recombinant (His & GST) Mouse E. coli
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro...
TMPY-00670 ARSA Protein, Mouse, Recombinant (His) Mouse HEK293
Arylsulfatase A (ARSA) is synthesized as a 52KDa lysosomal enzyme. It is a member of the sulfatase family that is required for the lysosomal degradation of cerebroside-3-sulfate, a sphingolipid sulfate ester and a major ...
TMPY-03579 CNTN5 Protein, Mouse, Recombinant (His) Mouse HEK293
Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed mainly in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1...
TMPY-00669 ARSA Protein, Human, Recombinant (His) Human HEK293
Arylsulfatase A (ARSA) is synthesized as a 52KDa lysosomal enzyme. It is a member of the sulfatase family that is required for the lysosomal degradation of cerebroside-3-sulfate, a sphingolipid sulfate ester and a major ...
TMPY-00724 CNTN5 Protein, Human, Recombinant (His) Human HEK293
Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed mainly in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1...
TMPY-01290 CHIT1 Protein, Human, Recombinant (His) Human HEK293
Chitotriosidase, also known as Chitinase-1 and CHIT1, is a member of the glycosyl hydrolase 18 family and Chitinase class II subfamily. It is a member of the mammalian chitinase family, structurally homologous to chitina...
TMPY-00362 Cathepsin S Protein, Rat, Recombinant (His) Rat HEK293
Cathepsin S (CTSS), one of the lysosomal proteinases, has many important physiological functions in the nervous system, especially in process of extracellular matrix degradation and endocellular antigen presentation. CTS...
TMPY-03998 ANGPTL2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
HN1 Protein, Mouse, Recombinant (His)
TMPY-02284
Species: Mouse
Expression System: E. coli
TCN2 Protein, Human, Recombinant (His)
TMPY-01003
Species: Human
Expression System: HEK293
L1CAM Protein, Human, Recombinant (His)
TMPY-01431
Species: Human
Expression System: HEK293
Tetranectin Protein, Mouse, Recombinant (His)
TMPY-02785
Species: Mouse
Expression System: HEK293
Cathepsin S Protein, Human, Recombinant (His)
TMPY-00735
Species: Human
Expression System: HEK293
Cathepsin S Protein, Mouse, Recombinant (His)
TMPY-02751
Species: Mouse
Expression System: HEK293
ANGPTL2 Protein, Human, Recombinant (His)
TMPY-05053
Species: Human
Expression System: HEK293
HSV 2 (strain 333) Glycoprotein D/gD Protein (His)
TMPY-06802
Species: HSV2
Expression System: HEK293
CLEC7A Protein, Mouse, Recombinant (hFc)
TMPK-01049
Species: Mouse
Expression System: HEK293
FAM19A5 Protein, Human, Recombinant (His)
TMPK-00699
Species: Human
Expression System: E. coli
FAM19A5 Protein, Mouse, Recombinant (His)
TMPK-01125
Species: Mouse
Expression System: E. coli
SGSH Protein, Human, Recombinant (His)
TMPJ-01002
Species: Human
Expression System: Human Cells
Glycophorin A Protein, Mouse, Recombinant (hFc)
TMPK-00817
Species: Mouse
Expression System: HEK293
Glycophorin A Protein, Cynomolgus, Recombinant (His)
TMPK-00534
Species: Cynomolgus
Expression System: HEK293
Glycophorin A Protein, Mouse, Recombinant (His)
TMPK-00818
Species: Mouse
Expression System: HEK293
Glycophorin A Protein, Human, Recombinant (hFc)
TMPK-00029
Species: Human
Expression System: HEK293
SEMA7A Protein, Mouse, Recombinant (His)
TMPK-01216
Species: Mouse
Expression System: HEK293
SUMO3 Protein, Human, Recombinant (HEK293, His)
TMPJ-01022
Species: Human
Expression System: Human Cells
Dopamine beta-Hydroxylase Protein, Human, Recombinant (His)
TMPY-03852
Species: Human
Expression System: HEK293
NgR Protein, Mouse, Recombinant (hFc)
TMPJ-00295
Species: Mouse
Expression System: Human Cells
PRTFDC1 Protein, Human, Recombinant (His)
TMPY-03332
Species: Human
Expression System: E. coli
SEMA7A Protein, Human, Recombinant (His)
TMPK-00741
Species: Human
Expression System: HEK293
SUSD4 Protein, Human, Recombinant (mFc)
TMPY-03969
Species: Human
Expression System: HEK293
NRG3 Protein, Human, Recombinant (His)
TMPY-04300
Species: Human
Expression System: HEK293
NRG3 Protein, Human, Recombinant (hFc)
TMPY-00192
Species: Human
Expression System: HEK293
TCN2 Protein, Mouse, Recombinant (His)
TMPY-02192
Species: Mouse
Expression System: HEK293
PTS Protein, Human, Recombinant (His)
TMPY-03452
Species: Human
Expression System: E. coli
L1CAM Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06759
Species: Human
Expression System: HEK293
L1CAM Protein, Human, Recombinant (hFc)
TMPY-06857
Species: Human
Expression System: HEK293
Tetranectin Protein, Human, Recombinant (His)
TMPY-02140
Species: Human
Expression System: HEK293
L1CAM Protein, Mouse, Recombinant (hFc)
TMPY-06796
Species: Mouse
Expression System: HEK293
Nogo Receptor/RTN4R Protein, Human, Recombinant (His & hFc)
TMPY-01056
Species: Human
Expression System: HEK293
Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His & hFc)
TMPY-01221
Species: Mouse
Expression System: HEK293
Nogo Receptor/RTN4R Protein, Human, Recombinant (His)
TMPY-03144
Species: Human
Expression System: HEK293
Nogo Receptor/RTN4R Protein, Mouse, Recombinant (His)
TMPY-01163
Species: Mouse
Expression System: HEK293
CPLX2 Protein, Human, Recombinant (His)
TMPY-02025
Species: Human
Expression System: E. coli
BID Protein, Human, Recombinant
TMPY-02027
Species: Human
Expression System: E. coli
ISG15 Protein, Human, Recombinant (His)
TMPJ-00495
Species: Human
Expression System: E. coli
BID Protein, Mouse, Recombinant (His & GST)
TMPY-02065
Species: Mouse
Expression System: E. coli
ARSA Protein, Mouse, Recombinant (His)
TMPY-00670
Species: Mouse
Expression System: HEK293
CNTN5 Protein, Mouse, Recombinant (His)
TMPY-03579
Species: Mouse
Expression System: HEK293
ARSA Protein, Human, Recombinant (His)
TMPY-00669
Species: Human
Expression System: HEK293
CNTN5 Protein, Human, Recombinant (His)
TMPY-00724
Species: Human
Expression System: HEK293
CHIT1 Protein, Human, Recombinant (His)
TMPY-01290
Species: Human
Expression System: HEK293
Cathepsin S Protein, Rat, Recombinant (His)
TMPY-00362
Species: Rat
Expression System: HEK293
ANGPTL2 Protein, Mouse, Recombinant (hFc)
TMPY-03998
Species: Mouse
Expression System: HEK293
Cat No. Product Name
L7400 Sodium Channel Blocker Library

128 compounds
A unique collection of 128 sodium channel blockers and agonists for high throughput and high content screening;
L2800 Serotonin Receptor-Targeted Compound Library

275 compounds
A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening;
L2600 Neuronal Signaling Compound Library

2540 compounds
A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L4660 Anti-Nervous System Disease Library

1246 compounds
Well-chosen 1246 compounds with unique structures targeting nervous system;
L1610 FDA-Approved Kinase Inhibitor Library

266 compounds
A unique collection of 266 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L7700 Neural Regeneration Compound Library

529 compounds
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;
L3300 Histamine & Melatonin Receptor-Targeted Compound Library

155 compounds
A unique collection of 155 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L2630 Neuronal Differentiation Compound Library

680 compounds
680 compounds related to neuronal differentiation, suitable for the drug development of nervous system disease.
L8720 Pyroptosis Compound Library

1077 compounds
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L2610 Neurotransmitter Receptor Compound Library

1513 compounds
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;
L9840 Anti-Alzheimer's Disease Compound Library

1040 compounds
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
TargetMol