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By Target- Integrin
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Results for "
integrinβ-4
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Inhibitory Antibodies1
- Recombinant Protein7
- Antibody Products9
α4β7 Integrin-IN-1
T2141542417307-52-7
α4β7Integrin-IN-1 (Example 356) is a potent inhibitor of the α4β7 integrin, effectively blocking the interaction between α4β7 integrin and MadCAM-1 with an EC50 of 0.05 nM. This compound is utilized in research related to inflammatory bowel disease.
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α4 integrin receptor antagonist 3
T89582863226-74-8
Compound 11, an α4 integrin receptor antagonist, exhibits oral activity and functions as an antagonist of the α4 integrin receptor. It efficiently inhibits the adhesion of K562 cells mediated by the interactions of α4β1/VCAM-1 and α4β7/MAdCAM-1, with IC50 values of 130 nM and 2 nM, respectively. Compound 11 also shows potential for use in studies using the DSS (dextran sulfate sodium) induced colitis mouse model.
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Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32)
T9901A-503
Anti-Mouse LPAM-1/Integrinα4β7 Antibody (DATK32) is a rat-derived IgG2a, κ antibody inhibitor targeting mouse LPAM-1/Integrinα4β7.
- $260
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