mold

Moldapyranone A is a natural product that can be used in related research in the field of life sciences. Its product number is TN8808.

Moldapyranone B is a natural product that can be used in related research in the field of life sciences. Its product number is TN8809.

Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.

Monascin, an azaphilonoid pigment extracted from Monascus pilosus-fermented rice (red-mold rice), exhibits anti-tumor-initiating and anti-inflammatory activities.

Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase α and δ, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].

Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor.

Fumigaclavine A, a clavine alkaloid mycotoxin produced by Aspergillus fumigatus, can be isolated from mold-contaminated silage [1].

Jervinone, an alkaloid metabolite derived from Veratrum, is isolated from the mold Cunninghamella echinulata [1].

Malolactomycin C (compound 1) is a macrocyclic lactone antifungal antibiotic isolated from the Streptomyces strain KP-3144. It effectively inhibits Botrytis cinerea (gray mold), thereby controlling various plant diseases, including gray mold infections.

Nocapyrone Q is a polyketide compound identified in the karst cave mold Streptomyces sp. FD-2-6. At a concentration of 100 μM, Nocapyrone Q shows inhibitory activity against human hepatocellular carcinoma HepG2 cells and human cervical cancer HeLa cells. Nocapyrone Q holds potential for research in the field of anticancer studies.