lipid 8

Lipid 8, an ionizable amino lipid, is employed in the synthesis of Lipid Nanoparticles (LNPs).

Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1 EDG-1, S1P2 EDG-5, S1P3 EDG-3, S1P4 EDG-6, and S1P5 EDG-8. W140 is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 μM (2a = W146; 2b = W140 in supplemental material). It exhibits no biological activity in vivo and can therefore serve as an effective control compound for experiments involving W146.

1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate is a PEG lipid used in drug delivery research [1].

Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate is employed in lipid nanoparticle (LNP) delivery systems for mRNA vaccine delivery [1].

LNP Lipid-4 (Compound 8-8) is a lipid compound integral to the synthesis of lipid nanoparticle compositions, demonstrating potential for the transport of biologically active substances [1].

Heptadecan-9-yl 8-bromooctanoate is a chemical compound that can be utilized in the construction or modification of lipid nanoparticles.

C8 Ceramide-1-phosphate (d18:1 8:0) is a lipid molecule that can be used in life science related research. The CAS number of C8 Ceramide-1-phosphate (d18:1 8:0) is 158983-53-0.

Heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate is a lipid utilized in compound synthesis.