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ink4a/arf

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  • Inhibitors & Agonists
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MS37452
T21767423748-02-1
MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).
  • $47
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Methylbenzoprim
NSC-382035, TYMS inhibitor 19-S, NSC 382035, NSC382035, TYMS In 19-S, TYMS In 19S, TYMS-In-19-S, TYMS-In-19S
T202109118344-71-1
Methylbenzoprim is an innovative multifunctional thymidylate synthase (TYMS) inhibitor. It exhibits greater antitumor activity compared to current fluoropyrimidines and antifolates, without inducing TYMS overexpression. In pancreatic xenograft tumor models and hTS Ink4a Arf null genetically engineered mouse models, Methylbenzoprim effectively prolongs survival.
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10-14 weeks
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