leucovorin

Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.

Folinic acid (Leucovorin) is a biofolate used in the treatment of methotrexate (MTX) toxicity reduction and as an adjuvant therapy for colon cancer.

Folinic Acid Calcium Salt Pentahydrate (Leucovorin Calcium Pentahydrate), a reduced folic acid, is used in combination with other chemotherapeutics.

6R-Leucovorin is a derivative of Folic Acid.

Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.

Levoleucovorin, as a folate analog, consists of the pharmacologically active isomer of leucovorin.

Levoleucovorin disodium is the sodium salt of the enantiomerically active form of Folinic Acid.

Anhydroleucovorin is the predominant, biologically active form of vitamin B9 (folate) that is utilized by the body for a multitude of vital cellular functions, including DNA synthesis, repair, and methylation, as well as the production of key neurotransmitters; Anhydroleucovorin plays an essential metabolic role in the remethylation pathway, converting the amino acid homocysteine to methionine, and serves as the main folate form found in systemic circulation and transported into tissues for physiological use.

Anhydroleucovorin (Standard) is a reference standard for research and analysis in studies involving Anhydroleucovorin. Anhydroleucovorin is the predominant, biologically active form of vitamin B9 (folate) that is utilized by the body for a multitude of vital cellular functions, including DNA synthesis, repair, and methylation, as well as the production of key neurotransmitters; Anhydroleucovorin plays an essential metabolic role in the remethylation pathway, converting the amino acid homocysteine to methionine, and serves as the main folate form found in systemic circulation and transported into tissues for physiological use.

FOLFIRI Regimen is a chemotherapy regimen consisting of leucovorin calcium (calcium folinate), 5-fluorouracil, and irinotecan used during the treatment of advanced-stage and metastatic colorectal cancer.

Folinic acid (Leucovorin) calcium hydrate is a biofolic acid commonly used as a rescue agent with methotrexate (MTX) to mitigate MTX-induced toxicity.

Antileishmanial agent-21 (compound 4e) functions as an inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1), employing an anti-folate mechanism. Its antileishmanial effects can be negated by folic acid and leucovorin. Additionally, it demonstrates inhibitory activity against the chloroquine-resistant Plasmodium falciparum strain RKL9, with an IC50 ranging from 0.0198 to 0.096 μM [1].

Folinic acid-d4-1 (Leucovorin-d4-1) calcium hydrate is a deuterium-labeled version of Folinic acid. Folinic acid (Leucovorin) is a bioactive form of folate, frequently used alongside Methotrexate (MTX) as a rescue agent to mitigate the toxicity induced by MTX.