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Search Results for " necrosis "

Targets

137

Compounds

57

Natural Products

421

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T39849 Propargite Parasite
Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC 50 of 1 μM [1] .
T4319 Hispidol (Z)-Hispidol TNF
Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.
T6904 Necrosulfonamide (E)-Necrosulfonamide MLK
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during nec...
T14848 C 87 Others , TNF
C 87 is a small-molecule TNF-α inhibitor. C 87 directly binds to TNFα, potently inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 μM), and effectively blocks TNF-α-triggered signaling activities.
T11991 Mefentrifluconazole P450 , Antifungal
Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and ...
T11096 DRI-C21045 NF-κB
Dri-c21045 showed concentration-dependent inhibition of NF- B activation and all CD40L induced by B cell proliferation. IC50 was 17.1 M and 4.5 M, respectively.Dri-c21045 is an effective selective inhibitor of CD40-CD40L...
T9921 Infliximab TNF
Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.
T2065 Bioymifi DR5 Activator Apoptosis , TNF
Bioymifi (DR5 Activator) is a novel and potent small-molecule activator of the TRAIL receptor DR5 in human cancer cells.
T13951 UCB-9260 TNF
UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.
T12997 SR-318 p38 MAPK , TNF
SR-318 is a potent and highly selective inhibitor of p38 MAPK(IC50s of 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively), has anti-cancer and anti-inflammatory activity.
T7001 TIC10 ONC-201 Apoptosis , TNF
TIC10 (ONC-201) inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.
T6649 (S)-(+)-Rolipram (S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram Apoptosis , PDE
(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
T8692 (Rac)-Benpyrine TNF
(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.
T8616 Fasentin N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide transporter
Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.
T3561 CPI1189 CPI-1189,REN-1189,CPI 1189 TNF
CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
T7091 N-Formyl-Met-Leu-Phe fMLP,N-Formyl-MLF TNF
N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).
T4423 LY 303511 hydrochloride LY303511 hydrochloride Potassium Channel , TNF , mTOR
LY 303511 hydrochloride is a potent mTOR inhibitor
T1813 VGX-1027 VGX1027,VGX 1027,GIT 27 IL Receptor , TNF , Interleukin
VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.
T6204 QNZ CAY10470,EVP4593 TNF , NF-κB
QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.
T4637 R-7050 TNF-α Antagonist III TNF
R-7050 (TNF-α Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
T22051 BU 224 hydrochloride Imidazoline Receptor
BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
T14975 CJ-42794 CJ-042794 Others
CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-...
T7889 C25-140 Others , TNF , E1/E2/E3 Enzyme , NF-κB
C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.
T4403 AX-024 hydrochloride AX-024 HCl IL Receptor , TNF , COX , IFNAR , Interleukin
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
T8845 UTL-5g 3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-,GBL-5g TNF
UTL-5g (3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-) is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hemat...
T2923 Apremilast CC-10004 Apoptosis , TNF , PDE
Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities.
T60012 HS-243 IRAK , MAPK , CDK
HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
T4412 Roquinimex Linomide,LS2616,FCF89,ABR212616 TNF
Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.
T6085 PF-543 Sphingosine Kinase 1 Inhibitor II,PF 543 Apoptosis , S1P Receptor , Autophagy , LPL Receptor
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
T0446 Naphazoline hydrochloride Albalon,Rhinantin,Naphazoline HCl Adrenergic Receptor
Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.
T21445 Naphazoline AK-Con,Naphcon-a,Clear Eyes,All Clear Adrenergic Receptor
Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity. Naphazoline can be used as a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane.
T8840 PF-543 hydrochloride PF-543 Apoptosis , S1P Receptor , Autophagy , LPL Receptor
PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
TQ0181 Resatorvid CLI-095,TAK-242 TNF , TLR , Autophagy , Interleukin
Resatorvid (TAK-242) (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 nM).
T70061 CGP 71683 (free base)
CGP 71683 (free base) is a potent and highly selective non-peptide antagonist of the NPY Y(5) receptor in the study of obesity.
T1083L Theophylline monohydrate Quibron HDAC , PDE , Adenosine Receptor
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ...
T0304 Methylthiouracil NSC-193526,NSC-9378,MTU ERK , Antiviral , TNF , NF-κB , Interleukin
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
T12985L SPD304 TNF
SPD304 is a selective TNF-α inhibitor and blocks the interaction of TNF and its receptor. SPD304 has an IC50 of 22 µM for inhibiting in vitro TNF receptor 1 binding to TNF-α.
T2434 LY 303511 Potassium Channel , TNF , mTOR
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for PI3-K.
T9537 N'-Nitro-D-arginine N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid Others
N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.
T11484 GSK2593074A GSK'074 TNF , RIP kinase
GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.
T24160 IM-54 IM 54,IM54 MLK
IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.
T41027 MLKL-IN-2 MLK
MLKL-IN-2 is an MLKL inhibitor with potential tumorigenic activity for the study of cellular necrosis-related diseases.
T23480 U-83836E Others
U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock.
T19584L TNF-α (31-45), human acetate TNF-α (31-45), human acetate(144796-71-4 free base) Others
TNF-α (31-45), human acetate is a peptide of tumor necrosis factor-α.
T6273 Vadimezan DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404 Influenza Virus , VDA , STING , IFNAR
Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan(NSC 640488) induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide...
T35367 Thioacetamide TAA Others
Thioacetamide is a hepatotoxicant used widely to induce experimental liver lesions, develops hepatocellular necrosis and subsequent inflammation (mainly M1-/M2-macrophages without neutrophil infiltration) in rats.
T8400 Pamidronic acid Wnt/beta-catenin
Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells
T28607 Rocepafant LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730 Platelet aggregation
Rocepafant (LAU8080) is a platelet-activating factor (PAF) antagonist that attenuates hypoxic-ischemic brain damage in neonatal rats.Rocepafant inhibits tumor necrosis factor-Afa-mediated cytotoxicity in mouse L929 tumor...
T17192 Ubiquitin Isopeptidase Inhibitor I, G5 NSC144303 Apoptosis
Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively).
T22330 Fenamic acid 2-Anilinobenzoic acid,Diphenylamine-2-carboxylic acid,2-(Phenylamino)benzoic acid,N-Phenylanthranilic acid Chloride channel
Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats. Fenamic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), inc...

Compounds

Propargite
T39849
Synonym:
Target: Parasite
Hispidol
T4319
Synonym: (Z)-Hispidol
Target: TNF
Necrosulfonamide
T6904
Synonym: (E)-Necrosulfonamide
Target: MLK
C 87
T14848
Synonym:
Target: Others, TNF
Mefentrifluconazole
T11991
Synonym:
Target: P450, Antifungal
DRI-C21045
T11096
Synonym:
Target: NF-κB
Infliximab
T9921
Synonym:
Target: TNF
Bioymifi
T2065
Synonym: DR5 Activator
Target: Apoptosis, TNF
UCB-9260
T13951
Synonym:
Target: TNF
SR-318
T12997
Synonym:
Target: p38 MAPK, TNF
TIC10
T7001
Synonym: ONC-201
Target: Apoptosis, TNF
(S)-(+)-Rolipram
T6649
Synonym: (S)-Rolipram,(+)-Rolipram,S- (+)-Rolipram
Target: Apoptosis, PDE
(Rac)-Benpyrine
T8692
Synonym:
Target: TNF
Fasentin
T8616
Synonym: N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
Target: transporter
CPI1189
T3561
Synonym: CPI-1189,REN-1189,CPI 1189
Target: TNF
N-Formyl-Met-Leu-Phe
T7091
Synonym: fMLP,N-Formyl-MLF
Target: TNF
LY 303511 hydrochloride
T4423
Synonym: LY303511 hydrochloride
Target: Potassium Channel, TNF, mTOR
VGX-1027
T1813
Synonym: VGX1027,VGX 1027,GIT 27
Target: IL Receptor, TNF, Interleukin
QNZ
T6204
Synonym: CAY10470,EVP4593
Target: TNF, NF-κB
R-7050
T4637
Synonym: TNF-α Antagonist III
Target: TNF
BU 224 hydrochloride
T22051
Synonym:
Target: Imidazoline Receptor
CJ-42794
T14975
Synonym: CJ-042794
Target: Others
C25-140
T7889
Synonym:
Target: Others, TNF, E1/E2/E3 Enzyme, NF-κB
AX-024 hydrochloride
T4403
Synonym: AX-024 HCl
Target: IL Receptor, TNF, COX, IFNAR, Interleukin
UTL-5g
T8845
Synonym: 3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-,GBL-5g
Target: TNF
Apremilast
T2923
Synonym: CC-10004
Target: Apoptosis, TNF, PDE
HS-243
T60012
Synonym:
Target: IRAK, MAPK, CDK
Roquinimex
T4412
Synonym: Linomide,LS2616,FCF89,ABR212616
Target: TNF
PF-543
T6085
Synonym: Sphingosine Kinase 1 Inhibitor II,PF 543
Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor
Naphazoline hydrochloride
T0446
Synonym: Albalon,Rhinantin,Naphazoline HCl
Target: Adrenergic Receptor
Naphazoline
T21445
Synonym: AK-Con,Naphcon-a,Clear Eyes,All Clear
Target: Adrenergic Receptor
PF-543 hydrochloride
T8840
Synonym: PF-543
Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor
Resatorvid
TQ0181
Synonym: CLI-095,TAK-242
Target: TNF, TLR, Autophagy, Interleukin
CGP 71683 (free base)
T70061
Synonym:
Target:
Theophylline monohydrate
T1083L
Synonym: Quibron
Target: HDAC, PDE, Adenosine Receptor
Methylthiouracil
T0304
Synonym: NSC-193526,NSC-9378,MTU
Target: ERK, Antiviral, TNF, NF-κB, Interleukin
SPD304
T12985L
Synonym:
Target: TNF
LY 303511
T2434
Synonym:
Target: Potassium Channel, TNF, mTOR
N'-Nitro-D-arginine
T9537
Synonym: N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid
Target: Others
GSK2593074A
T11484
Synonym: GSK'074
Target: TNF, RIP kinase
IM-54
T24160
Synonym: IM 54,IM54
Target: MLK
MLKL-IN-2
T41027
Synonym:
Target: MLK
U-83836E
T23480
Synonym:
Target: Others
TNF-α (31-45), human acetate
T19584L
Synonym: TNF-α (31-45), human acetate(144796-71-4 free base)
Target: Others
Vadimezan
T6273
Synonym: DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404
Target: Influenza Virus, VDA, STING, IFNAR
Thioacetamide
T35367
Synonym: TAA
Target: Others
Pamidronic acid
T8400
Synonym:
Target: Wnt/beta-catenin
Rocepafant
T28607
Synonym: LAU 8080,LAU8080,BN 50730,LAU-8080,BN50730,BN-50730
Target: Platelet aggregation
Ubiquitin Isopeptidase Inhibitor I, G5
T17192
Synonym: NSC144303
Target: Apoptosis
Fenamic acid
T22330
Synonym: 2-Anilinobenzoic acid,Diphenylamine-2-carboxylic acid,2-(Phenylamino)benzoic acid,N-Phenylanthranilic acid
Target: Chloride channel
1 2 3
Cat No. Product Name Synonyms Targets
T6S2099 Geraniin Antioxidant , TNF
1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Geraniin exerts inhibitory effects on osteoclast differentiation ...
T6S0630 Hypaconitine P450 , TNF
Hypaconitine, an active and highly toxic constituent derived from Aconitum species, has anti-inflammatory activity, is widely used to treat rheumatism.
T4S0217 HOMOPLANTAGININ TNF , NF-κB
Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia,it has a protective and therapeutic effect on hepatocyte injury and shows potent inhibitory activities against influenza.
T6S1597 Mulberroside A TNF , Tyrosinase , Interleukin
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...
T6S0627 Mesaconitine TNF
1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system.
T2879 Fisetin TNF , Sirtuin , PPAR
Fisetin is a natural flavonol extracted from Rhus succedanea L that is structurally and functionally related to kaempferol, can modulate sirtuins,with antioxidant, anticancer, neuroprotection effects.
T3893 Forsythoside B TNF , NF-κB
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...
T4S0227 Sinensetin Pedalitin permethyl ether TNF , PGE Synthase
Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.
T4S1521 1,4-Dicaffeoylquinic acid HIV Protease
1,4-Dicaffeoylquinic acid has antioxidant activity.1,4-Dicaffeoylquinic acid is a potent and highly selective class of HIV-1 integrase inhibitors, inhibitsHIV-1 replication in MT-2 cell culture at non-toxic concentration...
T2720 Ginsenoside Rc Panaxoside Rc Others , TNF , GABA Receptor , Interleukin
Ginsenoside Rc (Panaxoside Rc) is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.
T7786 Tryptanthrin DNA gyrase
Tryptanthrin is a natural DNA gyrase inhibitor.
TN6796 2'-FUCOSYLLACTOSE 2'-Fucosyl-D-lactose Others
2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) is a fucose-containing oligosaccharide.
T2S0843 Negletein 7-O-Methylbaicalein,Baicalein-7-methylether IL Receptor , TNF , NOS , Interleukin
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...
T2893 Muscone 3-Methylcyclopentadecanone,Methylexaltone MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T2758 Madecassic acid 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose Others , TNF , COX , NO Synthase , Interleukin
Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.
T2794 Astilbin Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,Neoisoastilbin TNF , NF-κB , Nrf2
Astilbin (Neoastilbin) is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.
T6S1538 Neochlorogenic acid trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid TNF , NF-κB , COX , Antibacterial , Interleukin
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
TN1291 7,3',4'-Tri-O-methylluteolin 5-Hydroxy-3',4',7-trimethoxyflavone TNF , COX , Interleukin
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC value of 19.0 ug/ml
T1125 Shikonin NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid TNF , NF-κB , Chloride channel , HIV Protease , PKM
Shikonin (Anchusa acid) is an TMEM16A chloride channel inhibitor (IC50: 6.5 μM). Shikonin is also a selective PKM2 inhibitor and can also suppress activation of the NF-κB pathway and inhibit TNF-α. Shikonin decreases exo...
T2932 Ginsenoside Rh1 Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1 IL Receptor , TNF , Endogenous Metabolite , PPAR , Interleukin
Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T6S2140 β-Anhydroicaritin Anhydroicaritin,Beta-Anhydroicaritin MMP , Others , TNF , Interleukin
1. β-Anhydroicaritin exhibits immunosuppressive effect on the mouse macrophages stimulated by LPS. 2. β-Anhydroicaritin phytosomes can inhibit enhanced bone turnover induced by ovariectomy, improve BMD the biomechanical ...
TWA2417 Sodium taurocholate Taurocholate Sodium Others
Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and...
T8704 4-hydroxyphenyl acetate Nrf2
4-Acetoxyphenol Prevents RPE Oxidative Stress-Induced Necrosis by Functioning as an NRF2 Stabilizer
PDK0060 Pseudotropine Others
Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.
T41288 Myristoleic acid cis-9-tetradecenoic acid,9-Tetradecenoic acid,(Z)-Tetradec-9-enoic acid Apoptosis
Myristoleic acid (9-Tetradecenoic acid) is a cytotoxic component in the extract from Serenoa repens. Myristoleic acid induces apoptosis and necrosis in human prostatic LNCaP cells.
TN1163 2'-Hydroxychalcone Others
2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc...
TN2108 Protohypericin Others
Protohypericin is a naturally occurring naphthodianthrone derived from plant Hypericum perforatum.Radioiodinated protohypericin is used in Tumor necrosis targeted radiotherapy. Protohypericin exhibits photocytotoxicity.
T8852 Tubuloside B Apoptosis , Others
The neuroprotective effect of tubuloside B, one of the phenylethanoids isolated from the stems of Cistanche salsa, on tumor necrosis factor-alpha (TNFalpha)-induced apoptosis in SH-SY5Y neuronal cells.
TN2259 Taurocholic acid N-Choloyltaurine TNF , PI3K
Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathwa...
T2731 Usnic Acid Usniacin Antibacterial , Autophagy
Usnic Acid (Usniacin) is an antimicrobial, antitumor and enzyme inhibiting agent shown to uncouple oxidative phosphorylation in mouse-liver mitochondria. Usnic acid induces necrosis in certain cells.
T5660 Menthone IL Receptor , TNF , NF-κB , Parasite
Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha),as well as nuclear factor k...
T0131 Cepharanthine NSC-623442 Apoptosis , TNF , HIV Protease , Autophagy
Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.
T3674 Hydroxysafflor yellow A HSYA,Safflomin A TGF-beta/Smad
Hydroxysafflor yellow A (Safflomin A) inhibited adipogenesis by increasing HSL promoter activities. Hydroxysafflor yellow A can effectively protect the liver from long-term alcohol injury by enhancing antioxidant capacit...
T3S0057 Dihydrochelerythrine 12,13-Dihydrochelerythrine Antifungal
1. Dihydrochelerythrine (12,13-Dihydrochelerythrine) is nontoxic up to 5μM concentration. 2. Dihydrochelerythrine has antifungal activity against pathogenic plant fungi. 3. Dihydrochelerythrine has potential application ...
T0186 Docetaxel trihydrate RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate Apoptosis , BCL , Microtubule Associated
Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the therapy of many solid tumor i...
T75636 (E/Z)-Squalene (E/Z)-Super Squalene,(E/Z)-AddaVax
(E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production and induces apoptosis and necrosis in a concentration and time-dependent manner. (E/Z)-Squalene is a triterpenoid compound ...
TN3049 4-Methoxycinnamyl alcohol Others
4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively. 4-Methoxycinnamyl alcohol was isolated from Foeniculum vulgare. 4-Methox...
T3864 Erianin BCL , Antibacterial
Erianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity , can cause extensive tumour necrosis, growth delay. Erianin has antiangiogenic action by inhibiting endothelial metaboli...
T6S1256 Ruscogenin NOS , NF-κB , NOD-like Receptor (NLR)
1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ...
T6S1579 Monotropein Monotropeine Others
1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf...
T2823 Crocin Gardenia Yellow,Alpha-Crocin Others
Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne...
T2S2264 Linalool Linalol,(±)-Linalool,Phantol Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T5089 5-Aminovaleric acid Others , Endogenous Metabolite
5-aminovalerate (or 5-aminopentanoic acid) is a lysine degradation product. It can be produced both endogenously or through bacterial catabolism of lysine. 5-aminovalerate is formed via the following multi-step reaction:...
TN4409 Lansiumarin C TNF
Lansiumarin C can decrease nitric oxide (NO) and tumor necrosis factor-α (TNF-α) production in lipopolysaccharide (LPS)-induced macrophages.
TMA2576 Episappanol IL Receptor , TNF
Episappanol has anti-inflammatory activity , it can significantly inhibit the secretion of the pro-inflammatory cytokines interleukin (IL-6) and tumor necrosis factor-alpha (TNF-α).
TN2102 Procurcumenol Others , TNF
Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a).
T82578 Desacetylxanthanol
Desacetylxanthanol (Compound 4), a sesquiterpenoid originating from Xanthium strumarium, exhibits anti-tumor necrosis factor-associated apoptosis-inducing ligand (TRAIL) activity [1].
T21577 Narasin (sodium salt) Naracin sodium salt,naransin sodium,HainanMycin NF-κB
Narasin (sodium salt) (HainanMycin) induces tumor necrosis factor-related apoptosis-induced ligand (TRAIL)-mediated apoptosis by ER stress in glioma cells and inhibits NF-κB signaling by suppressing the phosphorylation o...
TN5238 Viscidulin II IL Receptor , TNF
Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of ...
TN5474 Bonducellin
Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bon...
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Natural Products

Geraniin
T6S2099
Synonym:
Target: Antioxidant, TNF
Hypaconitine
T6S0630
Synonym:
Target: P450, TNF
HOMOPLANTAGININ
T4S0217
Synonym:
Target: TNF, NF-κB
Mulberroside A
T6S1597
Synonym:
Target: TNF, Tyrosinase, Interleukin
Mesaconitine
T6S0627
Synonym:
Target: TNF
Fisetin
T2879
Synonym:
Target: TNF, Sirtuin, PPAR
Forsythoside B
T3893
Synonym:
Target: TNF, NF-κB
Sinensetin
T4S0227
Synonym: Pedalitin permethyl ether
Target: TNF, PGE Synthase
1,4-Dicaffeoylquinic acid
T4S1521
Synonym:
Target: HIV Protease
Ginsenoside Rc
T2720
Synonym: Panaxoside Rc
Target: Others, TNF, GABA Receptor, Interleukin
Tryptanthrin
T7786
Synonym:
Target: DNA gyrase
2'-FUCOSYLLACTOSE
TN6796
Synonym: 2'-Fucosyl-D-lactose
Target: Others
Negletein
T2S0843
Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether
Target: IL Receptor, TNF, NOS, Interleukin
Muscone
T2893
Synonym: 3-Methylcyclopentadecanone,Methylexaltone
Target: MMP, TNF, NF-κB, NOD-like Receptor (NLR), P-gp, Interleukin
Madecassic acid
T2758
Synonym: 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose
Target: Others, TNF, COX, NO Synthase, Interleukin
Astilbin
T2794
Synonym: Neoastilbin,Taxifolin 3-O-rhamnoside,Isoastilbin,Taxifolin 3-rhamnoside,Neoisoastilbin
Target: TNF, NF-κB, Nrf2
Neochlorogenic acid
T6S1538
Synonym: trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid
Target: TNF, NF-κB, COX, Antibacterial, Interleukin
7,3',4'-Tri-O-methylluteolin
TN1291
Synonym: 5-Hydroxy-3',4',7-trimethoxyflavone
Target: TNF, COX, Interleukin
Shikonin
T1125
Synonym: NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid
Target: TNF, NF-κB, Chloride channel, HIV Protease, PKM
Ginsenoside Rh1
T2932
Synonym: Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1
Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin
β-Anhydroicaritin
T6S2140
Synonym: Anhydroicaritin,Beta-Anhydroicaritin
Target: MMP, Others, TNF, Interleukin
Sodium taurocholate
TWA2417
Synonym: Taurocholate Sodium
Target: Others
4-hydroxyphenyl acetate
T8704
Synonym:
Target: Nrf2
Pseudotropine
PDK0060
Synonym:
Target: Others
Myristoleic acid
T41288
Synonym: cis-9-tetradecenoic acid,9-Tetradecenoic acid,(Z)-Tetradec-9-enoic acid
Target: Apoptosis
2'-Hydroxychalcone
TN1163
Synonym:
Target: Others
Protohypericin
TN2108
Synonym:
Target: Others
tubuloside B
T8852
Synonym:
Target: Apoptosis, Others
Taurocholic acid
TN2259
Synonym: N-Choloyltaurine
Target: TNF, PI3K
Usnic Acid
T2731
Synonym: Usniacin
Target: Antibacterial, Autophagy
Menthone
T5660
Synonym:
Target: IL Receptor, TNF, NF-κB, Parasite
Cepharanthine
T0131
Synonym: NSC-623442
Target: Apoptosis, TNF, HIV Protease, Autophagy
Hydroxysafflor yellow A
T3674
Synonym: HSYA,Safflomin A
Target: TGF-beta/Smad
Dihydrochelerythrine
T3S0057
Synonym: 12,13-Dihydrochelerythrine
Target: Antifungal
Docetaxel trihydrate
T0186
Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate
Target: Apoptosis, BCL, Microtubule Associated
(E/Z)-Squalene
T75636
Synonym: (E/Z)-Super Squalene,(E/Z)-AddaVax
Target:
4-Methoxycinnamyl alcohol
TN3049
Synonym:
Target: Others
Erianin
T3864
Synonym:
Target: BCL, Antibacterial
Ruscogenin
T6S1256
Synonym:
Target: NOS, NF-κB, NOD-like Receptor (NLR)
Monotropein
T6S1579
Synonym: Monotropeine
Target: Others
Crocin
T2823
Synonym: Gardenia Yellow,Alpha-Crocin
Target: Others
Linalool
T2S2264
Synonym: Linalol,(±)-Linalool,Phantol
Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR
5-Aminovaleric acid
T5089
Synonym:
Target: Others, Endogenous Metabolite
Lansiumarin C
TN4409
Synonym:
Target: TNF
Episappanol
TMA2576
Synonym:
Target: IL Receptor, TNF
Procurcumenol
TN2102
Synonym:
Target: Others, TNF
Desacetylxanthanol
T82578
Synonym:
Target:
Narasin (sodium salt)
T21577
Synonym: Naracin sodium salt,naransin sodium,HainanMycin
Target: NF-κB
Viscidulin II
TN5238
Synonym:
Target: IL Receptor, TNF
Bonducellin
TN5474
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02202 TNF alpha Protein, Rat, Recombinant Rat E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-03101 TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-05504 4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated Rhesus HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-03645 BAFF/TNFSF13B Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor family. BAFF is abundantly expressed in peripheral blood Leuko...
TMPY-01429 RELT/TNFRSF19L Protein, Human, Recombinant (His) Human HEK293
Receptor expressed in lymphoid tissues (RELT), also known as tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), is a member of the TNF-receptor superfamily. This receptor is especially abundant in he...
TMPY-03213 BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04289 CD30L Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s...
TMPJ-00779 TNF alpha Protein, Rabbit, Recombinant Rabbit E. coli
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty...
TMPY-00936 TNF alpha Protein, Human, Recombinant Human E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-04146 TNF alpha Protein, Human, Recombinant (hFc) Human HEK293
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-00705 CD30L Protein, Human, Recombinant (hFc) Human HEK293
CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell s...
TMPJ-00139 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) Human E. coli
Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain...
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His) Human HEK293
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-05568 BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04645 TL1A Protein, Human, Recombinant (hFc) Human HEK293
TL1A, also known as TNFSF15, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is specifically expressed in endothelial cells. TL1A also can be detected in monocytes, placenta, lung, liver, ...
TMPY-05376 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc) Human HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-00033 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) Human HEK293
4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as de...
TMPY-04493 BCMA/TNFRSF17 Protein, Human, Recombinant (rFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05594 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His) Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)...
TMPY-02726 RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPY-01294 TNF alpha Protein, Mouse, Recombinant Mouse E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-01743 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His) Human HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-01423 OX40/TNFRSF4 Protein, Human, Recombinant (His) Human HEK293
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea...
TMPJ-01466 Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His) Human Human Cells
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ...
TMPY-01750 HVEM Protein, Human, Recombinant (His) Human HEK293
Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-04832 OX40L/TNFSF4 Protein, Human, Recombinant (hFc) Human HEK293
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med...
TMPJ-00994 LTBR Protein, Mouse, Recombinant (hFc) Mouse Human Cells
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce...
TMPY-02096 TACI Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF...
TMPY-05767 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His) Mouse HEK293
CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-03674 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc) Human HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPY-04722 DcR1/TRAILR3 Protein, Human, Recombinant (His) Human HEK293
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most ...
TMPY-03364 RANKL/TNFSF11/CD254 Protein, Human, Recombinant Human HEK293
Tumor necrosis factor ligand superfamily member 11, also known as Receptor activator of nuclear factor kappa-B ligand, Osteoprotegerin ligand, TNFSF11, RANKL, TRANCE, OPGL and CD254, is a single-pass type II membrane pro...
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-05365 BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated Human HEK293
B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor family. BAFF is abundantly expressed in peripheral blood Leuko...
TMPY-01920 BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) Human HEK293
B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is a single-pass type II membrane protein, which belongs to the tumor necrosis factor family. BAFF is abundantly expressed in peripheral blood Leuko...
TMPY-01166 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-02069 TNF alpha Protein, Cynomolgus, Rhesus, Recombinant Cynomolgus,Rhesus E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPJ-00603 TL1A Protein, Mouse, Recombinant Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor ...
TMPY-05516 TNF alpha Protein, Cynomolgus, Recombinant, Biotinylated Cynomolgus E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-02226 TNF alpha Protein, Ferret, Recombinant Ferret E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPY-01594 TNF alpha Protein, Canine, Recombinant Canine E. coli
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological...
TMPJ-00280 TNF R1 Protein, Mouse, Recombinant Mouse E. coli
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate t...
TMPY-03680 BAFFR/TNFRSF13C Protein, Rat, Recombinant (His) Rat HEK293
Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosi...
TMPY-03909 BAFFR/TNFRSF13C Protein, Rat, Recombinant (hFc) Rat HEK293
Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosi...
TMPY-03588 TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (hFc) Cynomolgus,Rhesus HEK293
Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-05091 OX40/TNFRSF4 Protein, Rat, Recombinant (hFc) Rat HEK293
OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a rea...
TMPY-01185 DR5/TRAIL R2 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor super...
TMPY-03374 TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc) Human,Cynomolgus HEK293
TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue dis...
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TNF alpha Protein, Rat, Recombinant
TMPY-02202
Species: Rat
Expression System: E. coli
TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-03101
Species: Cynomolgus,Rhesus
Expression System: HEK293
4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated
TMPY-05504
Species: Rhesus
Expression System: HEK293
BAFF/TNFSF13B Protein, Cynomolgus, Recombinant (hFc)
TMPY-03645
Species: Cynomolgus
Expression System: HEK293
RELT/TNFRSF19L Protein, Human, Recombinant (His)
TMPY-01429
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)
TMPY-03213
Species: Rhesus
Expression System: HEK293
CD30L Protein, Cynomolgus, Recombinant (His)
TMPY-04289
Species: Cynomolgus
Expression System: HEK293
TNF alpha Protein, Rabbit, Recombinant
TMPJ-00779
Species: Rabbit
Expression System: E. coli
TNF alpha Protein, Human, Recombinant
TMPY-00936
Species: Human
Expression System: E. coli
TNF alpha Protein, Human, Recombinant (hFc)
TMPY-04146
Species: Human
Expression System: HEK293
CD30L Protein, Human, Recombinant (hFc)
TMPY-00705
Species: Human
Expression System: HEK293
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)
TMPJ-00139
Species: Human
Expression System: E. coli
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
TMPY-05319
Species: Human
Expression System: HEK293
CD30/TNFRSF8 Protein, Human, Recombinant (His)
TMPY-01827
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
TMPY-05568
Species: Human
Expression System: HEK293
TL1A Protein, Human, Recombinant (hFc)
TMPY-04645
Species: Human
Expression System: HEK293
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)
TMPY-05376
Species: Human
Expression System: HEK293
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)
TMPY-00033
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)
TMPY-04493
Species: Human
Expression System: HEK293
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-05594
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Human, Recombinant (His)
TMPY-00072
Species: Human
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (hFc)
TMPY-02726
Species: Mouse
Expression System: HEK293
TNF alpha Protein, Mouse, Recombinant
TMPY-01294
Species: Mouse
Expression System: E. coli
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)
TMPY-01743
Species: Human
Expression System: HEK293
OX40/TNFRSF4 Protein, Human, Recombinant (His)
TMPY-01423
Species: Human
Expression System: HEK293
Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
TMPJ-01466
Species: Human
Expression System: Human Cells
HVEM Protein, Human, Recombinant (His)
TMPY-01750
Species: Human
Expression System: HEK293
OX40L/TNFSF4 Protein, Human, Recombinant (hFc)
TMPY-04832
Species: Human
Expression System: HEK293
LTBR Protein, Mouse, Recombinant (hFc)
TMPJ-00994
Species: Mouse
Expression System: Human Cells
TACI Protein, Human, Recombinant (His)
TMPY-02096
Species: Human
Expression System: HEK293
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His)
TMPY-05767
Species: Mouse
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (mFc)
TMPY-03674
Species: Human
Expression System: HEK293
DcR1/TRAILR3 Protein, Human, Recombinant (His)
TMPY-04722
Species: Human
Expression System: HEK293
RANKL/TNFSF11/CD254 Protein, Human, Recombinant
TMPY-03364
Species: Human
Expression System: HEK293
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
TMPY-04142
Species: Human
Expression System: HEK293
BAFF/TNFSF13B Protein, Human, Recombinant (Avi & Fc), Biotinylated
TMPY-05365
Species: Human
Expression System: HEK293
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
TMPY-01920
Species: Human
Expression System: HEK293
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)
TMPY-01166
Species: Human
Expression System: HEK293
TNF alpha Protein, Cynomolgus, Rhesus, Recombinant
TMPY-02069
Species: Cynomolgus,Rhesus
Expression System: E. coli
TL1A Protein, Mouse, Recombinant
TMPJ-00603
Species: Mouse
Expression System: E. coli
TNF alpha Protein, Cynomolgus, Recombinant, Biotinylated
TMPY-05516
Species: Cynomolgus
Expression System: E. coli
TNF alpha Protein, Ferret, Recombinant
TMPY-02226
Species: Ferret
Expression System: E. coli
TNF alpha Protein, Canine, Recombinant
TMPY-01594
Species: Canine
Expression System: E. coli
TNF R1 Protein, Mouse, Recombinant
TMPJ-00280
Species: Mouse
Expression System: E. coli
BAFFR/TNFRSF13C Protein, Rat, Recombinant (His)
TMPY-03680
Species: Rat
Expression System: HEK293
BAFFR/TNFRSF13C Protein, Rat, Recombinant (hFc)
TMPY-03909
Species: Rat
Expression System: HEK293
TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (hFc)
TMPY-03588
Species: Cynomolgus,Rhesus
Expression System: HEK293
OX40/TNFRSF4 Protein, Rat, Recombinant (hFc)
TMPY-05091
Species: Rat
Expression System: HEK293
DR5/TRAIL R2 Protein, Human, Recombinant (His)
TMPY-01185
Species: Human
Expression System: HEK293
TWEAK/TNFSF12 Protein, Human, Cynomolgus, Recombinant (mFc)
TMPY-03374
Species: Human,Cynomolgus
Expression System: HEK293
Cat No. Product Name
L8720 Pyroptosis Compound Library

1077 compounds
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L8710 Cuproptosis Compound Library

411 compounds
TargetMol’s Cuproptosis Compound Library is a collection of 411 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.
L9000 Apoptosis Compound Library

1796 compounds
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
TargetMol