hepatocyte injury

Homoplantaginin, a flavonoid derived from the traditional Chinese medicine Salvia plebeia, exhibits protective and therapeutic effects on hepatocyte injury and demonstrates potent inhibitory activities against influenza.

Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheimer desease treatment.

Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity.

Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the research of hepatocellular injury.

Isotaxiresinol prevents d-GalN LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha. Isotaxiresinol ma

Kaerophyllin ( (-)-Kaerophylin), a lignan isolated from the traditional Chinese medicine Chai Hu, inhibits activation of hepatic stellate cells by hepatocyte apoptotic vesicles, and protects rat liver from TAA-induced injury and fibrosis by suppressing hepatic inflammation and inhibiting HSC activation.

Limonexic acid shows antinociceptive actions , it produces dose-related inhibition of glutamate- and capsaicin-induced pain. Limonexic acid can effectively protect hepatocyte against CCl4-induced injury.